Flavonoid & steroid composition of twelve selected Malaueg medicinal plants

Paper Details

Research Paper 15/07/2022
Views (612) Download (71)
current_issue_feature_image
publication_file

Flavonoid & steroid composition of twelve selected Malaueg medicinal plants

Blancas Pamela Joy S., Diesta Jocelyn S.2, Ramirez Ramelo Jr. B.
J. Bio. Env. Sci.21( 1), 31-36, July 2022.
Certificate: JBES 2022 [Generate Certificate]

Abstract

The search for alternative sources of medicines includes a test for the phytochemical composition. This study aimed to determine the qualitative and quantitative flavonoid and steroid composition of twelve selected Malaueg medicinal plants generally. Specifically, it aimed to determine the leaves of the medicinal plants if it contains the composition of flavonoids and steroids. The presence of flavonoids may indicate its protective effects against many infectious (bacterial and viral diseases) and degenerative diseases such as cardiovascular diseases, cancers, and other age-related diseases. Its presence indicates antioxidative, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties, free radical scavenging capacity, hepatoprotective, capacity to modulate key cellular enzyme functions, and possible inhibition of several enzymes, such as xanthine oxidase (XO), cyclo-oxygenase (COX), lipoxygenase and phosphoinositide 3-kinase. The presence of steroids points to the following potentials of plant steroids: medicinal, pharmaceutical and agrochemical activities like anti-tumor, immunosuppressive, hepatoprotective, antibacterial, plant growth hormone regulator, sex hormone, anti-helminthic, cytotoxic and cardiotonic activity. This study highlights the amount and presence of flavonoids and steroids of 12 medicinal plants. It is recommended that the aqueous extract be studied for the flavonoid presence. It is further recommended that other solvents be utilized in the extraction process.

VIEWS 108

Aska AS, Kubmarawa D, Nkafamiya IA, Shagal HM, Oladosu PO. 2020. Quantitative phytochemical analysis and Anti-tuberculosis activity of some selected medicinal plants in some Northern parts of Bauchi state, Nigeria. Medicine Net. Plant Sterols Supplement: Benefits, Uses, Side Effects, Dosage & Interactions. Retrieved July 16.

Du F, Zhang F, Chen F, Wang A, Wang Q, Yin X, Wang S. 2011. Advances in microbial heterologous production of flavonoids. African Journal of Microbiology Research 5(18), 2566-2574.

Edeoga HO, Okwu DE, Mbaebie BO. 2005. Phytochemical constituents of some Nigerian medicinal plants. African Journal of Biotechnology 4(7), 685-688.

Hemalatha S, Bhaskar Reddy K, Parepalli. 2017. Invitro Antipsoriatic and Inhibitory Effects Of Ethyl Acetate And Methanol Fraction Of Cassia Sophera and Mallotus Philippinensis On Inflammatory Cytokines. International Journal of Phytopharmacology.

Hossain MA, AL-Raqmi KAS, AL-Mijizy ZH, Weli AM, Al-Riyami Q. 2013. Study of total phenol, flavonoids contents and phytochemical screening of various leaves crude extracts of locally grown Thymus vulgaris. Asian Pacific Journal of Tropical Biomedicine 3(9), 705-710. https://doi.org/ 10.1016/s2221-1691(13)60142-2

Iqbal E, Salim KA, Lim LBL. 2015. Phytochemical screening, total phenolics and antioxidant activities of bark and leaf extracts of Goniothalamus velutinus (Airy Shaw) from Brunei Darussalam. Journal of King Saud University – Science 27(3), 224-232.

Kumar S, Pandey AK. 2013. Chemistry and Biological Activities of Flavonoids: An Overview. The Scientific World Journal 1-16  https://doi.org/10.1155 /2013/162750

Kumar U, Kumar B, Bhandari A, Kumar Y. 2010. Phytochemical investigation and comparison of antimicrobial screening of clove and cardamom. Int J Pharm Sci Res 1(12), 138-47.

Mangesh S Kharate, Narayan B Pandhure. 2017. Quantitative Estimation of Phytochemicaland Antimicrobial Properties of Crude Leaf Extract, Mimusopselengi L. International Journal for Research in Applied Science & Engineering Technology (IJRASET) ISSN: 2321-9653; IC Value: 45.98; SJ Impact Factor :6.887 Volume 5 Issue XII December

Marinova D, Ribarova F, Atanassova M. 2005. Total phenolics and total flavonoids in Bulgarian fruits and vegetables. Journal of the university of chemical technology and metallurgy 40(3), 255-260.

Onuh J, Idoko G, Yusufu P, Onuh F. 2017. Comparative Studies of the Phytochemical, Antioxidant and Antimicrobial Properties of Cashew Leaf, Bark and Fruits Extracts. American Journal of Food and Nutrition 5(4), 115-120. https://doi.org/ 10.12691/ajfn-5-4-1

Patel SS, Savjani JK. 2015. Systematic review of plant steroids as potential antiinflammatory agents: Current status and future perspectives. The Journal of Phytopharmacology 4(2), 121-125.

Pratim Sarma M. 2017. Phytochemical Analysis of Traditional Medicinal Plants and their Antimicrobial Activity: An Experience from North East India. Open Access Journal of Pharmaceutical Research 1(1). https://doi.org/10.23880/oajpr-16000104

Robertson Sally. 2018. What are Flavonoids?. News-Medical. Retrieved on July 16, 2020 from https://www.news-medical.net/health/What-are-Flavonoids.aspx.

Roghini R, Vijayalakshmi K. 2018. Phytochemical screening, quantitative analysis of flavonoids and minerals in ethanolic extract of citrus paradisi. International journal of pharmaceutical sciences and research 9(11), 4859-4864.

Saikaew K, Lertrat K, Ketthaisong D, Meenune M, Tangwongchai R. 2018. Influence of variety and maturity on bioactive compounds and antioxidant activity of purple waxy corn (Zea mays L. var. ceratina). International Food Research Journal 25(5), 1985-1995.

Shah MD, Hossain MA. 2014. Total flavonoids content and biochemical screening of the leaves of tropical endemic medicinal plant Merremia borneensis. Arabian Journal of Chemistry, 7(6), 1034-1038. https://doi.org/10.1016/j.arabjc. 2010.12.

Stankovic S, Zia-Ul-Haq M, Bojovic BM, Topuzovic MD. 2014. Agricultural Academy, total Phenolics, flavonoid content and antioxidant power of leaf, flower and fruits from cornelian cherry (Cornus mas L. M.) Bulgarian Journal of Agricultural Science 20 (No 2), 358-363.

Sultan A, Raza AR. 2015. Steroids: A diverse class of secondary metabolites. Med chem 5(7), 310-317.

Sultan A. 2015. Steroids: A Diverse Class of Secondary Metabolites. Medicinal Chemistry 5(7). https://doi.org/10.4172/2161-0444.1000279

Suryawanshi S. 2019. Chemistry and Health benefits to humans of Some Flavonoids: An Overview. Current Pharma Research 9(2), 2799-2804.

Teresa M, Bandiola B. 2018. Extraction and qualitative phytochemical screening of medicinal plants: A brief summary. International Journal of Pharmacy 8(1), 137-143.

Thao NP, Luyen BTT, Kim EJ, Kang JI, Kang HK, Cuong NX, Nam NH, Kiem PV, Minh CV, Kim YH. 2015. Steroidal Constituents from the Edible Sea Urchin Diadema savignyi Michelin Induce Apoptosis in Human Cancer Cells. Journal of Medicinal Food 18(1), 45-53. https://doi.org/ 10.1089/jmf.2013.3105

VK D, VC, SS K. 2020. Phytochemical Studies and In Vitro Evaluation of Antioxidant & Antihyperglycemic Activities of Actinidia deliciosa (A. Chev.) C.F. Liang & A.R. Ferguson (Kiwifruit). Journal of Biochemistry and Analytical Studies 4(1). https://doi.org/10.16966/2576.