Antimicrobial potential of the crude extracts of an ethno botanically important plant Quisqualis indica Linn.

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Research Paper 01/01/2017
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Antimicrobial potential of the crude extracts of an ethno botanically important plant Quisqualis indica Linn.

Ariba Shah, Zaheer-Ud-Din Khan, Shanzay Saleem
Int. J. Biosci.10( 1), 335-344, January 2017.
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Abstract

The organic and inorganic crude extracts of different plant parts of Quisqualis indica Linn; were obtained by maceration technique in n-hexane, chloroform, ethanol and water. The phytochemical screening of the crude extracts disclosed the presence of a variety of secondary metabolites, such as alkaloids, tannins, saponins, terpenoids, flavonoids, cardiac glucosides and reducing sugars. The crude extracts were also tested for their antibacterial and antifungal activities by using agar well diffusion method against gram-positive bacteria, i.e. Escherichia coli & Pseudomonas aeruginosa, gram-negative bacteria, i.e. Bacillus subtilis & Staphylococcus aureus and fungal strains Aspergillus niger & Aspergillus oryzae. The broad spectrum of potential in the form of zone of inhibition was exhibited against bacterial and fungal strains ranging from 9±0.3mm to 53±0.1mm and ±0.3mm to 51±0.4mm respectively. The maximum zone of inhibition, i.e. 53±0.1mm was developed by the ethanol root extract against B. subtilis, while the second and third largest zones of inhibition, i.e. 51±0.4 and 46±0.5 were shown by chloroform and ethanol root extracts respectively against fungal strains.

VIEWS 26

Ravikumar A, Subbu Rathinam KM. 2009. Antibacterial activity of hexane and acetone extracts of Peltophorum pterocarpum, Calvillea racemosa and Bauhinia purpurea. J. Chem. Sci 7(3), 1751-1756.

Heinrich M, Barnes J, Gibbons S, Williamson EM. 2004. In: Fundamentals of Pharmacognosy and Phytotherapy. Churchill Livingstone, Edinbrugh 245-252.

Graham JG, Quinn ML, Fabricant DS, Farnsworth NR. 2000. Plants used against cancer. Journal of Ethnopharmacology 73, 347-377.

Adebanjo AO, Adewumi CO, Essein EE. 1983. Anti-infective agents of higher plants. In: International Symposium of Medicinal Plants, fifth Ed. University of Ife, Nigeria 152-158.

Sokmen A, Jones BM, Erturk M. 1999. The in vitro antibacterial activity of Turkish medicinal plants. Journal of Ethnopharmacology 67, 79-86.

Martin-Bettolo GB. 1980. Present aspects of the use of medicinal plants in traditional medicine. Journal of Ethnopharmacology 2, 5-7.

Cowan MM. 1999. Plant products as antimicrobial agents. Clinical Microbiology Review 12, 564-582.

Graybill JR. 1988. Systemic fungal infections: diagnosis and treatment. I. Therapeutic agents. Infect. Dis. Clin. North. Am. 7, 805-825.

Ng PC. 1994. Systemic fungal infections in neonates. Arch. Dis. of Childhood 71, 130-135.

Dean DA, Burchard KW. 1996. Fungal infection in surgical patients. Am. J. Surg 171, 374-382.

Gonzalez CE, Venzon D, Lee S, Mueller BU, Pizzo PA, Walsh TJ. 1996. Risk factors for fungemia in children infected with human immunodeficiency virus: a case-control study. Clin. Infect. Dis 23, 515-521.

Sieradzki K, Wu SW, Tomasz A. 1999. Inactivation of the methicillin resistance gene mecA in vancomycin-resistant Staphylococcus aureus. Micro. Drug Resist. 5(4), 253-257.

Eloff JN. 1999. The antibacterial activity of 27 Southern African members of the Combretaceae. South African Journal of Science 95, 148-152.

Hanif A, Ahmad H, Begum S, Hussian SK, Adnan SM. 2004. Medicinal and other economic plants as substitute to forest logging in Miandam and Sulatanr Valley-Swat. Proc. of international workshop on conservation and sustainable use of Medicinal and aromatic plants in Pakistan. WWF- Pakistan.

Qaiser S, Quaiser M. 1978. Family Combretaceae. No. 122. In: Flora of West Pakistan. Eds. E. Nasir & S. I. Ali, Department of Botany, University of Karachi, Karachi.

Ayoola GA, Coker HA, Adesegun SA, Adepoju-Bello AA, Obaweya K, Ezennia EC, Atangbayila TO. 2008. Phytochemical Screening and Antioxidant Activities of Some Selected Medicinal Plants Used for Malaria Therapy in Southwestern Nigeria. Tropical Journal of Pharmaceutical Research 7(3), 1019-1024.

Oretega MG, Julian HR. 1996. Antimicrobial Agents in Dalea elegant. Fitoterapia 37, 81.

Ferreira, MJU, Daurte A, Ascenso JR. 1996. Antimicrobial and Phytochemical Studies of Euphorbia tuckeyana. Fitoterapia 37, 85-86.

Murray PR, Baron EJ, Pfaller MA, Tenevor FC, Yolke RH. 1999. Mannual of clinical Microbiology 1527-1539.

Hammer KA, Carson CF, Riley TV. 1999. Antimicrobial activity of essential oils and other plant extracts. Journal of Applied Microbiology 86(6), 985-990.

Tiwari BK, Valdramidis VP, O’Donnell CP, Muthukumarappan K, Bourke P, Cullen PJ. 2009. Application of natural antimicrobials for food preservation. Journal of Agricultural and Food Chemistry 57(14), 5987-6000.

Geissman TA. 1963. Flavonoid compounds, tannins, lignins and related compounds. Pyrrole pigments, isoprenoid compounds and phenolic plant constituents 265.

Schultes RE. 1978. The kingdom of plants. Medicines from the Earth 208.

Dixon RA, Dey PM, Lamb CJ. 1983. Phytoalexins: enzymology and molecular biology. Adv Enzymol 55, 1-69.

Tsuchiya H, Sato M, Miyazaki T, Fujiwara S, Tanigaki S, Ohyama M, Tanaka T, Iinuma M. 1996. Comparative study on the antibacterial activity of phytochemical flavanones against methicillin-resistant Staphylococcus aureus. J Ethnopharmacol 50, 27-34.

Toda M, Okubo S, Ohnishi R, Shimamura T. 1989. Antibacterial and bactericidal activities of Japanese green tea. Jpn J Bacteriol 45, 561-566.

Serafini M, Ghiselli A, Ferro-Luzzi A. 1994. Red wine, tea and anti-oxidants. Lancet 44, 626.

Haslam E. 1996. Natural polyphenols (vegetable tannins) as drugs: possible modes of action. J Nat Prod. 59, 205-215.

Schultz JC. 1988. Tannin-insect interactions. In: Chemistry and significance of condensed tannins 553.

Butler LG. 1988. Effects of condensed tannin on animal nutrition. In: Chemistry and significance of condensed tannins 553.

Chaurasia SC, Vyas KK. 1977. In vitro effect of some volatile oil against Phytophthora parasitica var.  piperina. J Res Indian Med Yoga Homeopath 24-26.

Wan J, Wilcock A, Coventry MJ. 1998. The effect of essential oils of basil on the growth of Aeromonas hydrophila and Pseudomonas fluorescens. J Appl Microbiol. 84, 152-158.

Fessenden RJ, Fessenden JS. 1982. In: Organic chemistry. 2nd ed. Boston, Mass: Willard Grant Press.

McMahon JB, Currens MJ, Gulakowski RJ, Buckheit RWJ, Lackman-Smith C, Hallock YF, Boyd MR. 1995. Michellamine B, a novel plant alkaloid, inhibits human immunodeficiency virus-induced cell killing by at least two distinct mechanisms. Antimicrob Agents Chemother 39, 484-488.

Sethi ML. 1979. Inhibition of reverse transcriptase activity by benzophenanthridine alkaloids. J. Nat Prod 42, 187-196.

McDevitt JT, Schneider DM, Katiyar SK, Edlind TD. 1996. Program and Abstracts of the 36th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C.: American Society for Microbiology. Berberine: a candidate for the treatment of diarrhea in AIDS patients 175.

Ghoshal S, Krishna Prasad BN, Lakshmi V. 1996. Antiamoebic activity of Piper longum fruits against Entamoeba histolytica in vitro and in vivo. J. Ethnopharmacol. 50, 167-170.

Singh B, Rastogi RP. 1970. Cardenolides-glycosides and genins. Phytochemistry 9, 315-331.

Das TK, Banerjee D, Chakraborty D, Pakhira MC, Shrivastava B, Kuhad RC. 2012. Saponin: Role in Animal system. Vet. World 5(4), 248-254.