Ethno-botanical survey of some anticancer medicinal plants from Garhwal Himalaya (Uttarakhand) India
Paper Details
Ethno-botanical survey of some anticancer medicinal plants from Garhwal Himalaya (Uttarakhand) India
Abstract
Ethno-botanical survey of the plants used in the management of cancer was carried out in Garhwal Himalaya, Uttarakhand, India. Herbalists, herb sellers and traditionalists living within the study area were interviewed by the administration of questionnaires. This article considers 20 medicinal plants belong to 16 families, and their different parts (root, stem, bark, bulb, leaf, fruit and seed) or the whole plants/herbs are used. The extracts or decoctions of these are generally used in the anticancer recipes. A need for further scientific research based on the findings of this survey is indeed very necessary and recommended so that adequate records of indigenous methods for the management of cancer can be kept for posterity especially in the study area. A need for analytical work on the plants identified as useful for the management of cancer is also necessary in order to determine the actual dosage applicable so that the medicinal value of these plants could be made available to humanity and hence reduce pain, cost and sudden death of the peoples.
Bhishagratha KL. 1991. Sushruta Samhita. Varanasi: Choukhamba Orientalia.
Brook G, La Thanque NB. 1999. Drug discovery and the cell cycle, The promise and the Hope, Drug Discovery Today 4, 455-464.
Cragg GM, Newman DJ. 2005. Plants as source of anticancer agents, Journal of Ethnopharmacology 100 (1-2), 72-79.
Devmurari VP, Jivani NP. 2010. Anticancer Evaluation of Artemisia nilagirica, International Journal of Pharm. Tech Research 2(2), 1603-1608.
Diwanay S, Chitre D, Patwardhan B, 2004. Immunoprotection by botanical drugs in cancer chemotherapy, Journal of Ethno-pharmacology 90(1), 49-55.
Dung NX, Ngoc PH, Rang DD, Nhan NT, Klinkb N, Leclercq P. 2001. Chemical composition of the volatile concentrate from the flowers of Vietnamese Alstonia scholaris (L.) R.Br. Apocynaceae. Journal Essential Oil Research, 13 (6), 424-426.
Duvoix A, Blasius R, Delhalle S, Schnekenburger M, Morceau F, Henry E, Dicato M, Diederich M. 2005. Chemopreventive and therapeutic effects of curcumin. Laboratoire de Biologie Moleculaire et Cellulaire du Cancer. Cancer Lett. 223(2), 81-190.
Foster S, Duke JA. 1990. A Field Guide to Medicinal Plants. New York: Houghton Mifflin. 46.
Gaur RD. 1999. Flora of the District Garhwal: North West Himalaya (with ethnobotanical notes) Transmedia, Srinagar Garhwal.
Ghamande S, Lele S, Marchetti D, Baker T, Odunsi K. 2003. Weekly paclitaxel: in patients with recurrent or persistent advanced ovarian cancer. Int. J Gynecol Cancer, 13, 142-147.
Hsu YL, Cho CY, Kuo PL, Huang YT, Lin CC. 2006. Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo. JPET 318, 484-494.
Huang Y, Fang Y, Wu J, Dziadyk JM, Zhu X, Sui M and Fan W. 2004. Regulation of Vinca alkaloid-induced apoptosis by NF-kB/IkB pathway in human tumor cells. Mol Cancer Ther, 3, 271-277.
Jain SK, Rao RR. 1977. Field and Herbarium Methods. Today and Tomorrow Printers and Publishers, New Delhi.
Jang M, Cai L, Udeani GO, Beecher CWW, Fong HHS, Farnsworth NR. 1997. Cancer chemopreventive activity of Resveratrol, a natural product derived from Grapes. Science 275, 218–20.
Kinjavadekara RS. Astanga sangraha. New Delhi: Uppal Publishing House. 1998.
Koduru S, Grierson DS & Afolayan AJ, 2007. Ethno-botanical information of medicinal plants used for treatment of cancer in the Eastern Cape Province, South Africa. Current Science 92 (7), 906-908.
Kuo PL, Hsu YL, Lin TC, Lin LT, Chang JK, Lin CC. 2005. Casuarinin from the bark of Terminalia arjuna induces apoptosis and cell cycle arrest in human breast adenocarcinoma MCF-7 cells. Planta Med. 71(3), 237-43.
Kumar RA, Sridevi K, Kumar NV, Nanduri S and Rajagopal S. 2004. Anticancer and immunostimulatory compounds from Andrographis paniculata. J. Eth. Pharmacol. 92(2-3), 291-295.
Kumaran KS, Thirugnanasambantham P, Viswanathan S, Ramamurthy MS. 2003. An HPLC method for the estimation of andrographolide in rabbit serum, Ind J Pharmacol, 35(2), 109-112.
Lissoni P, Giani L, Zerbini S, Trabattoni P, Rovelli F. 1998. Biotherapy with the pineal immunomodulating hormone melatonin versus melatonin plus Aloe vera in Untreatable advanced solid neoplasm, Nat Immun. 16, 27-33.
Liu W, Kato M, Akhand A. 1998. The herbal medicine Sho-saiko-to inhibits the growth of malignant melanoma cells by up-regulating Fasmediated apoptosis and arresting cell cycle through down regulation of cyclin dependent kinases, International Journal of Oncology 12, 1321-1326.
Luck HJ, Roche H. 2002. Weekly paclitaxel: an effective and well-tolerated treatment in patients with advanced breast cancer. Crit Rev Oncol Hematol. 44, 15–30.
Madhuri S & Pandey G. 2009. Some anticancer medicinal plants of foreign origin, Current Science 96(6), 779-783.
Mouli KC, Vijaya T, Rao SD. 2009. Phytoresources as potential therapeutic agents for cancer treatment and prevention, Journal of Global Pharma Technology 1(1), 4-18.
Pandey G, Madhuri S. 2010. Some medicinal plants as natural anticancer agents. Phcog, Rev 3(6), 259-263.
Rang HP, Dale MM, Ritter JM. 2001. Pharmacology, 4th edition Churchill living stone, London, 830.
Sengupta A, Ghosh S, and Bhattacharjee S. 2004. Allium vegetables in cancer prevention: an overview. Asian Pac. J Cancer. Prev. 5(3), 237-245.
Singh HB, Subramaniyam. 2008. Field manual of Herbarium Techniques NISCAIR (CSIR), New Delhi.
Sunwoo JB, Herscher LL, Kroog GS. 2001 Concurrent paclitaxel and radiation in the treatment of locally advanced head and neck cancer. J Clin Oncol. 19, 800-11.
Tripathi YB, Sharma M and Manickam M. Rubiadin. 1997. A new antioxidant from Rubia cordifolia. Ind. J. Biochem. Biophys. 34(3), 302-306.
WHO. 1998. Regulatory situation of herbal medicines. A worldwide review, Geneva Switzerland, 1–5.
Antima Sharma, L.R Dangwal, Upvan Bhushan, Pratima Bhushan, C.S Rana (2012), Ethno-botanical survey of some anticancer medicinal plants from Garhwal Himalaya (Uttarakhand) India; JBES, V2, N12, December, P1-7
https://innspub.net/ethno-botanical-survey-of-some-anticancer-medicinal-plants-from-garhwal-himalaya-uttarakhand-india/
Copyright © 2012
By Authors and International
Network for Natural Sciences
(INNSPUB) https://innspub.net
This article is published under the terms of the
Creative Commons Attribution License 4.0