Effect of supplementary consumption vitamin B1 (thiamine) on blood glucose changes during and after maximal aerobic exercise
Paper Details
Effect of supplementary consumption vitamin B1 (thiamine) on blood glucose changes during and after maximal aerobic exercise
Abstract
The purpose of the present study was to determine the effect of vitamin B1 (Thiamine pyrophosphate) (TPP) on blood glucose changes. We observed that when the subjects received 300 mg thiamin /day, there was a lowering of blood glucose level during and after physical activity. Like the other B vitamins, thiamin is used to treat fatigue. High-dose thiamin supplementation may be helpful in preventing fatigue or accelerating recovery from exercise-induced fatigue. In this research 36 non-athlete university students male were selected with average 22.8, 179 and 77.16 for age, height and weight respectively,(12 persons in each group).The subjects placed in three groups: Experimental Group A(EGA),Experimental Group B(EGB) and Control Group(CG).They have to exercise on treadmill before and after the thiamin consumption. First of all, blood glucose measured in three groups before exercise and then performed exercise on treadmill until exhaustion. Blood glucose changes in subjects measured by (GOD-PAP method) after 5 minutes and in the end of the exercise (pre-test).The subject’s consumed thiamin during 10 days (EGA 30 mg /day, EGB 300 mg/day and CG just placebo) Blood glucose changes measured in three groups like as pre-test, during and the end of the exercise on treadmill after 10 days (post-test). Our results indicates, that there is no changes in blood glucose in EGA (30 mg thiamin/day) and CG(placebo) but showed that blood glucose reduced in EGB (300 mg thiamin/day)(P>0.05). In fact, degree of exhaustion increased in EGB that they consumed 300 mg thiamin per day, and they could to do exercise for a long time. Like the other B vitamins, thiamin is used to treat fatigue. High-dose thiamin supplementation may be helpful in preventing fat.igue or accelerating recovery from exercise-induced fatigue.
Akiko S, Yoshimitsu S, Tomoji I, Nobuko M. 2011. Dietary thiamin and riboflavin intake and blood thiamin and riboflavin concentrations in college swimmers undergoing intensive training. International journal of sport nutrition and exercise metabolism 21(3), 195 -204.
Allen DG, Lamb GD, Westerblad H. 2008. Skeletal muscle fatigue: Cellular mechanisms. Physiological Review 88(1), 287–332. http://dx.doi.org/10.1152/physrev.00015.2007
Arici C, Tebaldi A, Quinzan GP, Maggiolo F, Ripamonti D, Suter F. 2001. Severe lactic acidosis and thiamine administration in an HIV-infected patient on HAART. International Journal of STD & AIDS 12(6), 407-409. http://dx.doi.org/10.1258/0956462011923228
Bautista-Hernandez VM. 2008. Effect of Thiamine Pyrophosphate on Levels of Serum Lactate, Maximum Oxygen Consumption and Heart Rate in Athletes Performing Aerobic Activity.” The Journal of international medical research 36(6), 31-38.1220-1226. http://dx.doi.org/10.1177/147323000803600608
Chobitko VG, Zakharova NB. 1993. Prediction of the effects of energy-stabilizing drugs in diabetes mellitus. Klinicheskaia Laboratornaia Diagnostika 0(3), 15-17.
Gladden B. 2001. Lactic acid: New roles in a new millennium. Proceedings of the National Academy of Sciences 98(2), 395-7. http://dx.doi.org/10.1073/pnas.98.2.395
Hatta H, Soma R, Atomi Y. 1991. Effect of dichloroacetate on oxidative removal of lactate in mice after supramaximal exercise. Comparative Biochemistry and Physiology 100(3), 561–564. http://dx.doi.org/10.1016/0305-0491(91)90220-8
Holloszy JO and Coyle EF. 1984. Adaptations of skeletal muscle to endurance exercise and their metabolic consequences. Journal of Applied Physiology 56(4), 831-838.
Kitamori N, Itokawa Y. 1993. Pharmacokinetics of thiamine after oral administration of thiamine tetrahydrofurfuryl disulfide to humans. Journal of Nutritional Science Vitaminology 39(5), 465–472.
Knippel M, Mauri L, Belluschi R. 1986. The action of thiamin on the production of lactic acid in cyclists. Medicine in Sport 39(1), 11-16
Larrieu AJ, Yazdanfar S, Redovan E, Eftychiadis A, Kao R, Silver J. 1987. Beneficial effects of cocarboxylase in the treatment of experimental myocardial infarction in dogs. American Surgeon 53(12), 721-725.
Lonsdale D. 2006. A review of the biochemistry, metabolism and clinical benefits of thiamin (e) and its derivatives. Evidence-Based Complementary and Alternative Medicine 3(1), 49–59. http://dx.doi.org/10.1093/ecam/nek009
MacRae HS, Dennis SC, Bosch AN, Noakes TD. 1992. Effects of training on lactate production and removal during progressive exercise in humans. Journal of Applied Physiology 72(5), 1649-1656.
Marcus R, Coulston AM. 2001. Water-soluble vitamins.The vitamin B complex and ascorbic acid. In:Goodman and Gilman’s the Pharmacological Basis of Therapeutics (Hardman JG, Limbird LE, eds). New York: McGraw-Hill 3, 1753 – 1756.
McNeill AW, Mooney TJ. 1983. Relationship among carbohydrate loading, elevated thiamine intake cardiovascular endurance of conditioned mice. The Journal of sports medicine and physical fitness 23(3), 257-262.
Nelson DL, Cox MM. 2000. Lehninger Principles of Biochemistry. New York: Worth Publishers,
Ozawa H, Homma Y, Arisawa H, Fukuuchi F and Hand a S. 2001. Severe Metabolic acidosis and heart failure due to thiamine deficiency. Nutrition 17(4), 351-3522. http://dx.doi.org/10.1016/S0899-9007(00)00588-8
Paquet RJ, Mehlman MA. 1972. Thiamin deficiency.Effect of fatty acids on glucose synthesis in kidney cortex slices from thiamin-deficient rats. The Journal of Biological Chemistry 247(15), 4905– 4907.
Park DH, Gubbler CJ. 1996. Studies on the physiological functions of thiamine: Effects of thiamine antagonists on blood pyruvate and lactate levels and activity of lactate dehydrogenase and its isozymes in blood and tissues. Biochimica & Biophysica Acta 177(3), 537–543.
Parolin ML, Chesley A, Matsos MP, Spriet LL, Jones NL,Heigenhauser GJF. 1999. Regulation of skeletal muscle glycogen phosphorylase and PDH during maximal intermittent exercise. American Journal of Physiology – Endocrinology and Metabolism 277(5), 890–900.
Romanski S and McMahon M. 1999. Metabolic acidosis and thiamine deficiency. Mayo Clinic Proceedings 74(3), 259-263. http://dx.doi.org/10.4065/74.3.259
Strumilo, Slawomir, Jan Czerniecki, and Pawel Dobrzyn. 1999. Regulatory effect of thiamin pyrophosphate on pig heart pyruvate dehydrogenase complex. Biochemical and biophysical research communications 256(2), 341-345. http://dx.doi.org/10.1006/bbrc.1999.0321
Suzuki, Masashige, Yoshinori Itokawa. 1996 Effects of thiamine supplementation on exercise-induced fatigue. Metabolic brain disease 11(1), 95-106. http://dx.doi.org/10.1007/BF02080935
Tabatabaie H. Goodarzi H. 2003. Effect of supplement B1 on glucose and lactic acid concentration after maximal aerobic exercise. Proceeding of 4th international conference on physical education and sport sciences. IR. Iran
Veech RL, Veloso D, Mehlman MA. 1973. Thiamin deficiency: liver metabolite levels and redox and phosphorylation states in thiamin-deficient rats. The Journal of Nutrition 103(2), 267–272.
Wasserman K, Beaver WL and Whipp BJ. 1986. Mechanisms and patterns of blood lactate increase during exercise in man. Medicine and Science in Sports and Exercise 18(3), 344-52.
Webster MJ, Scheet TP, Doyle MR, Branz M. 1997. The effect of a thiamin derivative on exercise performance. European journal of applied physiology and occupational physiology 75(6), 520-524. http://dx.doi.org/10.1007/s004210050198
Webster MJ. 1998. Physiological and perfomance responses to supplementation with thiamin and pantothenic acid derivatives. European journal of applied physiology and occupational physiology 77(6), 486-491. http://dx.doi.org/10.1007/s004210050364
Woolf, Kathleen, and Melinda M. Manore. 2006. B-vitamins and exercise: does exercise alter requirements? International journal of sport nutrition and exercise metabolism 16(5), 453-484.
Kasbparast JR Mehdi, Keshavarzi Hamid reza, Masoumi Saba, Moghadami Kamilia (2013), Effect of supplementary consumption vitamin B1 (thiamine) on blood glucose changes during and after maximal aerobic exercise; IJB, V3, N7, July, P195-201
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