Chemical composition, antibacterial and antifungal activities of Azadirachta indica and Mentha spicata L. leave essential oils

Paper Details

Research Paper 01/09/2019
Views (987)
current_issue_feature_image
publication_file

Chemical composition, antibacterial and antifungal activities of Azadirachta indica and Mentha spicata L. leave essential oils

Kashif Ahmed, Anjum Ayub, Muhammad Umar bin Aamir
Int. J. Biosci. 15(3), 478-482, September 2019.
Copyright Statement: Copyright 2019; The Author(s).
License: CC BY-NC 4.0

Abstract

The current workout investigated the chemical symphony and bioactivities of essential oils of Azadirachta indica and Mentha spicata. The essential oils of both herbs were acquired by soxhlet extraction apparatus and a brief chemical examination was conducted by gas chromatography-mass spectrometry (GC-MS) and GC (gas chromatography). Total 13 constituents from the essential oils of Azadirachta indica had been identified among them the major components are 11-octadecanoic acid methyl ester (87.76%), docosanoic acid (4.93%) and 9-octadecanoic acid ethyl ester (3%). Sixteen constituents from Mentha spicata essential oils were also observed among them the major ones are E-Piperitol (42.68%), Caryophyllene oxide (7.79%), 4-terpinol (4.39%), octanoic acid (4.24%), Ascaidole (3.8%), Carvacrol (3.3%), Anethole (3.2%), bicyclo-germacene (2.75%), Caryophyllene (2.73%), Thymol (1.99%), 2-decadienal (1.64%), D-carvone (1.58%), Piperitol (1.38%) and Linollyl acetate (1.34%). The essential oils were screened for their antimicrobial activities. The essential oil of Azadirachta indica was active against 5 Gram positive and 2 Gram negative bacteria showed activity against 1 fungi. Similarly mentha spicata essential oils were also active against 3 Gram positive and 2 Gram negative bacteria.

Ayub A, Tauseef S, Zehra SQ, Begum S, Siddiqui BS, Ahmed A. 2017. Antimicrobial activity of Lantana camara Linn. Fuuast journal of biology 7, 127-130.

Bajaj S, Urooj A, Prabhasankar P. 2016. Antioxidative Properties of Mint (Mentha Spicata L.) and its Application in Biscuits. Current Research in Nutrition and Food Science 4, 209-216.

Bandyopadhyay U, Biswas K, Sengupta A. 2004. Clinical studies on the effect of Neem (Azadirachta indica) barks extract on gastric secretion and gastro duodenal ulcer. Life Sciences 75, 2867-2878.

Ebong PE, Atangwho IJ, Eyong EU, Egbung GE. 2008. The antidiabetic efficacy of combined extracts from two continental plants: Azadirachta indica (A. Juss) (Neem) and Vernonia amygdalina (Del.) (African Bitter Leaf). The American Journal of Biochemistry and Biotechnology 4, 239-244.

Mahapatra S, Young CYF, Kohli M. 2012. Antiangiogenic effects and therapeutic targets of Azadirachta indica leaf extract in endothelial cells. Evidence-Based Complementary and Alternative Medicine 2012, 1-14.

Patwary MDHY, Nusrat YN, Mohammad S, Rajib B, Biplab KD. 2013. Analgesic, Anti-Inflammatory and Antipyretic Effect of Mentha spicata (Spearmint). British Journal of Pharmaceutical Resistance 3, 854-864.

Paul R, Prasad M, Sah NK. 2011. Anticancer biology of Azadirachta indica L (neem): a mini review. Cancer Biology and Therapy 12, 467-476.

Prashanth GK, Krishnaiah GM. 2014. Chemical composition of the leaves of Azadirachta Indica Linn (Neem). International journal of advancement in engineering technology management and applied sciences 1, 21-31.

Prieto P, Pineda M, Aguilar M. 1999. Activity of a standardized neem (Azadirachta Indica) seed extract on the rodent malaria parasite plasmodium berghei. Analytical Biochemistry 269, 337-341.

Sultana B, Anwar F, Przybylski R. 2007. Antioxidant activity of phenolic components present in barks of Azadirachta indica, Terminalia Arjuna, Acacia nilotica, and Eugenia jambolana. Food Chemistry 104, 1106-1114.

Wang J, Wu D, Wei CS. 2002. Structure activity relationship of reversibly lipidized peptides: studies of Fatty acid-Desmopressin conjugates. Pharmaceutical Resistance 19, 609-614.

Yasser S. 2015. Chemical Composition and In Vitro Antibacterial Activity of Mentha spicata Essential Oil against Common Food-Borne Pathogenic Bacteria. Journal of Pathogens 2015, 1-5.

Related Articles

Stabilization of cashew apple juice with chitosan: clarification and microbiological quality

Kokora Aya Philomène*, Coulibaly Adama, Cissé Mohamed, Coulibaly Bintou, Konan N’guessan Ysidor, Godi Henri Marius Biego, Int. J. Biosci. 29(2), 76-88, August 2026.

Implementation and evaluation of limited face to face classes: basis for adoption of health and safety manual

Christian Jude B. Calunsag*, Int. J. Biosci. 29(2), 65-75, August 2026.

Baseline characterization of farming systems in the province of Bassitenga in Burkina Faso

Boly Ismaël Ardho*, Traoré Mamadou, Hema Alain Sabiriba, Sory Lallé Daouda, Int. J. Biosci. 29(2), 54-64, August 2026.

Zootechnical performance and economic profitability of sasso broiler chickens reared under a semi-automatic production system in Burkina Faso

Bernadette Yougbaré*, Arnaud Stéphane Rayangnéwêndé Tapsoba, Fatogoman Téophile Sanou, Clément Kaboré, Amadou Traoré, Int. J. Biosci. 29(2), 35-44, August 2026.

Factors influencing the use of Mucuna pruriens as food in Benin, West Africa

Yves Boladé Djimba, Janvier Mêlégnonfan Kindossi*, Folachodé Ulrich Gildas Akogou, Ephraïm Olouwafemi Biao, Jacques Agangni, Kokou Mensah Adjangba, Ogouyôm Herbert Iko Afé, Franck Hongbété, Rodrigue V. Cao Diogo, Int. J. Biosci. 29(2), 19-34, August 2026.

Contribution to the inventorier and establishment of a collection of agricultural entomofauna from the Niayes area of Dakar

Mamecor Faye*, Amy Collé Guèye, Coumba Gning, Lamine Konaté, Mbacké Sembène, Int. J. Biosci. 29(2), 10-18, August 2026.

Assessment of the trophic ecology and variation in the natural diet of an anuran amphibian species (Afrixalus dorsalis) in the Wetlands of the Ehotilé Islands (Ivory Coast)

Beh Romaric Konate*, Amani Reine Élisabeth Kouadio, Louis César Agou, Enoutchy Fabrice Bouah, N'Guessan Ludovic Yao, Etilé Raphaël N’doua, Int. J. Biosci. 29(2), 1-9, August 2026.