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Genome editing a robust way of modifications, a brief introduction of its tools

Review Paper | August 1, 2019

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Shamsa Kanwal, Iram Naurin, Humera Razzaq, Shakra Jamil, Zaffar Iqbal

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Int. J. Biosci.15( 2), 20-32, August 2019

DOI: http://dx.doi.org/10.12692/ijb/15.2.20-32


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Biotechnology is an emerging field. Different biotech tools are used for making improvements in organism’s genetic makeup. This modifying or repairing process of genetic makeup is called genome editing. Different tools are used in this editing system for making desired changes in the genetic makeup. These tools included ZFNs, TALENs and CRISPER. As biotech is robust way of modifications so these advance tools are more helpful than conventional means or tools in field of crop sciences. ZFNs and TALENs have same working principle and cause sit specific breakage and repairing. CRISPER is also used for site directed mutagensis or improvements with more advancements. Locus is found in E. coli. These all tools are widely used and has many applications in crop sciences as well as including successful stories to meet the demand or requirements of population.


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Genome editing a robust way of modifications, a brief introduction of its tools

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