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Antifungal activity from aerial part extracts of Leptadeniapyrotechnica (Forsskal.) Decne from the Cholistan Desert, Pakistan

Research Paper | August 1, 2015

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Shaista Jamil, Saeed Ahmad, Hafiz Muhammad Wariss, Jiang Wei, Tahir Mehmood, Muhammad Afzal, Zafar Iqbal

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Int. J. Biosci.7( 2), 29-35, August 2015

DOI: http://dx.doi.org/10.12692/ijb/7.2.29-35


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This study was carried out with an objective to investigate the antifungal potentials of aerial part of leptadeniapyrotechnica (Forssk) Decne. The aim of the study is to assess the antifungal activity and to determine the zone of inhibition of extracts on fungal strains. The experiment based on ethno-medicinal survey, in the present study, the antifungal activity of methanol, hexane, ethyl acetate and water extracts of aerial part of leptadeniapyrotechnicawas evaluated for potential antifungal activity against pathogenic fungal strains. The antifungal activity was determined in the extracts using disc diffusion method. The antifungal activities of extracts (1.8, 2.9, 6.5, 12.6, 25, 50, and 75μg/ml) of leptadeniapyrotechnicawere tested against five fungal strains Aspergillusflavus, A.fumigatus, A. niger, A. ustusand Candida albicans. Zone of inhibition of extracts were compared with that of standards drug, Flucanazole antifungal activity. The results showed that the remarkable zone of inhibition of the fungal growth was shown against the tested fungi. The antifungal activity of the leptadeniapyrotechnicawas due to the presence of various secondary metabolites. Hence, these plants can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.


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Antifungal activity from aerial part extracts of Leptadeniapyrotechnica (Forsskal.) Decne from the Cholistan Desert, Pakistan

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