Welcome to International Network for Natural Sciences | INNSpub

Paper Details

Research Paper | August 1, 2020

| Download 1

Characterization of inflammatory syndrome in smokers, from C-Reactive protein and erythrocytes sedimentation rate measurements

Hourfil-Gabin Ntougou Assoumou, Gylis Steler Mbebiyangh Yenga, Gontran Nsi Akoue, Joël-Fleury Djoba-Siawaya

Key Words:

Int. J. Biomol. & Biomed.11(1), 8-14, August 2020


IJBB 2020 [Generate Certificate]


A local inflammatory syndrome is characterized by a classic semiological tetrad: pain, swelling, redness and heat. These signs are easily observed when the inflammation concerns the skin or an adjacent tissue. Throughout this study, the aim was to characterize chronic inflammation in smokers using two parameters, rate of erythrocytes sedimentation (RES) and C – reactive protein (CRP). Our study was done on a sample of 35 smoking subjects, composed of men and women. The CRP measurement o was carried out using a CRP-Latex agglutination test which detects only serum CRP levels around 6mg/L. The technique used for the RES measurement is that of Westergreen. From the results, we observed that 31% of our sample presented a positive CRP and a high RES against 40% having regular CRP and RES. The gender of the subject did not play a role in the results obtained. On the other hand, a significant difference (p = 0.031) in CRP was observed between subjects with normal RES and those with high RES. Therefore, these results make it difficult to confirm that RES and CRP can be used as reliable markers for the characterization of inflammation linked to smoking.


Copyright © 2020
By Authors and International Network for
Natural Sciences (INNSPUB)
This article is published under the terms of the Creative
Commons Attribution Liscense 4.0

Characterization of inflammatory syndrome in smokers, from C-Reactive protein and erythrocytes sedimentation rate measurements

Aldaham S, Foote JA, Chow HH, Hakim IA. 2015. Smoking Status Effect on Inflammatory Markers in a Randomized Trial of Current and Former Heavy Smokers. International Journal of Inflammation. 439396. DOI: 10.1155/2015/439396.

Asthana A, Johnson HM, Piper ME, Fiore MC, Baker TB, Stein JH. 2010. Effects of smoking intensity and cessation on inflammatory markers in a large cohort of active smokers. American Heart Journal. Sep 160(3), 458-63.

Beaudeux Jean-Louis, Durand. 2011. Geneviève. Biochimie médicale – Marqueurs actuels et perspectives (2e Ed.), Page 102.

Biomaghreb. 2007. CRP LATEX Détection sérologique sur particules de Latex de la proteïne C Réactive file:///C:/Users/Gabin/Documents/Downloads/Documents/CRP%20latex.pdf, Dec.

Buess T, Ludwig C. 1995. [Diagnostic value of C-reactive protein in comparison with erythrocyte sedimentation as routine admission diagnostic test]. Schweiz Med Wochenschr. Jan 28 125(4), 120-4.

Kawada T. 2015. Relationships between the smoking status and plasma fibrinogen, white blood cell count and serum C-reactive protein in Japanese workers. Diabetes Metabolic Syndrome 9, 180-182. DOI: 10.1016/j.dsx.2015.02.010.

Lecours N, Almeida G, Abdallah J. 2012. Environmental health impact of tobacco farming: a review of literature. Tobacco Control 21, 191-6.

Litao MK, Kamat D. 2014. Erythrocyte sedimentation rate and C-reactive protein: how best to use them in clinical practice. Pediatrics Annals. Oct 43(10), 417-20.

NCCLS. 2000. Reference and Selected Procedure for the Erythrocyte Sedimentation Rate (ESR) Test; Approved Standard—Fourth Edition. NCCLS document H2-A4 (ISBN 1-56238-424-4). NCCLS, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898, USA.

Ohsawa M, Okayama A, Nakamura M, Onoda T, Kato K, Itai K, Yoshida Y, Ogawa A, Kawamura K, Hiramori K. 2005. CRP levels are elevated in smokers but unrelated to the number of cigarettes and are decreased by long-term smoking cessation in male smokers. Preventive Medicine. Aug 41(2), 651-6. DOI: 10.1016/j.ypmed.2005.02.002.

Olivier Chenillot. 2000. CRP, haptoglobine, orosomucoïde: variations biologiques et valeurs de références, relation entre CRP et risque cardiovasculaire. Sciences pharmaceutiques.. https://hal.univ-lorraine.fr/hal-01738859.

Pampel F. 2008. Tobacco use in sub-Sahara Africa: Estimates from the demographic health surveys. Social Science & Medicine 66(8), 1772-1783.

Peltzer N. 2011. Early smoking initiation and associated factors among in-school male and female adolescents in seven African countries. African Health Sciences 11(3), 320-328.


Style Switcher

Select Layout
Chose Color
Chose Pattren
Chose Background