Welcome to International Network for Natural Sciences | INNSpub

Paper Details

Research Paper | June 1, 2016

VIEWS 1
| Download 1

Biodegradation of ciprofloxacin in a continuous anaerobic hybrid reactor conglomerating attached and suspended growth system

Debleena Bhattacharya, S.K. Gupta

Key Words:


J. Bio. Env. Sci.8(6), 74-86, June 2016

Certification:

JBES 2016 [Generate Certificate]

Abstract

The detection of antibiotics in the natural surroundings needs immediate attention to control antibiotic pollution in the precious water resources and avoid generation of antibiotic resistant strains. The present study investigated the biodegradation of ciprofloxacin (CIP) containing wastewater in a continuous lab-scale anaerobic hybrid reactor (AHR), which conglomerates the dual advantages of attached and suspended growth. The reactor was started with the inoculum sludge, historically been exposed to the pharmaceutical residuals and fed with simulated synthetic wastewater for its acclimation to higher COD concentrations (1000 mg/L). CIP was then gradually infused in the bioreactor from 0.5 to 10 mg/L for acclimation of microorganisms till it attained CIP removal >90%. The acclimation study revealed that AHR could sustain CIP concentration as high as 5 mg/L beyond which the process severely got deteriorated. Zone of inhibition study was carried out to assess the tolerance level of bacterial strains to varying CIP concentrations. MS-QToF analysis of effluent samples identified 8 new organic intermediates. The anaerobic hybrid reactor proved to be a significant mode to control the pollution caused by the above group of antibiotics.

VIEWS 1

Copyright © 2016
By Authors and International Network for
Natural Sciences (INNSPUB)
http://innspub.net
This article is published under the terms of the Creative
Commons Attribution Liscense 4.0

Biodegradation of ciprofloxacin in a continuous anaerobic hybrid reactor conglomerating attached and suspended growth system

Amorim CL, Maia AS, Mesquita RBR, Rangel AOSS, Loosdrecht van MCM, Tiritan ME. 2014. Performance of aerobic granular sludge in a sequencing batch bioreactor exposed to ofloxacin, norfloxacin and ciprofloxacin. Water Research 50, 101–113.

Arya V, Philip L, Bhallamundi MS. 2016. Performance of suspended and attached growth bioreactors for the removal of cationic and anionic pharmaceuticals. Chemical Engineering Journal 284, 1295–1307.

Ashton D, Hilton M, Thomas KV. 2004. Investigating the environmental transport of human pharmaceuticals to streams in the United Kingdom. Science of The Total Environment 333, 167–184.

Batt AL, Kim S, Aga DS. 2007. Comparison of the occurrence of antibiotics in four full-scale wastewater treatment plants with varying designs and operations. Chemosphere 68, 428-435.

Chen Z, Ren N, Wang A, Zhang ZP, Shi Y. 2008. A. novel application of TPAD–MBR system to the pilot treatment of chemical synthesis-based pharmaceutical wastewater. Water Research 42, 3385–3392.

Chen YF, Ng WJ, Yap MGS. 1994. Performance of upflow anaerobic biofilter process in pharmaceutical wastewater treatment. Resources Conservation and Recycling 11, 83-91.

Calza P, Medana C, Carbone F, Giancotti V, Baiocchi C. 2008. Characterization of intermediate compounds formed upon photoinduced degradation of quinolones by high-performance liquid chromatography/high-resolution multiple-stage mass spectrometry. Rapid Communications in Mass Spectrometry 22, 1533-1552.

Chelliapan S, Wilby T, Sallis PT. 2006. Performance of an up-flow anaerobic stage reactor (UASR) treating pharmaceutical wastewater containing macrolide antibiotics. Water Research 40, 507–516.

Diwan V, Tamhankar AJ, Aggarwal M, Sen S. 2009.Detection of antibiotics in hospital effluents in India. Current Science 97, 12–15.

Duan X, Zhou J, Qiao S, Yin X, Tian T, Xu F. 2012. Start-up of the anammox process from the conventional activated sludge in a hybrid bioreactor. Journal of Environmental Sciences 24, 1083-1090.

Du J, Hu Y, Qi W, Zhang Y, Jing Z, Norton M, Li Y. 2015. Influence of four antimicrobials on methane-producing archaea and sulfate-reducing bacteria in anaerobic granular sludge. Chemosphere 140, 184–190.

Enick OV, Moore MM. 2007. Assessing the assessments: pharmaceuticals in the environment. Environmental Impact Assessment Review 27, 707– 729.

Enright AM, McHugh S, Collins G, Flaherty VO. 2005. Low-temperature anaerobic biological treatment of solvent containing pharmaceutical wastewater. Water Research 39, 4587–4596.

Falas P, Baillon-Dhumez A, Andersen HR, Ledin A, Jansen JLC. 2012. Suspended biofilm carrier and activated sludge removal of acidic pharmaceuticals. Water Research 46, 1167–1175.

Fent K, Weston AA, Caminada D. 2006. Ecotoxicology of human pharmaceuticals. Aquatic Toxicology 76,122-159.

Gad-Allah AT, Ali EM, Badawy IM. 2011. Photocatalytic oxidation of ciprofloxacin under simulated sunlight. Journal of Hazardous Materials 186, 751–755.

Garcia DN, Gómez ZA, Navalón A, González J, Vílchez JL. 2013. Removal of quinolone antibiotics from wastewaters by sorption and biological degradation in laboratory-scale membrane bioreactors. Science of The Total Environment 442, 317–328.

Grenni P, Patrolecco L, Ademollo N, Tolomei A, Caracciolo BA.2013. Degradation of Gemfibrozil and Naproxen in a river water ecosystem. Microchemical Journal 107, 158–164.

Gupta SK, Gupta SK. 2005. Morphological studies of granules in UASB and hybrid reactors. Clean Technologies and Environmental Policy 7, 203–212.

Gupta SK, Gupta SK, Singh G. 2007. Biodegradation of distillery spent wash in anaerobic hybrid reactor. Water Research 41, 721–730.

Ince O, Ince BK, Yenigun O. 2001. Determination of potential methane production capacity of a granular sludge from a pilot scale upflow anaerobic sludge blanket reactor using a specific methanogenic activity test. Journal of Chemical Technology and Biotechnology 76, 573-578.

Ince BK, Selcuk A, Ince O. 2002. Effect of a chemical synthesis—based pharmaceutical wastewater performance, acetoclastic methanogenic activity and microbial population in an upflow anaerobic filter. Journal of Chemical Technology and Biotechnology 77, 711–719.

Larsson DGJ, Pedro de C, Paxeus N. 2007. Effluent from drug manufactures contains extremely high levels of pharmaceuticals. Journal of Hazardous Materials 148, 751–755.

Larsson DGJ, Fick J. 2009. Transparency throughout the production chain — a way to reduce pollution from the manufacturing of pharmaceuticals? Regulatory Toxicology and Pharmacology 53, 161–163.

Lettinga G, Hulshoff P.1991. UASB-process design for various types of waste water. Water Science and Technology 24, 87–107.

Maat DZ, Habets LHA. 1987.The UASB wastewater treatment system: a technological review. Pulp and Paper Canada 88, 60–64.

Maia SA, Ribeiro RA, Amorim LC, Barreiro CJ, Cass BQ, Paula ML, Castro LMP, Tiritana EM.2014. Degradation of fluoroquinolone antibiotics and identification of metabolites/transformation products by liquid chromatography–tandem mass spectrometry. Journal of Chromatography A 1333, 87–98.

Mitra S and Gupta SK. 2014. Pilot-scale treatment of a trichloroethylene rich synthetic wastewater in anaerobic hybrid reactor, with morphological study of the sludge granules. Clean Technologies and Environmental Policy 16, 947-956.

Oktem YA, Ince O, Sallis P. 2008.  Anaerobic treatment of a chemical synthesis-based pharmaceutical wastewater in a hybrid upflow anaerobic sludge blanket reactor. Bioresource Technology 99, 1089–1096.

Oz NA, Ince O, Ince BK, Akarsubasi AT, Eyice O.2003. Microbial population dynamics in an anaerobic CSTR treating a chemical synthesis-based pharmaceutical wastewater. Journal of Environmental Science and Health 38, 2029–2042.

Parry MC, Thuy TC, Dongol S, Karkey A, Vinh H, Nguyen CT, Duy TP, Nga TVT, Campbell IJ, Hoang MVN, Arjyal A, Bhutta AZ, Bhattacharya KS, Agtini DM, Dong B, Canh GD, Naheed A, Wain J, Hien TT, Basnyat B, Ochiai L, Clemens J, Farrar JJ, Dolecek C, Baker S. 2010. Suitable Disk Antimicrobial Susceptibility Breakpoints Defining Salmonella enterica Serovar Typhi Isolates with Reduced Susceptibility to Fluoroquinolones. Antimicrobial Agents and Chemotherapy 54, 5201–5208.

Pico Y, Andreu V. 2007. Fluoroquinolones in soil—risks and challenges. Analytical and Bioanalytical Chemistry 387, 1287–1299.

Preito A, Moder M, Rodil R, Adrian L, Urrea E M.2011.Degradation of the antibiotics norfloxacin and ciprofloxacin by a white-rot fungus and identification of degradation products. Bioresource Technology 102, 10987–10995.

Prakash SM, Gupta SK. 2000. Biodegradation of tetrachloroethylene in up flow anaerobic sludge blanket reactor. Bioresource Technology 72, 47–54.

Saravanane  R,  Murthy  DVS,  Krishnaiah  K. 2001. Treatment of anti-osmotic drug based pharmaceutical effluent in an up-flow anaerobic fluidised-bed system. Waste Management 21, 563-568.

Senta I, Matosic M, Jakopovic KH, Terzic S, Curko J, Mijatovic I, Ahel M. 2011. Removal of antimicrobials using advanced wastewater treatment. Journal of Hazardous Materials 192, 319 – 328.

Singh DG, Gupta CK. 2014. Photo and UV degradation of Ciprofloxacin Antibiotic. International Journal of Current Microbiology and Applied Sciences 3, 641-648.

Vasconcelos TG, Kümmerer K, Henriques DM, Martins AF. 2009. Ciprofloxacin in hospital effluent: Degradation by ozone and photo processes. Journal of Hazardous Materials 169, 1154-1158.

Wetzstein HG, Stadler M, Tichy HV, Dalhoff A, Karl W. 1999. Degradation of ciprofloxacin by basidiomycetes and identification of metabolites generated by the brown rot fungus Gloeophyllum striatum. Applied and Environmental Microbiology 65, 1556–1563.

Wick A, Fink G, Joss A, Siegrist H, Ternes AT. 2009. Fate of beta blockers and psycho-active drugs in conventional wastewater treatment. Water Research 43, 1060–1074.

Witte DB, Dewulf J, Demeestere K, Vyvere VVD, Wispelaere PD, Langenhove HV. 2008. Ozonation of ciprofloxacin in water: HRMS identification of reaction products and pathways. Environmental Science and Technology 42, 4889-4895.

Xie BZEA. 2009. Improvement of the activity of anaerobic sludge by low-intensity ultrasound. Journal of Environmental Management.90, 260–264.

Zaviska F, Drogui P, Grasmick A, Azais A, Héran M. 2013. Nanofiltration membrane bioreactor for removing pharmaceutical compounds. Journal of Membrane Science 429, 121–129.

Zhou MP, Su C, Li B, Qian Y. 2006. Treatment of high-strength pharmaceutical wastewater and removal of antibiotics in anaerobic and aerobic biological treatment processes. Journal of Environmental Engineering 132,129- 136.

Zinatizadeh AAL, Salamatinia B, Zinatizadeh SL, Mohamed AR, Hasnain Isa M. 2007. Palm oil mill effluent digestion in an up-flow anaerobic sludge fixed film bioreactor. International Journal of Environmental Research 1, 264–271.

SUBMIT MANUSCRIPT

Style Switcher

Select Layout
Chose Color
Chose Pattren
Chose Background