Assessment of asthma causes identified by spirometry in Lahore, Pakistan

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Research Paper 01/12/2020
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Assessment of asthma causes identified by spirometry in Lahore, Pakistan

Syed Shahid Imran Bukhari, Zulfiqar Ali
Int. J. Biosci.17( 6), 202-217, December 2020.
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This study was done to find out the causes of asthma in population of Lahore, Pakistan. Total of 2003 subjects from 9 administrative towns of Lahore, Pakistan were divided into 3 groups; G1 (normal), G2 (asthmatics with obstruction) and G3 (asthmatics with restriction) for spirometry over 1-year period (July, 2018-2019) at Jinnah hospital, Lahore using (Spirolab, IPX1FCC ID: TUK-MIR045 Roma-Italy). From 2003 subjects, 400 were randomly selected for questionnaire study consisting normal (n=200) and asthmatics (n=200). There were 60% records from male patients and 40% from female patients between the age limit of 07-104 years. Questionnaire depicted that more than 90% asthmatic subjects feel wheezy; 50% people did not have heredity asthma but had attached kitchen and bath; 60% people had complicated life style and joint family system; have pets, cockroaches, carpets and molds; more than 60% subjects use gas stove in their indoor. Data was analyzed using x2 tests for questionnaire and Pearson’s correlation coefficient (r) using SPSS (v.22). FVC and FEV1 < 80% of value and FEV1/FVC ratio < 70% were considered asthmatic. There was positive correlation between age (p<0.05) and FVC among G1 and G2. Age and prevalence of asthma were significantly positively correlated (p<0.05) in G3. G2 & G3 showed forces expiratory volume in 1 second (FEV1) or peak expiratory flow (PEF) < 60%. FVC was significantly correlated positively (p<0.05) with asthma prevalence. There was significantly positive correlation (p<0.05) for asthma prevalence. Various factors under this study impair life quality of asthmatics.


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