Haemagglutination and Antibacterial activities of Strobilanthes urticifolia Wall. ex Kuntze
Paper Details
Haemagglutination and Antibacterial activities of Strobilanthes urticifolia Wall. ex Kuntze
Abstract
According to literature review there is little or no such reference is available on proposed study. Moreover, the indigenous knowledge on medicinal properties of this plant is not documented so in the current studies, antibacterial activity of crude methanolic extract and its fractions of Strobilanthes urticifolia Wall. ex Kuntze was assessed against seven pathogenic bacterial strains using agar well diffusion method and minimum inhibitory concentration (MIC) was noticed after recording the zone of inhibitions. Crude methanolic extract and its fractions were also investigated for haemagglutination activity. Moderate, weak and no haemagglutination activity was observed against human red blood cells (RBCs) of blood groups by crude methanolic extract and fractions at various dilutions. Of the seven strains studied the widest zone of inhibition (75%) was showed by n-hexane fraction against B. cereus while crude methanolic extract, CHCl3, EtOAc and aqueous fractions were also noticed as equally active against all pathogens. The result got from the study of antibacterial activity clearly suggest that the crude methanolic extract and its fractions of S. urticifolia Wall. ex Kuntze possess potent antibacterial activity and consequently can leads to antibiotics production.
Abo KA, Ogunleye VO, Ashidi JS. 1991. Antimicrobial poteintial of Spondias mombin, Croton zambesicus and Zygotritonia crocea. Journal of Pharmacological Research 5(13), 494-497.
Ahmad B, Azam S, Bashir S, Khan I, Ali N, Chaudhary MI. 2011.Phytotoxic, Antibacterial and Haemagglutination activities of the aerial parts of Myrsine africana L. African Journal of Biotechnology 10(1), 97-102.
Banso A. 2009. Phytochemical and antibacterial investigation of bark extracts of Acacia nilotica. Journal of Medicinal Plants Research 3(2), 82-85.
Duraipandiyan V, Ayyanar M, Ignacimuthu S. 2006. Antimicrobial activity of some ethnomedicinal plants used by Paliyar tribe from Tamil Nadu, India. BMC Complementary Alternative Medicine. 6, 35-41 https://doi.org/10.1186/1472-6882-635
Doughari JH, Human IS, Bennade S, Ndakidemi PA. 2009. Phytochemicals as chemotherapeutic agents and antioxidants: Possible solution to the control of antibiotic resistant verocytotoxin producing bacteria. Journal of Medicinal Plants Research 3(11), 839-848
Doughari JH, Obidah JS. 2008. Antibacterial potentials of stem bark extracts of Leptadenia lancifoli. against some pathogenic bacteria. Pharmacologyonline 3, 172-180.
Fauci AS, Touchette NA, Folkers GK. 2005. Emerging infectious diseases: a 10-year perspective from the National Institute of allergy and infectious diseases. Emerging Infectious Diseases 11(4), 519–525. https://dx.doi.org/10.3201/eid1104.041167
Ghasemzadeh A, Jaafar H, Rahmat A. 2011. Effects of solvent type on phenolics and flavonoids content and antioxidant activities in two varieties of young ginger (Zingiber officinale Roscoe) extracts. Journal of Medicinal Plants Research 5(7), 1147–54
Liu RH. 2004. Potential synergy of phytochemicals in cancer prevention: mechanism of Action. Journal of Nutrition 134(12 Suppl), 3479S-3485S.
Lindequist U, Niedermeyer T, Julich WD. 2005. The pharmacological potential of mushrooms. Evidence-Based Complementary and Alternative Medicine 2, 285–99. http://dx.doi.org/10.1093/ecam/neh107
Mohammedi Z, Atik F. 2011.Impact of solvent extraction type on total polyphenols content and biological activity from Tamarix aphylla L. Karst. International Journal of Pharma and Bio Sciences 2(1), 609–15.
Mukherjee PK. 2002. Quality control of herbal drugs, an approach to evaluation of botanicals. Business Horizons, New Delhi, India 256 P.
Mody R, Joshi SH, Chaney W. 1995. Use of lectins as diagnostic and therapeutic tools for cancer. Journal of Pharmacological and Toxicological Methods 33(1), 1-10. https://doi.org/10.1016/1056-8719(94)00052-6
Mukherjee PK, Wahile. 2006. Integrated approaches towards drug development from Ayurveda and other Indian system of medicines. Journal of Ethnopharmacology103 (1), 25-35 https://doi.org/10.1016/j.jep.2005.09.024
Nweze EL, Okafor JL, Njoku O. 2004. Antimicrobial Activityies of Methanolic extracts of Trume guineesis (Scchumn and Thorn) and Morinda lucinda used in Nigerian Herbal Medicinal practice. Journal of Biological Research and Biotechnology 2(1), 34-46. http://dx.doi.org/10.4314/br.v2i1.28540
Naqvi SB, Shaikh D, Usmanghani K, Shameel M, Shaikh R. 1992. Screening of marine algae of Karachi for haemagglutinin activity. Pakistan Journal of Pharmaceutical Sciences 5(2), 129-138.
Sumner J. 2000.The Natural History of Medicinal Plants. Timber Press. 16 P.
Sarker SD, Nahar L. 2007. Chemistry for Pharmacy Students General, Organic and Natural Product Chemistry. England: John Wiley and Sons. 283-359 P.
Sasidharan S, Chen Y, Saravanan D,Sundram KM , Yoga Latha L. 2011. Extraction, Isolation and Characterization of Bioactive Compounds from Plants’ Extracts. African Journal of Traditional, Complementary and Alternative Medicines 8(1), 1-10.
Arshad Farid, Bashir Ahmad, Muhammad Yasin, Fazal Haq, Muhammad Bilal Khan, Shafiullah Khan, 2017. Haemagglutination and Antibacterial activities of Strobilanthes urticifolia Wall. ex Kuntze. Int. J. Biosci., 11(4), 35-40.
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