Chemical composition, antibacterial and antifungal activities of Azadirachta indica and Mentha spicata L. leave essential oils

Paper Details

Research Paper 01/09/2019
Views (960)
current_issue_feature_image
publication_file

Chemical composition, antibacterial and antifungal activities of Azadirachta indica and Mentha spicata L. leave essential oils

Kashif Ahmed, Anjum Ayub, Muhammad Umar bin Aamir
Int. J. Biosci. 15(3), 478-482, September 2019.
Copyright Statement: Copyright 2019; The Author(s).
License: CC BY-NC 4.0

Abstract

The current workout investigated the chemical symphony and bioactivities of essential oils of Azadirachta indica and Mentha spicata. The essential oils of both herbs were acquired by soxhlet extraction apparatus and a brief chemical examination was conducted by gas chromatography-mass spectrometry (GC-MS) and GC (gas chromatography). Total 13 constituents from the essential oils of Azadirachta indica had been identified among them the major components are 11-octadecanoic acid methyl ester (87.76%), docosanoic acid (4.93%) and 9-octadecanoic acid ethyl ester (3%). Sixteen constituents from Mentha spicata essential oils were also observed among them the major ones are E-Piperitol (42.68%), Caryophyllene oxide (7.79%), 4-terpinol (4.39%), octanoic acid (4.24%), Ascaidole (3.8%), Carvacrol (3.3%), Anethole (3.2%), bicyclo-germacene (2.75%), Caryophyllene (2.73%), Thymol (1.99%), 2-decadienal (1.64%), D-carvone (1.58%), Piperitol (1.38%) and Linollyl acetate (1.34%). The essential oils were screened for their antimicrobial activities. The essential oil of Azadirachta indica was active against 5 Gram positive and 2 Gram negative bacteria showed activity against 1 fungi. Similarly mentha spicata essential oils were also active against 3 Gram positive and 2 Gram negative bacteria.

Ayub A, Tauseef S, Zehra SQ, Begum S, Siddiqui BS, Ahmed A. 2017. Antimicrobial activity of Lantana camara Linn. Fuuast journal of biology 7, 127-130.

Bajaj S, Urooj A, Prabhasankar P. 2016. Antioxidative Properties of Mint (Mentha Spicata L.) and its Application in Biscuits. Current Research in Nutrition and Food Science 4, 209-216.

Bandyopadhyay U, Biswas K, Sengupta A. 2004. Clinical studies on the effect of Neem (Azadirachta indica) barks extract on gastric secretion and gastro duodenal ulcer. Life Sciences 75, 2867-2878.

Ebong PE, Atangwho IJ, Eyong EU, Egbung GE. 2008. The antidiabetic efficacy of combined extracts from two continental plants: Azadirachta indica (A. Juss) (Neem) and Vernonia amygdalina (Del.) (African Bitter Leaf). The American Journal of Biochemistry and Biotechnology 4, 239-244.

Mahapatra S, Young CYF, Kohli M. 2012. Antiangiogenic effects and therapeutic targets of Azadirachta indica leaf extract in endothelial cells. Evidence-Based Complementary and Alternative Medicine 2012, 1-14.

Patwary MDHY, Nusrat YN, Mohammad S, Rajib B, Biplab KD. 2013. Analgesic, Anti-Inflammatory and Antipyretic Effect of Mentha spicata (Spearmint). British Journal of Pharmaceutical Resistance 3, 854-864.

Paul R, Prasad M, Sah NK. 2011. Anticancer biology of Azadirachta indica L (neem): a mini review. Cancer Biology and Therapy 12, 467-476.

Prashanth GK, Krishnaiah GM. 2014. Chemical composition of the leaves of Azadirachta Indica Linn (Neem). International journal of advancement in engineering technology management and applied sciences 1, 21-31.

Prieto P, Pineda M, Aguilar M. 1999. Activity of a standardized neem (Azadirachta Indica) seed extract on the rodent malaria parasite plasmodium berghei. Analytical Biochemistry 269, 337-341.

Sultana B, Anwar F, Przybylski R. 2007. Antioxidant activity of phenolic components present in barks of Azadirachta indica, Terminalia Arjuna, Acacia nilotica, and Eugenia jambolana. Food Chemistry 104, 1106-1114.

Wang J, Wu D, Wei CS. 2002. Structure activity relationship of reversibly lipidized peptides: studies of Fatty acid-Desmopressin conjugates. Pharmaceutical Resistance 19, 609-614.

Yasser S. 2015. Chemical Composition and In Vitro Antibacterial Activity of Mentha spicata Essential Oil against Common Food-Borne Pathogenic Bacteria. Journal of Pathogens 2015, 1-5.

Related Articles

Effects of supplementary irrigation, organic and mineral fertilizers on the agrophysiological performance of three varieties of millet (Pennisetum glaucum L. R. Br.) in Burkina Faso

Hadara Nomba Ouedraogo*, Ahmed Traore, Ouènian Zibihako, Adama Pascal Kihindo, Int. J. Biosci. 29(1), 200-210, July 2026.

Physico-chemical composition and phytochemical screening of cocoa mass purchased commercially in Abidjan (Côte d’Ivoire)

Attoh Hyacinthe Anon*, Hermann Fourier Atta Anno, Nyamien Yves Bleouh Jean, Fagbohoun Jean Bedel, Kouassi kouame Henri Joel, Patrice Lucien Kouamé, Int. J. Biosci. 29(1), 188-199, July 2026.

Survey of swine diseases and treatment approaches in Korhogo subprefecture, northern of Côte d’Ivoire

Kouhana Soro*, Ghislaine Sègbédji Théodora Atchade, Koffi Jules Gossé, Nea Yves Noma, Assanvo Simon-Pierre N’guetta, Int. J. Biosci. 29(1), 171-179, July 2026.

Length-weight relationship and population structure of pool barb (Puntius sophore) from Jashore, Bangladesh

Md. Almamun Farid*, Abu Shale Md. Nasim, Int. J. Biosci. 29(1), 160-170, July 2026.

Role of the Kogle-zanga biopesticide in improving amaranth leaf production in Loumbila

Drabo Samuel Fogné*, Nikiéma Dominique, Zézouma Anselme Dao, Romba Rahim, Sedogo Sanata, Gnankine Olivier, Int. J. Biosci. 29(1), 149-159, July 2026.

Systematic review evaluating locally sourced food resources alternatives to standard milk-based ready-to-use therapeutic food

Folachodé Ulrich Gildas Akogou*, Janvier Mêlégnonfan Kindossi, Dona Gildas Hippolyte Anihouvi, Gamèli Justin Gandeho, Carole Nadia Adjouavi Sossa – Vihotogbé, Franck Hongbété, Polycarpe Kayodé, Int. J. Biosci. 29(1), 138-148, July 2026.

Clinical importance of stem cells in T2D treatment: A systematic review

Mirza Masroor Ali Beg*, Nilam Bhasker, Tridiv Katiyar, Amar Chandra Sharma, Int. J. Biosci. 29(1), 130-137, July 2026.