Chemical composition and bilogical effects of essential oil of Artemisia judaica an endemic plant from central Sahara of Algeria Hoggar

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Research Paper 01/01/2017
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Chemical composition and bilogical effects of essential oil of Artemisia judaica an endemic plant from central Sahara of Algeria Hoggar

Ramdane Farah, El Ouassis Dahmane, Hammami Madjdi, Essid Rym, Sobti Amira, Hrizat Nour el Houda, Ben Amara Selma, Fares Nadia, Hadj Mahammed Mahfoud, Ould Hadj Mohamed Didi, Limam Ferid
Int. J. Biosci.10( 1), 16-23, January 2017.
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The medicinal plants contain many secondary metabolites that are gifted of different biologic activities as antiparasital, antimicrobial or antioxidant proprieties. Essential oil extracted from dried aerial parts of Artemisia judaica harvested at central Sahara of Algeria Hoggar, was analysed by gas chromatography (GC-FID) and coupled to mass spectrometry (GC-MS).  Thirty one compounds were identified, representing 88.98%   of the total oil. The major constituents of essential oil were piperitone 66.17%, ethyl cinnamate isomer 6.11% and E-Longipinane 2.55%. The essential oil was tested for radical-scavenging ability using the stable 2,2-diphenylpicrylhydrazyl (DPPH) radical. Antimicrobial and antileishmanail activities of the oil were evaluated against Gram positive and negative bacteria and tow species of leishmania:    Lieshmania major and Leishmania infantum promastigotes respectively. This preliminary study confirmed in part the use of this plant in Sahara folkloric medicine of Algeria, however further investigations into its active constituents and mechanisms of action are needed.


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