Evaluation of the antibacterial potential of Eruca sativa Mill. (Brassicaceae) in vitro

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Research Paper 01/07/2018
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Evaluation of the antibacterial potential of Eruca sativa Mill. (Brassicaceae) in vitro

Abd Ullah, Javaria Noor, Fawad Ahmad
J. Bio. Env. Sci.13( 1), 44-51, July 2018.
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The alarming increase in antibiotic resistance is a threat to primary healthcare worldwide. Thus, it is very important to investigate the antimicrobial properties of medicinally important plants for the discovery of natural, non-antibiotic based alternative therapies. Leaves and stem crude extracts (chloroform, ethyl acetate and aqueous) of E. sativa Mill. Were screened at four concentrations (0.5, 1.0, 1.5, 2.0 mg/ml) against four pathogenic bacterial strains using standard well diffusion method. Results reveal that E. sativaethyl acetate stem extract (2mg/ml) had shown maximum inhibition against Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus subtilis with 20.47mm, 16.44mmand 15.24mm zone of inhibition respectively whereas; against Klebsiella pneumoniae both ethyl acetate stem extract and chloroform leaves extract had shown maximum inhibition with 19.24 and 18.24mm zone of inhibition respectively. Considerable inhibition had been shown by E. sativa chloroform and aqueous stem extract at a high concentration of 2mg/ml against pathogenic bacterial strains. The overall inhibition was concentration dependent and showing a progressive decrease in inhibition with a decrease in concentration from 2mg/ml to 0.5mg/ml. The present work determined the medicinal and antibacterial importance of E. sativa.


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