Evaluation of anti-inflammatory and analgesic activity from Vitex negundo Linn

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Research Paper 01/01/2014
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Evaluation of anti-inflammatory and analgesic activity from Vitex negundo Linn

Shambaleed humayun, Muhammad Ibrar
J. Bio. Env. Sci.4( 1), 164-172, January 2014.
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Analgesic and anti-inflammatory activity along with phytochemical screening was carried out on leaf ethanolic extract of Vitex negundo Linn. Phytochemical screening has shown presence of various phytochemicals like carbohydrates, proteins, triterpenoids, calcium oxalate, volatile oils, starch, saponin, flavonoides and tannins. Analgesic activity was carried out by using two models (acetic acid model and tail immersion model). Acetic acid model showed significant effects whereas tail immersion model showed non-significant results which mean that the analgesic effects of Vitex negundo is “orally controlled”. Anti-inflammatory activity shows significant results. On the basis of present study it can be suggested that this plant has great potentials as a good and cheap source for anti-inflammatory and analgesic drugs preparations. Further investigation is required to evaluate the therapeutic properties of the plant.


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