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Exercise-induced weigh loss in the absence of a control diet does not affect serum resistin or insulin resistance in obese males

Eizadi Mojtaba, Ahmadi Pezhman, Nasiri Farsani Mokhtar, Torabi Mohsen

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Int. J. Biosci.1(2), 58-66, April 2011


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To investigate effect a merely long time aerobic exercise program in the absence of a control diet on serum resistin and insulin resistance in obese males. A total thirty obese males aged 35 +/- 6 yr were randomly allocated into exercise and control groups. Serum resistin, insulin and glucose were measured after overnight fast before and after a supervised aerobic exercise for 3 month (3 sessions weekly) in exercise group or detraining in control group. Anthropometric assessments also were done in these conditions. Insulin resistance (HOMA-IR) was calculated using fasting insulin and glucose. Statistical analysis was performed using an independent paired t-test. A p-value < 0.05 was considered to be statistically significant. Despite all anthropometrical indexes and body weight were significantly decreased by aerobic exercise program training in exercise group (p<0.05), but serum resistin and insulin resistance remained without change (p≥0.05). All variables remained without change in control group (p≥ 0.05). Based on this data, it was concluded that exercise program in the absence of a control diet does not affect circulation resistin or insulin resistance in obese subjects.


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Exercise-induced weigh loss in the absence of a control diet does not affect serum resistin or insulin resistance in obese males

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