Evaluating the effect of functional foods supplementation to mitigate hyperglycemia

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Research Paper 01/09/2020
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Evaluating the effect of functional foods supplementation to mitigate hyperglycemia

Mishal Riaz, Tabussam Tufail, Huma Bader Ul Ain, Tara Khursheed, Maria Amjad, Rana Zamin Abbas, Tanazzam Tufail, Muhammad Imran, Ali Saqib, Shahid Bashir, Muhammad Zia Shahid
Int. J. Biosci. 17(3), 164-172, September 2020.
Copyright Statement: Copyright 2020; The Author(s).
License: CC BY-NC 4.0

Abstract

Functional and nutraceutical foods have emerged as a dietary intervention against various lifestyle-related disorders. Their nutritional aspects are primarily in several areas as cancer, cardiovascular disease (CVD), the aging process, diabetes and mental health. This research was conducted to analyze the effect of these oilseeds crops against different diseases and their compositional analysis was performed. To check their effect on human health study was conducted on rats in which effect on serum glucose, serum insulin, lipid profile including LDL, HDL, triglycerides, etc was determined. The effect of sesame on blood profile was studied by adding its specific proportion to rat feed and clinical tests were performed. Results declared that the clinical data consisting of 30 days study indicated that Seesame were found to be effective against diabtes. It was observed that cholesterol level, LDL, HDL were affected positively. Similarly, serum glucose and insulin indicated beneficial behavior in clinical tests. Conclusively, sesame and flaxseed powder because of their miracle properties were found best against cardiovascular diseases, obesity and many other diseases. T2 (25% sesame and 75% flaxseed powder) indicated the best results against hyperglycemia.

Tewfik S, Tewfik I. 2008. Nutraceuticals, functional foods and botanical dietary supplements; promote wellbeing and underpin public health. World review science technology 5, 104-123.

Shahidi F, Naczk B. 2004. Phenolics in food and nutraceuticals. CRC Press, Boca Raton, FL.

Shen H, Price RL, Femandez MI. 2009. Dietary soluble fibers lower plasma LDL cholesterol concentrations by altering lipoprotein metabolism in female guinea pigs. Journal of Nutrition 128, 1434-1441.

Riaz M, Asghar A, Tufail T, Sikander S, Imran M, Ahmed H, Ahsan F, Bashir B, Shahid MZ, Bukht H. 2020. Exploring the prophylactic potential of sesame seed and flaxseed as a functional food. International Journal of Biosciences 17(1), 63-68.

Tufail T, Saeed F, Imran M, Arshad MU, Anjum FM, Afzaal M, Bader Ul Ain H, Shahbaz M, Gondal TA, Hussain S. 2018. Biochemical characterization of wheat straw cell wall with special reference to bioactive profile. International journal of food properties 21(1), p 1303-1310.

Kato MJ, Chu A, Davin LB, Lewis NG. 2005. Biosynthesis of antioxidant lignans in Sesamum indicum L seeds. Phytochemistry 47, 583-591.

Tufail T, Saeed F, Arshad MU, Afzaal M, Rasheed R, Bader Ul Ain H, Imran M, Abrar M, Farooq MA. Shahid MZ. 2020. Exploring the effect of cereal bran cell wall on rheological properties of wheat flour. Journal of Food Processing and Preservation 44(3), p e14345.

Asghar A, Majeed MN, Akhtar MN. 2014. A review on the utilization of sesame as functional food. American Journal of Nutrition 4, 21-34.

Elleuch M, Besbes S, Roiseux O, Blecker C, Attia H. 2007. Quality characteristics of sesame seeds and by products. Food Chemistry 103, 641-650.

Wolf B, Weisbrode S. 2003. Safety evaluation of an extract from Salacia oblonga. Food Chemical Toxicology 41, 867-874.

Kim JY, Paik JK, Kim OY, Park HW, Lee JH, Jang Y, Lee JH. 2011. Effects of lycopene supplementation on oxidative stress and markers of endothelial function in healthy men. Atherosclerosis. 215, 189-195.

Montgomery. 2008. Design and analysis of experiments. 9th Ed. John Wiley and Sons. Inc. Hoboken New Jersey, United States 328-380.

Ford JD, Huang KS, Wang HB, Davin LB, Lewis NG. 2001. Biosynthetic pathway to the cancer chemopreventive secoisolariciresinol diglucoside-hydroxymethl glutaryl esterlinked lignan oligomers in flax (Linum usitatissimum) seed. Journal of Natural Products 64, 1388-1397.

Butt MS, Anjum FM, Bajwa BE, Kausar T, Mukhtar MT. 2007. Effect of flax addition on the flavor profile of muffins and snacks bars Journal of Natural Products 86, 519-601.

Juan X, Chen S, Qiuhui H. 2005. Antioxidant activity of brown pigment and extracts from black sesame seed (Sesamum indicum L.). Food Chemistry. 91, 70-83.

Visavadiya NP, Soni B, Dalwadi N. 2009. Free radical scavenging and antiatherogenic activities of Sesamum indicum L seed extracts in chemical and biological model systems. Food and Chemical Toxicology 47, 2507-2515.

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