Antimicrobial activity and phytochemical screening of Maerua pseudopetalosa (Glig and Bened.) DeWolf

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Research Paper 01/08/2015
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Antimicrobial activity and phytochemical screening of Maerua pseudopetalosa (Glig and Bened.) DeWolf

Manal A. Ibrahim, El Bushra E. El Nur, Mohammad H. Awad
Int. J. Biosci.7( 2), 170-177, August 2015.
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Abstract

Chloroform, ethyl acetate and ethanol, which were used for the extraction of Maerua. pseudopetalosa parts, gave nine extracts with different colors, consistencies and extractabilities. Four bacterial strains (Bacillus cereus, Escherichia coli, Staphylococcus aureus and Salmonella typhi, and three fungal species: Aspergillus fumigatus, Aspergillus flavus and Candida albicans) were tested for antimicrobial activities of the extracts. The antibacterial activity was of the limited type (only 11%); while antifungal activity showed considerable variations depending on the type of the extract, the fungus and the duration of the treatment. Tests for secondary metabolites proved the presence of tannins, sterolsL and alkaloids. The detection of sterols, alkaloids, flavonoids and cardiac glycosides were proved by TLC separation in the crude extracts.

VIEWS 4

Al Magboul AZ, Bashir A, Salih AM, Farouk A, Khalid SA. 1987. Antimicrobial activity of certain Sudanese plants used in folkloric medicine: Screening for antibacterial activity(v). Fitoterapia 59, 57-62.

Ali Y, Riza N, kalhoro AM, Abdulmalik M. 2008. Phytochemical studies on Maerua arenaria. Journal of Chemical Society Pakistan 30(1), 112-118.

Amaechi NC. 2009. Nutritive and anti-nutritive evaluation of wonderful kola (Buccholzia coricea) Seeds. Pakistan Journal of Nutrition 8(8), 1120-112 2.

Fiedler HP. 2004. Screening for bioactivity. In: Microbial diversity and bioprospecting, A.T. Bull ed. ASM, Press, Washington. 324-335 P.

Harborne JB. 1973.  Phytochemical  Methods:  A guide to modern techniques of plants analysis. Champnan and Hall Press. London. University of Reading. 30-33 P.

Harborne JB. 1998. Phytochemical Methods:  A guide to modern techniques of plant analysis. Champman and Hall press. London. University of Reading. 43-46 P.

Henry AJ. 1948. The toxic principle of Courbonia virgata: Its isolation and identification as a tetramethylammonium salt. Birt. Journal of Pharmacology 3, 187. http://dx.doi.org/10.1089/jmf.2007.625

Kavanagh F. 1972. Analytical Microbiology. Academic Press. New York and London.II. 11 P.

Mohammed EE. 2007. Phytochemical and biological investigations on essential oils of six Sudanese medicinal plants. M.Sc. thesis, Unversity Of Khartoum, Sudan. 22-24

Nandani D, Verma RN, Batra A. 2013. Isolation and identification of quercetin and emodin from Cassia tora L. Annals of Phytomedicine 2, 96-104.

Ojiako OA, Igwe CV. 2007. Nutritional and anti-nutritional compositions of Cleome rutidosperma, Lagenariasiceraria and Cuscurbita maxima seeds from Nigeria. Journal of Medicinal Food 10(4), 735 – 738.

Upasani SM, Kothar HM, Mendki PS, Maheshwari VL. 2003. Partial characterization and insecticidal properties of Ricinus communis L. follage flavonoids. Pest Management Sciences 59, 1349-1354.

Wagner H, Bladt S, Zgainski EM. 1996. Plant Drug Analysis. Athin layer chromatography atlas. Spring – Verlag. Berlin New York Tokyo. 102 P.