Ethnobotanical study of Acalypha wilkesiana (Euphorbiaceae), a plant used in the treatment of arterial hypertension in Oyem in Northern Gabon

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Research Paper 10/04/2022
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Ethnobotanical study of Acalypha wilkesiana (Euphorbiaceae), a plant used in the treatment of arterial hypertension in Oyem in Northern Gabon

Wensleslace Landry Mve Mendame, Boris Achille Eyi Mintsa, Alban-Michel Nguema Nguema, Arnaud Brice Pambo Pambo. ET Ibrahim
Int. J. Biomol. & Biomed.14( 2), 1-6, April 2022.
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Cardiovascular diseases, in particular arterial hypertension, are one of the causes of mortality and morbidity in the world, the impact of the treatment is very important, for this the poor populations have difficulties and turn to traditional therapists for treat these pathologies using plants. Thus, our investigations on the use of plants, in the form of an ethnobotanical survey, were carried out in the town of Oyem with 50 people questioned, composed of men (84%) and women (16%) with an age varying between 43 and 75 years. At the end of this investigation, 10 plants were inventoried but Acalypha wilkesiana which is the main object because of its high frequency of use will be studied in particular. The species A. wilkesiana is used to treat several conditions, particularly hypertension. Regarding the organs, the leaves are the most used parts of the plant (93%). The treatment is administered in the form of a decoction (54%) and maceration (40%). These results constitute a database for carrying out phytochemical and biological tests in the search for new bioactive antihypertensive molecules in plants.


Adomou AC, Yedomonhan H, Djossa B, Legba SI, Oumorou M, Akoegninou A. 2012. Étude Ethnobotanique des plantes médicinales vendues dans le marché d’Abomey Calavi au Bénin. International Journal of Biology and Chemestry Science 6, 745-772.

Aladejimokun AO, Daramola KM, Osabiya OJ, Arije OC. 2017. Comparative Study of Phytochemical Constituents and Antimicrobial Activities of Acalypha wilkesiana and Acalypha godseffiana Extracts. Journal of Advanced Microbiology 4, 2456-7116.

Béné K, Camara D, Fofie NBY, Kanga Y, Yapi AB, Yapo YC, Ambe SA, Zirihi GN. 2016. Étude ethnobotanique des plantes médicinales utilisées dans le Département de Transua, District du Zanzan (Côte d’Ivoire). Journal of Animal & Plant Sciences 27, 4230-4250.

Bruneton J. 1999. Pharmacognosie, Phytochimie, Plantes Médicinales. Editions TEC & DOC: Paris 783-785.

Chanet A, Milenkovic D, Manach C, Mazur A, Morand C. 2012. Citrus flavanones: what is their role in cardiovascular protection? Journal of Agricol Food Chemistry 60, 8809-8822.

Del Rio D, Rodriguez-Mateos A, Spencer JP, Tognolini M, Borges G, Crozier A. 2013. Dietary (poly) phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxid Redox Signal 18, 1818-1892.

Dibong SD, Mpondo-Mpondo E, Ngoye A, Kwin MF, Betti JL. 2011. Ethnobotany and phytomedicine of medicinal plants sold in Douala markets. Journal of Applied Biosciences 37, 2496-2507.

Gonzales MM, Tarumi T, Tanaka H, Sugawara J, Swann-Sternberg T, Goudarzi K, Haley AP. 2010. Functional imaging of working memory and peripheral endothelial function in middle-aged adults. Brain and Cognition 73, 146-151.

Houehanou C, Amidou S, Preux PM, Houinato D, Lacroix P. 2018. Hypertension artérielle (HTA) en Afrique subsaharienne. Journal de Médecine vasculaire 43, 87.

Ibrahim B, Attéké NC, Moungengui S, Lépengué NA, Issembé AY, Nsi Akoué G, Souza A, M’batchi B. 2015. Medicinal and aromatic plants 5.

Morand C, Milenkovic D. 2014. Polyphénols et santé vasculaire : mise en évidence du rôle direct des polyphénols dans les effets bénéfiques des agrumes dans la protection vasculaire. Innovations Agronomiques 42, 47-62.

Mpondo EM, Didier SD, Richard JP, Alfred N, Christelle FLY. 2012. Etude actuelle de la médecine traditionnelle dans le système de santé des populations rurales et urbaines de Douala (Cameroun). Journal of Applied Biosciences 55, 4036- 4045.

N’Guessan K, Beugré K, Guédé NZ, Dossahoua T, Laurent A. 2009. Screening phytochimique de quelques plantes médicinales ivoiriennes utilisées en pays Krobou (Agboville, Côte-d’Ivoire). Sciences & Nature 6, 1-15.

Nsi Akoué G. 2017. Etude des plantes médicinales et/ou alimentaires issues du régime alimentaire du mandrill (Mandrillus sphinx) : approche zoopharmacognosie. Thèse de doctorat, Université de Sciences et Techniques de Masuku, Gabon 105-110.

Nworgu ZAM, Ameachina FC, Owolabi J, Otokiti I, Ogudu U. 2011. Cardiovascular Effects of Aqueous Extract of Acalypha Wilkesiana Hoffmannii Leaves In Rabbits And Rats. Nigerian Journal of Pharmacology Science 10, 45-50.

Odoh UE, Ndubuokwu RI, Inya-Agha SI, Osadebe PO, Uzor PF, Ezejiofor M. 2014. Antidiabetic activity and phytochemical screening of Acalypha wilkesiana (Euphorbiaceae) Mull Arg. roots in alloxan-induced diabetic rats. Science Research Essays 9, 204-212.

Organisation Mondiale de la Santé. 2011. Gouvernance santé et population. Stratégie OMS de coopération avec les pays en développement p. 5.

Ouattara D. 2006. Contribution à l’inventaire des plantes médicinales significatives utilisées dans la région de Divo (sud forestier de la Côte d’Ivoire) et à la diagnose du poivrier de Guinée : Xylopia aethiopica (Dunal) A. Rich. (Annonaceae). Thèse de doctorat, Université de Cocody Abidjan, Côte d’Ivoire 184.

Sereme A, Millogo-Rasolodimby J, Guinko S, Nacro M. 2008. Propriétés thérapeutiques des plantes a tanins du Burkina Faso. Pharmacopée et Médecine Traditionnelle Africaines 15, 41-44.

Ueli Z, Lic P, Bopp M. 2008. Chiffres et données sur les maladies cardiovasculaires en Suisse. Fondation Suisse de Cardiologie 1-47.