home icon user icon
Welcome to International Network for Natural Sciences | INNS Pub.
Home My Account
Submit Manuscript
double_slash
breadcumb_bg

HBV prevalence in the volunteer blood donors in Peshawar, Khyber Pakhtunkhwa Pakistan

Paper Details

Research Paper 01/11/2018
Views (257) Download (13)
current_issue_feature_image
publication_file

HBV prevalence in the volunteer blood donors in Peshawar, Khyber Pakhtunkhwa Pakistan

Ihtesham ul Haq, Mehran Khan, Zahid Rehman, Faheem Anwar, Habib Ullah, Noor Ullah
Int. J. Biosci.13( 5), 50-54, November 2018.
Certificate: IJB 2018 [Generate Certificate]
Key: ELISAHBVKTHWHO

Abstract

Hepatitis B is a fatal liver disease caused by the hepatitis B virus. In Pakistan, there are estimated 7-9 million carriers of hepatitis B virus (HBV) with a carrier rate of 3-5%. An estimated two billion people have been infected with hepatitis B virus (HBV) which is the 10th leading cause of death in the world. The World Health Organization (WHO) estimates that there are 350 million people with chronic HBV infection. This study was designed to determine anti-HBV prevalence based on ELISA (Enzyme Linked Immune Sorbent Assay), among blood donors in Khyber Teaching Hospital (KTH), a tertiary care hospital in Peshawar Khyber-Pakhtunkhwa province of Pakistan. A total of 8634 blood samples were collected during June 2017 to November 2017 in the blood bank of KTH, Peshawar. All samples were tested for anti-HBV antibodies using ELISA Technique. Analysis of all 8634 blood donors indicated that 127 individuals (1.47%) had anti-HBV antibodies in their sera. According to our study the prevalence of HBV infection is even lower (1.47%) than the common HBV prevalence recorded in the case of all previous studies in our subject areas. The decreasing movement of HBV infection indicates the development in health care facilities and awareness among the common population over the past few years.

VIEWS 7
Cover PDF

Alter MJ. 2003. Epidemiology and prevention of hepatitis B. Seminars in Liver Disease 23(1), 39–46.

Basit A, Rahim K, Ahmad I, Shafiqe M, Mushtaq S, Khan I, Shaheen H. 2014. Prevalence of hepatitis B and C infection in Pakistan. J. Inf. Mol. Biology 2(3), 35-38.

Biswas A, Panigrahi R, Pal M, Chakraborty S, Bhattacharya P, Chakrabarti S, Chakravarty R. 2013. Shift in the hepatitis B virus genotype distribution in the last decade among the HBV carriers from eastern India: possible effects on the disease status and HBV epidemiology. J Med Virol.  85, 1340–1347.

Chaudhary IA, Samiullah, Khan SS, Masood A, Faqeer F. 2004. Seroprevalence of hepatitis R, Sardar MA, Mallhi AA. Seroprevalence of B, C and HIV in healthy blood donors in Hepatitis B and C among the healthy blood Northwest of Pakistan. Pakistan J Pathol donors at Fauji Foundation Hospital 15, 1 1-6.

Franco E, Bagnato B, Marino MG. 2012. Hepatitis B: epidemiology and prevention in developing countries. World J Hepatol 4, 74–80.

Javed Iqbal Farooqi, Rukhsana Javed Farooqi, Nowshad Khan. 2006. Mussarat Department of Medicine and Department of Pulmonology Government Lady Reading Hospital, Peshawar and Khyber Teaching Hospital, Peshawar, Pakistan

Jawad ahmad, Abid suhailtaj, abdurrahim, Afzal shah, Muhammad Rehman. 2003. Department of pathology Rehman medical institute Peshawar Pakistan.

Kao JH. 2007. Role of viral factors in the natural course and therapy of chronic hepatitis B. Hepatol Int.  1, 415–430.

Khokhar N, Gill ML, Malik GJ. 2000. General Prevalence of hepatitis B carrier and HIV in seroprevalence of hepatitis C and hepatitis B healthy blood donors at Ayub Teaching in population. J Coll Physicians Surg Pak. Hospital. Pakistan J Med Research 39, 91-2.

Lee WM. Hepatitis Virus Infection B, Eng1 N, Med J. 1997. 337, 1733–45.

Lin CL, Kao JH, Hepatitis B. 2015. virus genotypes and variants. Cold Spring Harb Perspect Med.  5, a021436.

Mahmood MA, Khawar S, Anjum AH, Ahmed SM, Rafiq S, Nazir I. 2004. Prevalence of Hepatitis B, C and HIV infection in blood donor donors of Multan region. Ann KE Med Coll 10, 459-61.

Mason WS, Seeger C. 1991. Hepadenavirus-molecular biology and pathogenesis. Curr. Top. Microbiol. Immunol. 168(1).

Muhammad Ali, Muhammad Idrees, Liaqat Ali, Abrar Hussain, Irshad Ur Rehman, Sana Salem, Samia Afzal, Sadia Butt Ali. 2011. Virology Journal 8, 102.

Najib Ullah Khan1, Lubna Siddique1, Ijaz Ali1, Aqib Iqbal1, Iqbal Munir1, Farzana Rashid2, Sajid Ali3, Fazal Raziq, Zahoor Ahmad Swati1. 2010. African Journal of Biotechnology 9(37), 6162-6166, Available online at ISSN 1684–5315 ©2010 Academic Journals. http://www.academicjournals.org/AJB

Noor ali S, Hakim ST, Mclean D, Kazmi SU. Bagasra O. 2008. J. Infect. Develop. Count 2, 373-3786.

Deleted. Previsani N, Lavanchy D. 2002. WHO/CDS/CSR/LYO/Hepatitis 2.

Geneva: World Health Organization. 2002. Hepatitis B.

Roman S, Panduro A. 2013.  HBV. Endemicity in Mexico is associated with HBV genotypes H and G. World J Gastroenterology 19, 5446–5453.

Siddique KM, Sohag AA. 2010. Hepatitis B and C; Share of young rural populace of Sindh. Med. Chan., 16, 215-218.

Butt T. 2008. Amin 2 Eastern Mediterranean Health Journal 14(4),

World Health Organization. 2000. Hepatitis B fact sheet. (Online) Available from: http://www.who.int/mediacentre/factsheets/fs204/en/.

Yosaf M, Hasan SMA, Kazmi SH. 1998. Prevalence of HBsAg among volunteer blood donors in Bahawalpur division. The Professional Medical Journal 5, 167-71.

Submit Manuscript