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Antimicrobial analysis of root and shoot extracts of Ephedra intermedia Schrenk & Meyer

Muhammad Sabir Bangulzai, Saadullah Khan Leghari, Imran Ali, Mudassir Asrar, Tariq Ismail, Ayesha Mushtaq

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Int. J. Biosci.11(3), 86-94, September 2017

DOI: http://dx.doi.org/10.12692/ijb/11.3.86-94


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This study was done to estimate the antimicrobial activity of root and shoot extracts of Ephedra intermedia Schrenk & Meyer. The root and shoot extracts of Ephedra intermedia was tested against four Bacterial strains (Staphylococcus aureus, Escherichia coli, Pseudomonas fluorescens and Bacillus subtilis) and three fungal species (Fusarium verticilliodes, Aspergillus lavus and Dreschlera turcicia). In this study the Ephedra intermedia (root and shoot) methanol extract showed highest antibacterial actions against Staphylococcus aureus, followed by Escherichia coli and lowest activity was noted against Bacillus subtilis. The alcoholic and distilled water extracts of E. intermedia root and shoot also showed significant activity against all examined fungal species. The extreme antifungal activity through methanol extraction shown against Fusarium verticilliodes, which followed by Aspergillus flavus and lowest movement was reported against Dreschlera turcicia with minimum inhibition zone. Further that the methanol extract exhibited significant effect against all the investigated bacterial and fungal species as compared to the ethanol and distilled water extract. This study also showed that the roots of E. intermedia were more effective as compared to the shoots against under study bacterial and fungal species.


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Antimicrobial analysis of root and shoot extracts of Ephedra intermedia Schrenk & Meyer

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