Welcome to International Network for Natural Sciences | INNSpub

Effects of different levels of copper sulfate on small on intestinal physiology in japanese quail (Coturnix coturnix japonica)

Research Paper | December 1, 2013

| Download 4

Mehdi Zahedi, Jamshid Ghiasi Ghalehkandi, Yahya Ebrahimnezhad

Key Words:

Int. J. Biosci.3( 12), 252-257, December 2013

DOI: http://dx.doi.org/10.12692/ijb/3.12.252-257


IJB 2013 [Generate Certificate]


This study was conducted to evaluate the effects of different Levels of copper sulfate on small intestine morphometry in Japanese quail. Four hundred and twenty, day old male Japanese quail randomly assigned into 5 treatments with 4 replicates (each replicates contain 20 birds). All experimental birds were received basal diet without copper sulfate from day 1 to 7. At day 8, experimental birds were received experimental diets: Control group (A) received basal diet, whereas B, C, D and E groups were received basal diet supplemented by 50, 100, 150 and 200 mg copper sulfate, respectively. At day 42, three birds from each group were randomly selected and slaughtered. Various sections of small intestine (10, 50 and 70 small intestine length) sampled, rinsed with phosphate to measure villi length and depth of liberkuhn crypts. According to the results, a significant increase was observed in depth of liberkuhn crypts (10% intestine length) and villi height (70% intestine length) in birds fed diet contain 200 mg copper sulfate (p<0.05). Furthermore, supplementation of various levels of copper sulfate significantly decreased depth of liberkuhn crypts and villi height in the other portion of small intestine in Japanese quail (p>0.05). It seems, different Levels of copper sulfate were not able to improve small intestine morphometry in Japanese quail.


Copyright © 2013
By Authors and International Network for
Natural Sciences (INNSPUB)
This article is published under the terms of the Creative
Commons Attribution Liscense 4.0

Effects of different levels of copper sulfate on small on intestinal physiology in japanese quail (Coturnix coturnix japonica)

Antheony C, Nguyen J, Griffian A. 1999. In vitro and in vivo evaluation of effects of sodium caprate on enteral peptide absorption and on mucosal morphology. International Pharmacology 191, 15-24.

Arias VJ, Koutsos EA. 2006. Effects of Copper Source and Level on Intestinal Physiology and Growth of Broiler Chickens. Journal of Poultry Science 85, 999-1007.

Barber RS, Braude R, Mitchell KG, Rook JA, Rowell JG. 1957. Further studies on antibiotic and copper supplements for fattening pigs. British Journal of Nutrition 11, 70-79.

Bayer RC, Chawan CB, Bird FH, Musgrave SD. 1975. Characteristics of the absorptive surface of the small intestine of the chicken from 1 day to 14 weeks of age. Journal of Poultry Science 54, 155-169.

Choct M. 1999. Soluble non-starch polysaccharides affect net utilisation of energy by chickens. Recent Advances in Animal Nutrition in Australia 12, 31-35.

Clarke RM. 1977. The effects of age on mucosal morphology and epithelial cell production in rat small intestine. Journal Anat 123, 805-811.

Ghodasara SN, Fefar DT, Kalaria VA, Bhadaniya AR, Savsani HH. 2013. Clinical management of Zinc phosphide toxicity in German Shepherd dog. Research Opinion Animal Veterinary Science 3(10), 335-336.

Gohl B, Gohl I. 1977. The effect of viscous substances on the transit time of barley digesta in rats. Journal of Science Food and Agriculture 28, 911-915.

Hill GM, Cromwell GL, Crenshaw TD, Dove CR, Ewan RC, Knabe DA, Lewis AJ, Libal GW, Mahan DC, Shurson GC, Southern LL, Veum TL. 2000. Growth promotion effects and plasma changes from feeding high dietary concentrations of zinc and copper to weanling pigs (regional study). Journal of Animal Science 78, 1010-1016.

Hill KJ. 1971. The physiology of digestion. In: Physiology and biochemistry of the domestic fowl. (Ed. Bell DJ and Freeman BM). Academic Press, New York. 28-32 p.

Iji PA. 1999. The impact of cereal non-starch polysaccharides on intestinal development and function in broiler chickens. World’s Poultry Science Journal 55(4), 375-387.

Iji PA, Saki A, Tivey DR. 2001. Body and intestinal growth of broiler chicks on a commercial starter diet. 1. Intestinal weight and mucosal development. British Journal of Poultry Science 42, 505-513.

Iqbal R, Malik F, Aziz T, Sarfraz I, Ahmed Z, Shafqat S. 2012. The Study of Histopathological Changes upon Exposure to Vinegerized Copper Sulphate in Liver and Kidney of Broiler Chick. Middle-East Journal of Scientific Research 12 (1), 36-41.

Jenkins NK, Morris TR, Valamotis D. 1970. The effect of diet and copper supplementation on chick growth. British Journal of Poultry Science 11, 241-248.

Jin S, Corless A, Sell JL, Jin SH. 1998. Digestive system development in post-hatch poultry. World’s Poultry Science Journal 54 (4), 335-345.

Miles RD, O’Keefe SF, Henry PR, Ammerman CB, Luo XG. 1998. The effect of dietary supplementation with copper sulfate or tribasic copper chloride on broiler performance, relative copper bioavailability, and dietary prooxidant activity. Journal of Poultry Science 77,416-425.

Mouwen  JMVM.  1971.  White  scours  in  piglets. Veterinary Path 8, 364-80.

Noy Y, Sklan D. 1995. Digestion and absorption in the young chicks. Journal of Poultry Science 74, 366-373.

Pang Y, Applegate TJ. 2007. Effects of Dietary Copper Supplementation and Copper Source on Digesta pH, Calcium, Zinc, and Copper Complex Size in the Gastrointestinal Tract of the Broiler Chicken. Journal of Poultry Science 86(3), 531-7.

Pang Y, Patterson JA, Applegate TJ. 2009. The influence of copper concentration and source on ileal microbiota. Journal of Poultry Science 88, 586-592.

Pesti GM, Bakalli RI. 1996. Studies on the feeding of cupric sulfate pentahydrate and cupric citrate to broiler chickens. Journal of Poultry Science 75, 1086-1091.

Ruttanavut J, Yamauchi K, Goto H, Erikawa T. 2009. Effects of dietary bamboo charcoal powder including vinegar liquid on growth performance and histological intestinal change in aigamo ducks. Intrnational Journal of Poultry Science 8, 229-236.

SAS Inc. 2007. SAS OnlineDoc® 9.1.3. Cary, NC, USA.

Shin BL, Chen YH, Hsu JC. 2013. Morphological development of the small intestine in white Roman goslings. African Journal of Biotechnology 12(6), 611-617.

Smith MS. 1969. Responses of chicks to dietary supplements of copper sulphate. British Poultry Science 10, 97-108.

Uni Z, Ganot S, Sklan D. 1998. Posthatch development of mucosal function in the broiler small intestine. Journal of Poultry Science 77, 75-82.

Uni Z, Noy Y, Sklan D. 1995. Posthatch changes in morphology and function of the small intestines in heavy- and light-strain chicks. . Journal of Poultry Science 74, 1622-1629.

van der Klis, JD, Van Voorst A. 1993. The effect of carboxy methyl cellulose (a soluble polysaccharide) on the rate of marker excretion from the gastrointestinal tract of broilers. Journal of Poultry Science 72, 503-512.

Yamauchi K, Buwjoom T, Koge K, Ebashi T. 2006. Histological intestinal recovery in chickens refed dietary sugar cane extract. Journal of Poultry Science 85, 645-651.

Zhang XH, Zhong X, Zhou YM, Du HM, Wang T. 2009. Effect of RRR-“-tocopherol succinate on the growth and immunity in broilers. Journal of Poultry Science 88, 959- 966.