Coenzyme q10: A multifaceted therapeutic molecule in neurological, cardiovascular, and reproductive health

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Review Paper 05/08/2026
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Coenzyme q10: A multifaceted therapeutic molecule in neurological, cardiovascular, and reproductive health

Vinita Tepan, Anjali Sain, Imran Khan, Farah Syed*
Int. J. Biomol. Biomed. 23(2), 1-22, August 2026.
Copyright Statement: Copyright 2026; The Author(s).
License: CC BY-NC 4.0

Abstract

Coenzyme Q10 (ubiquinone), is a lipid-soluble molecule derived primarily from endogenous synthesis. It plays an essential role in the electron-transport chain of mitochondrial respiratory chain. It also works as an antioxidant and is often used as an anti-aging supplement. It can also help with the symptoms of many health problems that are linked to mitochondrial malfunction. Evidence indicates that CoQ10 supplementation may alleviate neurodegenerative processes, enhance reproductive results in both sexes, and promote cardiovascular function. This review is to deliver a thorough examination of the existing evidence about the therapeutic uses of CoQ10, emphasising its functions in neuroprotection, fertility, and cardiovascular well-being. Its translational potential will be evaluated by looking at mechanistic discoveries, evidence from clinical trials, and where the field is headed in the future. Although promising, additional large-scale, randomised controlled trials are required to formulate definite clinical guidelines.

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