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Histological evaluation of the thymocyte composition in the thymus gland of mice by using soft laser

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Research Paper 01/07/2018
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Histological evaluation of the thymocyte composition in the thymus gland of mice by using soft laser

Ahmed Anwar Albir
Int. J. Biosci.13( 1), 65-71, July 2018.
Certificate: IJB 2018 [Generate Certificate]
Key: Histological alterationsMedical LaserMiceThymocytes of the thymus gland

Abstract

Background: Thymus is composed of two lobes and it is located in the mediastinum, each one is split up into many lobules and each of them is separated from another by trabeculae that consist of connective tissue. The author used thymus gland as a target for soft laser in order to achieve better results due to hypothetical effects on its composition mainly thymocytes.The presented research was aimed to find the possible effect of soft laser on the cellular composition of the normal thymus gland of mice. Thirty three of normal male from Swiss albino mice at 9 weeks of age and body weight 41-49 gm were the targets for this experimental study. These mice were separated into three groups (11mice/group). The first group was kept as a control and was not subjected to radiation of the laser, while the rest of the groups were exposed to laser irradiation. The outcomes of this study show how laser caused marked alterations in the cellular contents of the thymus glands of the second group of mice mainly the thymocytes which included increased size of the thymocytes and multiplication of the cellular nuclei. The mentioned alterations were more plentiful in the thymocytes composition of the thymus glands of the last set of mice irradiated with laser. Soft laser proved the hypothesis and caused noticeable atterations in the thymocytes structure and that in turn could support the immune system as well.

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