Antimicrobial activities and GC-MS chemical profiling of methanol extracts of different parts of Morus alba (Tut) in Bangladesh
Paper Details
Antimicrobial activities and GC-MS chemical profiling of methanol extracts of different parts of Morus alba (Tut) in Bangladesh
Abstract
Morus alba has potential therapeutic value in different medicinal parts. We investigated the chemical differences presence in the methanolic extract (ME) of leaves, stem and root M. alba using GC-MS technique. GC-MS based phyto-chemical profiling revealed the presence of potent bioactive components in methanolic extracts of different parts (leaves, stem and root) of M. alba. Further, GC-MS study confirmed the occurrence of twenty to thirty bioactive constituents ranging from 0.06 to 32% based on their peak area. Among different methanolic extract of M. alba maximum number of phytocompounds were observed in leaves extract with glycerin (32.77%) as predominant compound and lowest in root bark (SBP) extract which is dominated hexadecanoic acid methyl ester (30.55%) respectively. Furthermore, all the study extracts were also screened for their antimicrobial activity and only stem bark extract (SBP) were found to active against both gram positive and gram negative bacteria but all are inactive against fungal strain.
Abdullah, Al-shwyeh Hussah, Mohamed Elwathig, Saeed Mirghani, Parveen Jamal. 2011. “Antibacterial Activity of Malaysian Mango Kernel” 10(81), 18739–48. https://doi.org/10.5897/AJB11.2746.
Avci, Emre. 2016. “Antioxidant and Antimicrobial Activities with GC/MS Analysis of the Morus alba L. Leaves,” no. March. http://dx.doi.org/10.17350/HJSE19030000006
Bayer AW, Kirby WMM, Sherris JC, Turck M. 1966. “Antibiotic Susceptibility Testing by a Standardized Single Disc Method.” Americal Journal of Clinical Pathology 45(4), 493–96.
Choi Youngmin, Junsoo Lee. 2009. “Antioxidant and Antiproliferative Properties of a Tocotrienol-Rich Fraction from Grape Seeds.” Food Chemistry 114(4), 1386—1390. https://doi.org/10.1016/j.foodchem.2008.11.018.
Datta RK. 2000. “Mulberry Cultivation and Utilization in India.” FAO Animal Production and Health Paper, 45–62.
Devi, Bandna, Neha Sharma, Dinesh Kumar, Kamal Jeet. 2013. “Morus Alba Linn: A Phytopharmacological Review.” International Journal of Pharmacy and Pharmaceutical Sciences 5(2), 14–18.
Hajji, Mohamed, Raoudha Jarraya, Imen Lassoued, Ons Masmoudi, Mohamed Damak, Moncef Nasri. 2010. “GC/MS and LC/MS Analysis, and Antioxidant and Antimicrobial Activities of Various Solvent Extracts from Mirabilis Jalapa Tubers.” Process Biochemistry 45(9), 1486–93. https://doi.org/10.1016/j.procbio.2010.05.027.
Joshi, Shivani, Devendra Mishra, Ganga Bisht, Khadak Singh Khetwal. 2011. “Essential Oil Composition and Antimicrobial Activity of Lobelia Pyramidalis Wall.” EXCLI Journal 10, 274–79.
Kim, Jung-Hoon, Eui-Jeong Doh, Guemsan Lee. 2020. “Quantitative Comparison of the Marker Compounds in Different Medicinal Parts of Morus Alba L. Using High-Performance Liquid Chromatography-Diode Array Detector with Chemometric Analysis.” Molecules 25(23), 5592.
Kumaradevan G, Damodaran R, Mani P, Dineshkumar G, Jayaseelan T. 2015. “Phytochemical Screening and GC-MS Analysis of Bioactive Components of Ethanol Leaves Extract Of Clerodendrum Phlomidis (L.)”. American Journal of Biological and Pharmaceutical Research 2, 142–48.
Mahboubi, Mohaddese. 2019. “Morus Alba (Mulberry), a Natural Potent Compound in Management of Obesity.” Pharmacological Research 146, 104341. https://doi.org/10.1016/j.phrs.2019.104341.
Perelman, Patricia, Ana Faggi, Maria Castro, Eduardo Martinez Carretero. 2010. “Pollution Trends Using Bark of Morus Alba in the Cities of Buenos Aires and Mendoza (Argentina).” Revista Árvore 34(3), 505–11. https://doi.org/10.1590/s010067622010000300014.
Pinto Maria EA, Sthéfane Araújo G, Marcela Morais I, Nívea Sá P, Caroline Lima M, Carlos Rosa A, Ezequias Siqueira P, Susana Johann, Luciana Lima ARS. 2017. “Antifungal and Antioxidant Activity of Fatty Acid Methyl Esters from Vegetable Oils.” Anais Da Academia Brasileira de Ciencias 89(3), 1671–81. https://doi.org/10.1590/0001-3765201720160908.
Rahman MM, Ahmad SH, Mohamed MTM, Ab Rahman MZ. 2014. “Antimicrobial Compounds from Leaf Extracts of Jatropha Curcas, Psidium Guajava, and Andrographis Paniculata.” Edited by Prasat Kittakoop. The Scientific World Journal 635240. https://doi.org/10.1155/2014/635240.
Rahman Md. Munsur. 2014. “Investigation Some Physicochemical Properties, Lipids, Glycerides and Fatty Acid Composition of Mulberry (Morus Alba L) Seed Oil of Three Different Regions of Bangladesh.” American Journal of Applied Chemistry 2(3), 38. https://doi.org/10.11648/j.ajac.20140203.11.
Salem, Mohamed Zidan Mohamed, Hussein Aly, Yousry Gohar, Abdel-Wahab El-Sayed. 2013. “Biological Activity of Extracts from Morus Alba L., Albizzia Lebbeck (L.) Benth. and Casuarina Glauca Sieber Against the Growth of Some Pathogenic Bacteria.” International Journal of Agricultural and Food Research 2(1), 9–22. https://doi.org/10.24102/ijafr.v2i1.122.
Saravanan P, Chandramohan G, Mariajancyrani J, Shanmugasundaram P. 2014. “GC-MS Analysis of Phytochemical Constituents in Ethanolic Bark Extract of Ficus Religiosa Linn.” International Journal of Pharmacy and Pharmaceutical Sciences 6 (January), 457–60.
Vijayan, Kunjupillai, A Tikader, Zhao Weiguo, Chirakkara Nair, Chi-Hua Tsou. 2011. “Morus,” June. https://doi.org/10.1007/978-3-642-20447-0_5.
Wang, Wei, Yuangang Zu, Yujie FU, Thomas Efferth. 2012. “In Vitro Antioxidant and Antimicrobial Activity of Extracts from Morus Alba L. Leaves, Stems and Fruits.” American Journal of Chinese Medicine 40(2), 349–56. https://doi.org/10.1142/S0192415X12500279.
Zhou BL, Chen ZX, Du L, Xie YH, Zhang Q, Ye XL. 2011. “Allelopathy of Root Exudates from Different Resistant Eggplants to Verticillium Dahliae and the Identification of Allelochemicals” 10(42), 8284–90. https://doi.org/10.5897/AJB10.2300.
Md. Sabbir Hasan, Mahci Al Bashera, Shyama Prosad Moulick, Fatema Tuz Jubyda, Md. Jahidul Islam, Mst. Sarmina Yeasmin, Md. Badrul Islam (2021), Antimicrobial activities and GC-MS chemical profiling of methanol extracts of different parts of Morus alba (Tut) in Bangladesh; IJB, V18, N5, May, P156-166
https://innspub.net/antimicrobial-activities-and-gc-ms-chemical-profiling-of-methanol-extracts-of-different-parts-of-morus-alba-tut-in-bangladesh/
Copyright © 2021
By Authors and International
Network for Natural Sciences
(INNSPUB) https://innspub.net
This article is published under the terms of the
Creative Commons Attribution License 4.0