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Antimicrobial activities and GC-MS chemical profiling of methanol extracts of different parts of Morus alba (Tut) in Bangladesh

Md. Sabbir Hasan, Mahci Al Bashera, Shyama Prosad Moulick, Fatema Tuz Jubyda, Md. Jahidul Islam, Mst. Sarmina Yeasmin, Md. Badrul Islam

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Int. J. Biosci.18(5), 156-166, May 2021

DOI: http://dx.doi.org/10.12692/ijb/18.5.156-166


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Morus alba has potential therapeutic value in different medicinal parts. We investigated the chemical differences presence in the methanolic extract (ME) of leaves, stem and root M. alba using GC-MS technique. GC-MS based phyto-chemical profiling revealed the presence of potent bioactive components in methanolic extracts of different parts (leaves, stem and root) of M. alba. Further, GC-MS study confirmed the occurrence of twenty to thirty bioactive constituents ranging from 0.06 to 32% based on their peak area. Among different methanolic extract of M. alba maximum number of phytocompounds were observed in leaves extract with glycerin (32.77%) as predominant compound and lowest in root bark (SBP) extract which is dominated hexadecanoic acid methyl ester (30.55%) respectively. Furthermore, all the study extracts were also screened for their antimicrobial activity and only stem bark extract (SBP) were found to active against both gram positive and gram negative bacteria but all are inactive against fungal strain.


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Antimicrobial activities and GC-MS chemical profiling of methanol extracts of different parts of Morus alba (Tut) in Bangladesh

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