Int. J. Biosci.17(3), 13-22, September 2020
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in female’s worldwide. Carcinoma of breast is potentially curable disease when treated at early stage. Metastatic breast cancer is essentially incurable disease in spite of the clinical benefits of chemotherapy. Modified radical mastectomy (MRM) or even breast-conserving surgery (BCS) combined with radiotherapy, could achieve local recurrence rates and overall survival rates similar to more invasive approaches. In our study we compared the postoperative complications of BCS and MRM in Early Breast Carcinoma by examininga total of 160 women with stage I and stage II breast carcinoma. We also computed the rate of common complications such as seroma formation and wound infection. This can be helpful in deciding the better technique in terms of less complication rate.
Bhatty I, Ibrahim M, Chaudhry ML. 2004. Complications after modified radical mastectomy in early breast cancer. Pakistan Journal of Medical Sciences 20(2), 125-130.
Cameron AP, Ebbs SR, Wylie F, Baum M. 1988. Suction drainage of the axilla: a prospective randomized trial. British journal of surgery 75(12).
Gonzalez EA, Saltzstein EC, Riedner CS, Nelson BK. 2003. Seroma formation following breast cancer surgery. The breast journal 9(5), 385-388.
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. 2011. Global cancer statistics. CA: a cancer journal for clinicians 61(2), 69-90.
Jemal A, Center MM, DeSantis C, Ward EM. 2010. Global patterns of cancer incidence and mortality rates and trends. Cancer Epidemiology and Prevention Biomarkers 19(8), 1893-1907.
Kayani MS, Zaheer M, Ashraf N, Malik AM. 2008. Morbidity and mortality in breast conservation surgery in early carcinoma breast. Pakistan Armed Forces Medical Journal. 58(3), 253-259.
Krekel NM, Haloua MH, Cardozo AM, de Wit RH, Bosch AM, de Widt-Levert LM, Muller S, van der Veen H, Bergers E, de Klerk ES, Meijer S. 2013. Intraoperative ultrasound guidance for palpable breast cancer excision (COBALT trial): a multicentre, randomised controlled trial. The lancet oncology 14(1), 48-54.
Lanng C, Hoffmann J. 2002. Conservative treatment of wound infection after breast cancer surgery. Ugeskrift for laeger 164(36), 4185-4187.
Lefebvre D, Penel N, Deberles MF, Fournier C. 2000. Incidence and surgical wound infection risk factors in breast cancer surgery. Presse medicale (Paris, France: 1983) 29(35), 1927-1932.
Parveen S, Sarwar G, Khuwaja M, Ahmed R, Nazeer M. 2011. Carcinoma of breast, pattern and presentation in developing countries. Pakistan Journal of Surgery 24, 246-249.
Platt R, Zaleznik DF, Hopkins CC, Dellinger EP, Karchmer AW, Bryan CS, Burke JF, Wikler MA, Marino SK, Holbrook KF, Tosteson TD. 1990. Perioperative antibiotic prophylaxis for herniorrhaphy and breast surgery. New England Journal of Medicine 322(3), 153-160.
Platt R, Zucker JR, Zaleznik DF, Hopkins CC, Dellinger EP, Karchmer AW, Bryan CS, Burke JF, WiklerMA, Marino SK, Holbrook KF. 1993. Perioperative antibiotic prophylaxis and wound infection following breast surgery. Journal of Antimicrobial Chemotherapy 31(suppl B), 43-48.
Porter K, O’Connor S, Rimm E, Lopez M. 1998. Electrocautery as a factor in seroma formation following mastectomy. The American journal of surgery 176(1), 8-11.
Siddiqui MS, Kayani N, Sulaiman S, Hussainy AS, Shah SH, Muzaffar S. 2000. Breast carcinoma in Pakistani females: a morphological study of 572 breast specimens. Journal-Pakistan Medical Association 50(6), 174-176.
Talbot ML, Magarey CJ. 2002. Reduced use of drains following axillary lymphadenectomy for breast cancer. ANZ journal of surgery 72(7), 488-490.
Woodworth PA, McBoyle MF, Helmer SD, Beamer RL. 2000. Seroma formation after breast cancer surgery: incidence and predicting factors/discussions. The American surgeon 66(5), 444.