Evaluation of Equisetum hyemale and Euphorbia hirta leaf extracts in increasing platelet count of sprague dawley rats
Paper Details
Evaluation of Equisetum hyemale and Euphorbia hirta leaf extracts in increasing platelet count of sprague dawley rats
Abstract
Insufficient platelet production emerged as a global problem and result in a wide variety of health problems. This study aimed to evaluate an alternative to combat low platelet count. The efficacy of Equisetum hyemale and Euphorbia hirta in increasing the platelet count was assessed using experimental pre-test and post-test design consisting of five treatments. Aspirin-induced thrombocytopenia was the model used in Sprague Dawley rats to determine the extracts’ effect in the platelet count within 11 days. On the 4th day to 11th day, the plant extracts showed a significant difference with the negative control. Further, in combination or alone, both plant extracts have no difference compared to the positive control. Hence, the results show that the plant extracts possess platelet-increasing property. The study recommends examining hematology and histopathology of various organs for any side effects.
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