Epidemics of dengue virus in the recent outbreak in 2017, in District Mardan, Khyber-Pakhtunkhwa province of Pakistan
Paper Details
Epidemics of dengue virus in the recent outbreak in 2017, in District Mardan, Khyber-Pakhtunkhwa province of Pakistan
Abstract
This study aimed to find out the recent burden of dengue virus infection during the recent epidemic in district Mardan in 2017. The suspected patients of Dengue Virus infection from different areas of district Mardan were hospitalized at Mardan Medical Complex (MMC). The admitted patients were treated in an isolated ward specified for Dengue cases. We came across 2421 suspected cases of Dengue fever during 11 months period (January to November, 2017). The suspected individuals have been screened for dengue infection through Immunochromato graphic technique (ICT), having recombinant NS1 antigen and both antibodies IgM and IgG coated. About 313 cases were found positive for dengue IgG, IgM, or both IgG and IgM, NS1, NS1+IgM, NS1+IgG, NS1+IgM+IgG. The dengue infection rate in males (214) was higher as compared to females (99). The rate of infection was found more in the age range of 15-35 years of age (44.08%). All the patients were suffering from severe fever (97.5%), Skin rash (20%), Abdominal pain (40%), Vomiting (50%), Nose bleeding (Epistaxis55%), Gum bleeding (33%), Haematemesis (30%) headache and Fatigue. Although Dengue virus infections has greater epidemic in some of the regions of KPK province in 2017 but in Mardan district least number of individuals have been affected. Our findings show male subjects’ seroprevalence is more as compared to female in the recent outbreak.
Akram DS, Igarashi A, Takasu T. 1998. Dengue virus infection among children with undifferentiated fever in Karachi.Indian J Pediatr 65, 735-740.
Ali A, Nasim Z, Rehman R, Farzana AS, Zahir F, Iqbal A. 2013. Dengue virus serotype 2 and 3 causing high morbidity and mortality in Swat, Pakistan. Biohelikon Immun Dis 1, 1-3.
Ali A, Rehman HU, Nisar M, Rafique S, Ali S. et al. 2013. Seroepidemiology of dengue fever in Khyber Pakhtunkhawa, Pakistan.Int J Infect Dis 17(7), 518-523.
Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, Drake JM, Brownstein JS, Hoen AG, Sankoh O, and Myers MF. 2013. The global distribution and burden of dengue. Nature 496(7446), 504-507.
Butt Q. 2010. Dengue will continue to haunt Pakistan for many years Available from URL: http://tribune.com.pk/story/304451/dengue-will-continue-to-hauntpakistan-for-many-years/.,
Chan YC, Salahuddin NI, Khan J, Tan HC, Seah CL. 1995. Dengue haemorrhagic fever outbreak in Karachi, Pakistan, (1994). Trans R Soc Trop Med Hyg 89, 619-620.
Fatima Z, Idrees M, Bajwa MA, Tahir Z, Ullah O. 2011. Serotype and genotype analysis of dengue virus by sequencing followed by phylogenetic analysis using samples from three mini outbreaks-2007-2009 in Pakistan. BMC Microbiol 11, 200.
Gubler DJ, Trent DW. 1993. Emergence of epidemic dengue/dengue hemorrhagic fever as a public health problem in the Americas. Infect Agents Dis 2, 383-393.
Gubler DJ. 1996. Arboviruses as imported disease agents: The need for increased awareness. Arch virol Suppl 11, 21-32.
Khan E, Hasan R. 2011. Dengue Infection in Asia; A Regional Concern. J Postgrad Med Inst 26, 01-06.
Khan J, Khan A. 2015. Incidence of dengue in 2013. Dengue outbreak in District Swat, Khyber Pakhtunkhwa, Pakistan. Inter J of Fauna and Biolo Stud 2(1), 1-7.
Murray NEA, Quam MB, Wilder-Smith A. 2013. Epidemiology of dengue: past, present and future prospects. Clinical epidemiology 5, 299.
Strobel M, Lamaury I. 2001. Dengue fever: A review. Rev Med Interne 22(7), 638-647.
Sajid Ali, Nourin Mahmood, Jehan Zeb Afridi, Bashir Ahmad, Abdullah, Misbahud Din, Munib Ahmad, Faisal Hayat Khan, Fazal Jalil, 2018. Epidemics of dengue virus in the recent outbreak in 2017, in District Mardan, Khyber-Pakhtunkhwa province of Pakistan. Int. J. Biosci., 12(3), 280-284.
Copyright © 2018 by the Authors. This article is an open access article and distributed under the terms and conditions of the Creative Commons Attribution 4.0 (CC BY 4.0) license.