Commiphora swynnertonii (BURTT) as a potential new alternative for the management of tick infestation in Tanzania

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Review Paper 01/03/2018
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Commiphora swynnertonii (BURTT) as a potential new alternative for the management of tick infestation in Tanzania

Disela Edwin, Paul Erasto, Sylvester Temba, Musa Chacha
J. Bio. Env. Sci.12( 3), 181-191, March 2018.
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The evolution of tick resistance to synthetic acaricides has given rise to the need for new scientific investigations on alternative ways to control tick infestation. In this esteems, various studies on plant extracts have been developed aiming to identify new compounds that are able to control ticks. In this context, Commiphora swynnertonii exudates may be a promising alternative in the management of ticks. Commiphora swynnertonii is the flowering plant in the family Burseraceae and it is popularly known as “Oltemwai” by Maasai people of Tanzania. In this review we highlight four major tick-borne diseases which are of economic importance in Tanzania. The use of synthetic acaricides and their challenges brought to the environment are also discussed in this review. Commiphora swynnertonii appears to be as a promising alternative in the control of tick infestation and other arthropods of economic importance.


Adam ME, Selim SA. 2013. Antimicrobial activity of essential oil and methanol extract from Commiphora molmol (Engl.) resin. International Journal of Current Microbiology and Applied Sciences 2, 1-6.

Akhtar MS, Iqbal Z, Khan MN, Lateef M. 2000. Anthelmintic activity of medicinal plants with particular reference to their use in animals in the Indo-Pakistan subcontinent. Small Ruminant Research 38, 99-107.

Akor JS, Anjorin TS. 2009. Phytochemical and antimicrobial studies of Commiphora africana root extracts. International Journal Agriculture and Biology 11, 795-797.

Al-Harbi MM, Qureshi S, Raza M, Ahmed MM, Afzal M, Shah AH. 1997. Gastric antiulcer and cytoprotective effect of Commiphora molmol in rats. Journal of Ethnopharmacology 55, 141-150.

Aliyu R, Adebayo AH, Gatsing D, Garba IH. 2007. The effects of leaf extract pharmacology of Commiphora africana (Burseraceae) on rat liver and kidney function. Journal of Pharmacology and Toxicology 2, 373-379.

All AS, AIi M. 2007. Antibacterial Activity of Commiphora quadricincta from Saudi Arabia. Journal of King Saud University 1, 1420-2000.

Andreotti R, Garcia MV, Matias J, Barros JC, Cunha RC. 2014. Tagetes minuta Linnaeus (Asteraceae) as a Potential New Alternative for the Mitigation of Tick Infestation. Medicinal and Aromatic Plants 3.

Aydin MF, Aktas M, Dumanli, N. 2015. Molecular identification of Theileria and Babesia in ticks collected from sheep and goats in the Black Sea region of Turkey. Parasitology research 114, 65-69.

Bakari GG, Max RA, Mdegela HR, Phiri EC, Mtambo MM. 2012. Effect of crude extracts from Commiphora swynnertonii (Burtt) against selected microbes of animal health importance. Journal of Medicinal Plants Research 6, 1795-1799.

Baker JFA, Shaw RD. 1965. Toxaphene and lindane resistance in Rhipicephalus appendiculatus, the brown ear tick of equatorial and southern Africa. Journal of the South African Veterinary Association 36, 321-330.

Balandrin MF, Klocke JA, Wurtele ES, Bollinger WH. 1985. Natural plant chemicals: sources of industrial and medicinal materials. Science 228, 1154-1160.

Barata L. 2005. Empirismo e ciência: fonte de novos fitom edicamentos. Ciência e Cultura 57, 4-5.

Bissinger BW, Roe RM. 2010. Tick repellents: Past, present, and future. Pesticide Biochemistry and Physiology 96, 63-79.

Bock R, Jackson L, de Vos A, Jorgensen W. 2004. Babesiosis of cattle. Parasitology 129, 247-269.

Chagas ACS, Leite RC, Furlong J, Prates, HT, et al. 2003. Sensibilidade do carrapato Boophilus microplus a solventes. Ciência Rural 33, 109-114.

Crampton AL, Baxter GD, Barker SC. 1999. Identification and characterization of a cytochrome P450 gene and processed pseudogene from an arachnid: the cattle tick, Boophilus microplus. Insect Biochemistry and Molecular Biology 29, 377-384.

Dalgliesh RJ, Jorgensen W, De Vos AJ. 1990. Australian frozen vaccines for the control of babesiosis and anaplasmosis in cattle- A review. Tropical Animal Health and Production 22, 44-52.

De la Fuente J, Torina A, Naranjo V, Caracappa S, Di Marco V, Alongi A, Russo M, Maggio AR, Kocan KM. 2005. Infection with Anaplasma phagocytophilum in a seronegative patient in Sicily, Italy: case report. Annals of clinical microbiology and antimicrobials 4, 15-18.

Dellavalle PD, Cabrera A, Alem D, Larrañaga P, Ferreira F, Dalla Rizza M. 2011. Antifungal activity of medicinal plant extracts against phytopathogenic fungus Alternaria spp. Chilean Journal of Agricultural Research 71, 231-239.

Edwin D, Erasto P, Temba S, Chacha M. 2017. Repellency activity of Commiphora swynnertonii exudates against Rhipicephalus appendiculatus larvae. Journal of Biodiversity and Environmental Sciences 11, 281-286.

Eriks IS, Stiller D, Palmer GH. 1993. Impact of persistent Anaplasma marginale rickettsemia on tick infection and transmission. Journal of Clinical Microbiology 31, 2091-6.

Ezekiel I, Mabrouk MA, Ayo JO. 2010. Study of the Effect of Hydro-Ethanolic Extract of Commiphora africana (Stem-bark) on Inflammation and Pain in Rodents. Asian Journal of Medical Sciences 2, 81-84.

FAO. 1984. Ticks and tick-borne disease control: A practical field manual, Food and Agriculture Organization of the United Nations 1-299.

FAO. 2004. Resistance management and integrated parasites control in ruminants 25-77.

Fatope MO, Al-Burtomani SKS, Ochei JO, Abdulnour AO, Al-Kindy SMZ, Takeda Y. 2003. Muscanone: a 3-O-(1″, 8″, 14″- trimethylhexadecanyl) naringenin from Commiphora wightii. Phytochemistry 62, 1251-1255.

Fernandes FF. 2001. Toxicological effects and resistance to pyrethroids in Boophilus microplus from Goias, Brazil. Arquivo Brasileiro de Medicina Veterinária e Zootecnia 53, 538-543.

Fyumagwa RD, Sudi FF, Bahari M. 2004. Diseases status in livestock wildlife interfaces in Tanzania. In Proceedings of the WDA-Africa and Middle East Section Annual Conference, Abu Dhabi December 11.

George JE, Pound JM, Davey RB. 2004. Chemical control of ticks on cattle and the resistance of these parasites to acaricides. Parasitology 129, 353-366.

George JE. 2000. Present and future technologies for tick control. Annals of the New York Academy of Sciences 916, 583-588.

Ghani A. 2013. Herbal medicines: Present status, future prospects. Pharma World 6, 59-62.

Guglielmone AA, Beati L, Barros-Battesti DM, Labruna MB, Nava S, et al. 2006. Ticks (Ixodidae) on humans in South America. Experimental and Applied Acarology 40, 83-100.

Guglielmone AA, Robbins RG, Apanaskevich DA, Petney TN, Estrada-Peña A. et al. 2010. The Argasidae, Ixodidae and Nuttalliellidae (Acari: Ixodidae) of the world: a list of valid species names. Zootaxa 2528, 1-28.

Haffor AS. 2010. Effect of myrrh (Commiphora molmol) on leukocyte levels before and during healing from gastric ulcer or skin injury. Journal of Immunotoxicology 7, 68-75.

Hanus LO, Rezanka T, Dembitsky VM, Moussaieff A. 2005. Myrrh- Commiphora, chemistry. Biomedical Paper 149, 3-28.

Iqbal RZ, Song-hua HU, Wan-jun C, Chen-wen X. 2006. Importance of ticks and their chemical and immunological control in livestock. Journal of Zhejiang University SCIENCE B 7, 912-921.

Jongejan F, Uilenberg G. 2004. The global importance of ticks. Parasitology 129, 3-14.

Kalala W, Magadula J, Mdegela H. 2014. Evaluating Acaricidal Activity of Commiphora swynertonii Burrt. bark Exudate against common Ticks in Tanzania. International Journal of Herbal Medicine 2, 19-25.

Kalala WM, Magadula JJ, Mdegela RH. 2014. Ethnobotanical use of Commiphora swynertonii Burrt. amongst Dorobo people in Tanzania. Journal of Medicinal Plant Research 8, 820-828.

Kaoneka B, Mollel M, Lyatuu F. 2007. Leaf essential oil composition and tick repellency activity of Commiphora swynnertonii Burtt. Journal of Biological Research- Thessaloniki 8, 213-216

Kaoneka B, Mollel M. 2012. Acaricidal activities of extracts of Commiphora swynnertonii Burtt (Burseraceae), Melia volkensii Gürke, Turraea abyssinica Hochst., Turraea floribunda Hochst and Turraea cornucopia Styles & F. White (Meliaceae) against the brown ear tick Rhipicephalus sp. Huria: Journal of the Open University of Tanzania 10, 24-33.

Kissmann KG, Groth D. 1992. Plantas infestantes e nocivas. Ludwigshaven: BASF 2, 355-356.

Kivaria FM, Noordhuizen JPTM, Msami HM. 2007. Risk factors associated with the incidence rate of clinical mastitis in smallholder dairy cows in the Dar es Salaam region of Tanzania. Veterinary Journal 173, 623-629.

Kivaria FM. 2006. Estimated direct economic costs associated with tick-borne diseases on cattle in Tanzania. Tropical Animal Health and Production 38, 291-299.

Kumari R, Meyyappan A, Nand D, Bikram KA, Avik AC, Palanisamy S, Subbaiah L, Venkatachalam SG, Joydeep M, Santu B, Parasuraman J. 2011. Antioxidant and antibacterial activities of bark extracts from Commiphora berryi and Commiphora caudata. Natural Product Research 1–9.

Latif AA, Walker AR. 2004. An introduction to the biology and control of ticks in Africa. ICTTD-2 project 1-29.

Lawrence JA, Norval RA, Uilenberg G. 1983. Rhipicephalus zambeziensis as a vector of bovine theileriae. Tropical animal health and production 15, 39-42.

Lessard P, Sorensen M, Norval RAI, Perry BD, Dolan TT, Burrill AL, Eplattenier R, Grootenhuis JG, Irvin AD. 1988. Geographical information systems in the estimation of East Coast fever risk to African livestock. Acta Veterinaria Scandinavica 84, 234-236.

Lounsbury CP. 1904. Transmission of African Coast fever. Agricultural Journal of the Cape of Good Hope 24, 428-432.

Lynen G, Zeman P, Bakuname C, Di Giulio G, Mtui P, Sanka P, Jongejan F. 2007. Cattle ticks of the genera Rhipicephalus and Amblyomma of economic importance in Tanzania: distribution assessed with GIS based on an extensive field survey. Experimental and Applied Acarology 43, 303-19.

Lynen G, Zeman P, Bakuname C, Di Giulio G, Mtui P, Sanka P, Jongejan F. 2007. Cattle ticks of the genera Rhipicephalus and Amblyomma of economic importance in Tanzania: distribution assessed with GIS based on an extensive field survey. Experimental and Applied Acarology 43, 303-19.

Mamiro KA, Magwisha HB, Rukambile EJ, Ruheta MR, Kimboka EJ, Malulu DJ, Malele II. 2016. Occurrence of Ticks in Cattle in the New Pastoral Farming Areas in Rufiji District, Tanzania. Journal of veterinary medicine 2016.

Mbassa GK, Mgongo FO, Melau LS, Mlangwa JE, Silayo RS, Bimbita EN, Hayghaimo AA, Mbiha ER. 2009. A financing system for the control of tick-borne diseases in pastoral herds: The Kambala (Tanzania) model. Livestock Research for Rural Development 21.

Mcleod R, Kristjanson P. 1999. Economic impact of ticks and tick-borne diseases to livestock in Africa, Asia and Australia. Report to the International Livestock Research Institute, Nairobi Kenya.

Mkangara M, Chacha M, Erasto P. 2014. Acaricidal Activity of Commiphora swynnertonii (Burtt) Stem Bark Extracts against adult Rhipicephalus appendiculatus Newman and Amblyomma variegatum. American Journal of Research Communication 2, 82-92.

Mkolo MN, Magano SR. 2007. Repellent effects of the essential oil of Lavendula angustifolia against adults of Hyalomma marginatum rufipes. Journal of the South African Veterinary Association 78, 149-152.

Mtei BJ, Msami HM. 1996. Reflection on current animal health status in Tanzania. Tanzania Veterinary Journal 16, 45-58.

Mukhebi AW, Perry BD, Kruska R. 1992. Estimated economics of theileriosis control in Africa. Preventive Veterinary Medicine 12, 73-85.

Muraguri GR, Kiara HK, McHardy N. 1999. Treatment of East Coast fever: a comparison of parvaquone and buparvaquone. Veterinary Parasitology 87, 25-37.

Nagagi YP, Silayo RS, Luziga C Kweka EJ. 2017. In vivo effect of Commiphora swynnertonii ethanolic extracts on Trypanosoma congolense and selected immunological components in mice. BMC complementary and alternative medicine 17, 275.

Neitz WO. 1955. Corridor disease: A fatal form of bovine theileriosis encountered in Zululand. Bulletin of Epizootic Diseases of Africa 3, 121-123.

Norval RAI, Perry BD, Young AS. 1992. The Epidemiology of Theileriosis in Africa Academic Press. Orlando FL.

Nyabayo CT, Matasyoh JC, Mwendia C. 2015. Chemical composition and acaricidal activity of Salvia nilotica essential oil against Rhipicephalus appendiculatus 3, 46-54.

Ocaido M, Muwazi RT, Opuda, JA. 2009. Economic impact of ticks and tick-borne diseases on cattle production systems around Lake Mburo National Park in South Western Uganda. Tropical Animal Health and Production 41, 731-739.

Ogrzewalska M, Pacheco RC, Uezu A, Richtzenhain LJ, Ferreira F. 2009. Ticks (Acari: Ixodidae) infesting birds in an Atlantic rain forest region of Brazil. Journal of Medical Entomology 46, 1225-1229.

Okoh AAEJ, Oyetunde IL, Ibu JO. 1987. Heartwater infection (cowdriosis) in a sitatunga (tragelaphus spekei) in Nigeria. Journal of Wildlife Diseases 23, 211-214.

Olivo CJ, Heimerdinger AZ, Magnos F, Agnolin CA, Meinerz GR. et al. 2009. Extrato aquoso de fumo em corda no controle do carrapato de bovinos. Ciência Rural, Santa Maria 39, 1131-1135.

Olwoch JM, Reyers B, Engelbrecht FA, Erasmus BFN. 2008. Climate change and the tick-borne disease, Theileriosis (East Coast fever) in sub-Saharan Africa. Journal of Arid Environments 72, 108-120.

Onono JO, Wieland B, Rushton J. 2013. Constraints to cattle production in a semiarid pastoral system in Kenya. Tropical Animal Health and Production 45, 1415-1422.

Opdebeeck JP, Wong JY, Jackson LA, Dobson C. 1988. Hereford cattle immunized and protected against Boophilus microplus with soluble and membrane-associated antigens from the midgut of ticks. Parasite Immunology 10, 405-410.

Opiro R, Osinde C, Okello-Onen J, Akol AM. 2013. Tick-repellent properties of four plant species against Rhipicephalus appendiculatus Neumann (Acarina: Ixodidae) tick species. Journal of Agricultural Research and Development 3, 17-21.

Paparozzi ET. 2005. Plant Resins-Chemistry, Evolution Ecology and Ethnobotany. HortScience 40, 508-508.

Paraskeva MP, Van Vuuren RL. Van Zyl HD, Viljoen AM. 2008. In vitro biological activity of selected South African Commiphora species. Journal of Ethnopharmacology 119, 673-679.

Penzhorn BL. 2006. Babesiosis of wild carnivores and ungulates. Veterinary parasitology 138, 11-21.

Provost A, Bezuidenhout JD. 1987. The historical background and global importance of heart water. Journal of Veterinary Research 54, 165-169.

Rafyi A, Maghami G. 1961. Contribution a l’etude de quelques parasites du sang du mouton et de la chevre en Iran et dans les pays voisins. Bulletin – Office International Des Epizooties 65, 1769-1783.

Ramanan C, Ranjith PV, Mehta MJ. Future prospects of herbal medicines in India.

Ristic M, McIntyre I. 1981. Infectious Diseases of Cattle in the Tropics, 1st Edition (Eds.); Martinus Nijhoff Publishers: The Hague 6, 443-468.

Ruffo CK, Birnie A, Tengnäs B. 2002. Edible wild plants of Tanzania. Regional Land Management Unit (RELMA). Technical Handbook Series 27. SIDA. Nairobi, Kenya p. 766.

Sambuta AK, Masola SN. 2006. The efficacy of Commiphora swynnertonii extracts in the control of external parasites in livestock. In Proceedings of First Costech Scientific and Technological Conference Programme, Dar es Salaam, Tanzania Vol. 4243.

Shai LJ, Bizimenyera ES, Bagla V, McGaw LJ, Eloff JN. 2009. Curtisia dentata (Cornaceae) leaf extracts and isolated compounds inhibit motility of parasitic and free-living nematodes. Onderstepoort Journal of Veterinary Research 76, 249-56.

Silva Lima D, Carva Lho JFD, Peixoto M, Blank A, Borges LM, Costa Junior L. 2016. Assessment of the repellent effect of Lippia alba essential oil and major monoterpenes on the cattle tick Rhipicephalus microplus. Medica and Veterinary Entemology 30, 73-77.

Simlinger C. 2005. European Union concerted action on Lyme Borreliosis. EUCALB representatives.

Sindhu Z, Jonsson NN, Iqbal Z. 2003. Discovery of New Ixodicides : from Documentation of Ethno-veterinary Practices to Scientific Validation in Laboratory.

Smith T, Kilborne FL. 1893. Investigations into the nature, causation, and prevention of Texas or southern cattle fever. Vol. 1. US Government Printing Office.

Soromessa T. 2013. Perspective Ecological Phytogeography : A Case Study of Commiphora Species 7522, 93–104.

Van der walt JJA. 1974. A preliminary report on the genus Commiphora in South West Africa. Mapoqua 1, 15-231

Veronez VA, Freitas BZ, Olegário MM, Carvalho WM, Pascoli GV, et al. 2010. Ticks (Acari: ixodidae) within various phytophysiognomies of a cerrado reserve in Uberlândia, Minas Gerais, Brazil. Experimental and Applied Acarology 50, 169-179.

Wesonga FD, Kitala PM, Gathuma JM, Njenga MJ, Ngumi PN. 2010. An assessment of tick-borne diseases constraints to livestock production in a smallholder livestock production system in Machakos District, Kenya.

Zhu N, Rafi MM, DiPaola RS, Xin J, Chin CK, Badmaev V, Ghai G, Rosen RT, Ho CT. 2001. Bio-active constituents from gum guggul (Commiphora wightii). Phytochemistry 56, 723-727.