Curcumin extract nanoparticles: preparation, characterization and antimicrobial effect

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Research Paper 01/03/2020
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Curcumin extract nanoparticles: preparation, characterization and antimicrobial effect

Awatif I Muhammed, Baraa M Thakir, Rana A Kamal, Dalia M Hassan, Safa F Ali, Noor Mahdi
J. Bio. Env. Sci.16( 3), 12-17, March 2020.
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In recent years, synthesized zinc oxide nanoparticles have been increasingly investigated for different medicinal uses. In the present study, we aimed at the biosynthesis of zinc oxide using a curcumin extract. Although, toxic effects of curcumin derivative and zinc oxide nanoparticles in different concentration have been studied specifically on animal models besides the antibacterial activity of synthesized curcumin extract and zinc oxide nanoparticles. The aim of the study was to synthesize extract combined zinc oxide nanoparticles. Methods: The synthesized nanoparticles and extract were characterized for the particle size distribution, morphology, optical properties and surface charge by using UVvisible spectroscopy, dynamic light scattering (DLS), (TEM) and (SEM). Elemental composition and structural properties were studied by energy dispersive X-ray spectroscopy (EDX) and X-ray diffraction spectroscopy (XRD). Results: The synthesized nanoparticles and curcumin were irregular shape and had a size distribution in the range of 50–100 nm. The in vitro toxicity effects of zinc oxide and extract showed no toxic effect with different concentration with antibacterial effect.


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