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Characterization of Fe3O4 nanoparticles for liquid phase immunoassay using brownian relaxation time and magnetic susceptibility

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Research Paper 01/12/2018
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Characterization of Fe3O4 nanoparticles for liquid phase immunoassay using brownian relaxation time and magnetic susceptibility

Md. Anwarul Kabir Bhuiya, Raihana Ferdaws, Md. Abdul Halim, Takeshi YOSHIDA, Keiji Enpuku, Edmund Soji Otabe
Int. J. Biosci. 13(6), 176-185, December 2018.
DOI: http://dx.doi.org/10.12692/ijb/13.6.176-185
Copyright Statement: Copyright 2018; The Author(s).
License: CC BY-NC 4.0

Abstract

This article describes the detail characterization of the magnetic properties of magnetic markers (Fe3O4) in solution for biosensor application. Frequency dependence of the AC susceptibility and the magnetization curve, which were dominated by the Brownian rotation of the marker, Brownian relaxation time were measured. The effect of the viscosity of the carrier liquid on the AC susceptibility was also clarified. The experimental results were analyzed by the singular value decomposition (SVD) method. The distribution of marker size d was obtained from the frequency dependence of the AC susceptibility.  The distribution of magnetic moment m was obtained from the magnetization curve. The relationship between m and d was also discussed.  The present estimation method using SVD technique will be useful to obtain the distribution of particle size d and magnetic moment m, which are the important parameters of the magnetic marker for biomedical application. We also obtained the distributions of magnetic moment m and anisotropy energy barrier EB, and their relationship. From the obtained result, we could classify the particles into three types: Type-I particles with very small m and very short τN, Type-II particles with medium values of m and τN, and Type-III particles with large m and very long τN.

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  1. Phys. D: Appl. Phys. 36 (2003) R167–R181.
  2. Handbook of Magnetic Nanoparticles. Sergey P. Gubin.
  3. A. Pankhurst, N. K. T. Thanh, S. K. Jones, and J. Dobson: J. Phys. D: Appl. Phys. 42 (2009) 224001.
  4. C. Berry: J. Phys. D: Appl. Phys. 42 (2009) 224003.
  5. Lu, F. Ibraimi, D. Kriz, and K. Kriz: Biosens. Bioelectron. 21 (2006) 2248.
  6. J. Chiu, H. E. Horng, J. J. Chien, S. H. Liao, C. H. Chen, B. Y. Shih, C. C. Yang, C. L. Lee, T. F. Chen, S. Y. Yang, C. Y. Hong, and H. C. Yang: IEEE Trans. Appl. Supercond. 21 (2011) 477.
  7. Grossman, W. Myers, V. Vreeland, R. Bruehl, M. D. Alper, C. R. Bertozzi, and J. Clarke: PNAS U.S.A. 101 (2003) 129.
  8. Néel, C. R. Hebd. Seances Acad. Sci. 228, 664 (1949); Ann. Géophys. 5, 99 (1949).
  9. F. Brown, Phys. Rev. 130, 1677 (1963).
  10. Eberbeck D, Bergemann C, Hartwig S, Steinhoff U and Trahms L 2005 Binding kinetics of magnetic nanoparticles on latex beads and yeast cells studied by magnetorelaxometry Magn. Magn. Mater. 289 435–8.
  11. Enpuku K, Kuroda D, Ohba A, Yang T Q, Yoshinaga K, Nakahara T, Kuma H and Hamasaki N 2003 Biological immunoassay utilizing magnetic marker and high Tc superconducting quantum interference device magnetometer J. Appl. Phys. 42 L1436–8.
  12. Ludwig F, Maeselein S, Heim E and Schilling M 2005 Magnetorelaxometry of magnetic nanoparticles in Meas. Sci. Technol. 20 (2009) 125802 WLiu et al magnetically unshielded environment utilizing a differential fluxgate arrangement Sci. Instrum. 76 106102.
  13. Rosensweig R E 1985 Ferrohydrodynamic (Cambridge: Cambridge University Press).
  14. Romanus E, Berkov D V, Prass S, Gross C, Weitschies W and Weber P 2003 Determination of energy barrier distributions of magnetic nanoparticles by temperature dependent magnetorelaxometry Nanotechnology 14 1251–4.
  15. Enpuku, T. Tanaka, M. Matsuda, F. Dang, N. Enomoto, J. Hojo, K. Yoshinaga, F. Ludwig, F. Ghaffari, E. Heim, and M. Schilling: J. Appl. Phys. 102 (2007) 054901.
  16. Brown W F Jr 1963 Thermal fluctuations of a single-domain particle Rev. 130 1677–86.
  17. Yuichi Higuchi, Shinobu Uchida, Anwarul Kabir Bhuiya, Takashi Yoshida, and Keiji Enpuku, “Characterization of Magnetic Markers for Liquid-Phase Detection of Biological Targets” IEEE TRANSACTIONS ON MAGNETICS, VOL. 49,); 7, July 2013.
  18. Anwarul Kabir Bhuiya, Masaki Asai, Hideki Watanabe, Tomokazu Hirata, Yuichi Higuchi, Takashi Yoshida, and Keiji Enpuku, “Characterization of Magnetic Markers and Sensors for Liquid-Phase Immunoassays Using Brownian Relaxation”. IEEE TRANSACTIONS ON MAGNETICS, VOL. 48,) p2838-2841; 11, NOVEMBER
  19. Anwarul Kabir Bhuiya, Tetsu Mitake, Masaki Asai, Tomoya Ito, Schunichi Chosakabe, Takashi Yoshida, Keiji Enpuku, and Akihiko Kandori, “Liquid-Phase Immunoassays Using Brownian Relaxation of Magnetic Markers”. IEEE TRANSACTIONS ON MAGNETICS, VOL. 47,) p2867-2870; 10, OCTOBER 2011.
  20. Bhuiya, Anwarul Kabir; Yoshida, Takeshi; Enpuku, Keiji, “Characterization of Magnetic Markers for Bio-sensing Application”. Research reports on information science and electrical engineering of Kyushu University 15(2) p77-83; 2010-09-24.
  21. Anwarul Kabir BHUIYA, Masaki ASAI, Takashi YOSHIDA and Keiji ENPUKU, “Magnetic Sensor Based Liquid-Phase Immunoassays for the Detection of Biological Targets”. Research reports on information science and electrical engineering of Kyushu University 16(2) p45-50; 2011-09-26.
  22. Enpuku et al., “Characterization of Magnetic Markers for Liquid-Phase Immunoassays Using Brownian Relaxation”, Jpn. J. Appl. Phys., 51, 023002, 2012.

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