Effect of illicit drugs and alcoholism on cardiac enzymes

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Research Paper 01/07/2019
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Effect of illicit drugs and alcoholism on cardiac enzymes

Muhammad Jaseem Khan, Heena Bibi
Int. J. Biosci.15( 1), 542-547, July 2019.
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The use of illicit drugs is spread worldwide. Drugs have serious effect on human health and in many cases deadly. It damage cardiac tissues and release cardiac enzymes due to injury/damage to it. Main objective of the study was to evaluate the effect of illicit drugs on cardiac enzymes and to know the correlation of single drug, double drugs, triple drugs and multiple drugs effect on cardiac enzymes. A study was conducted in the Institute of Paramedical Sciences Khyber Medical University Peshawar. For CK and LDH estimation, 183 male illicit drug users and for CKMB 107 were recruited. Control group were also taken with same age group, number and population. The patient blood samples were tested for LDH, CK and CKMB by Chemistry analyzer AMP. The statistical analysis was carried out using paired t-sample test. After analysis our study revealed that illicit drug abuse has sufficient influence on cardiac enzymes and multiple drugs using reinforced elevation in cardiac enzymes. These findings indicated of myocardial tissue damage with comparison in control groups. Illicit drugs lead to heart muscles damaged and caused release of elevated level of cardiac enzymes.


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