Honey as a topical antibacterial agent for treatment of superficial infected wounds

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Research Paper 01/07/2019
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Honey as a topical antibacterial agent for treatment of superficial infected wounds

Muhammad Owais Ahmed Khan, Khan Usmanghani, Abdul Hannan, Noor-Us-Sabah, Ejaz Mohiuddin, Syed Zahoor-Ul- Hassan Zaidi
Int. J. Biosci.15( 1), 564-571, July 2019.
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The excessive use of antibiotics has led to the ever increasing emergence of resistant strains. Honey as a natural source possessing antibacterial activity could be a good alternative to antibiotics. It is a cost effective natural remedy, easily available and has longer shelf life. It is a single product having antibacterial, anti-inflammatory, antiseptic and analgesic properties, all in one. This study aims to find an efficacious alternative to antibiotics used for the treatment of infected wounds which would be much cost effective and do not result in development of resistant organisms. A randomized controlled trial for healing of infected acute partial thickness skin wounds was conducted on 196 subjects treated with Honey in the test group and Triple Antibiotic Ointment with Pain Reliever in the control group. The difference between the baseline parameters among the two groups was statistically insignificant. Bates-Jensen Wound Assessment Tool was used for the assessment of wound healing. The level of the significance (α) was set to be 0.05. Results with p-value less than 0.05 were considered statistically significant. Rapid healing time was noted for honey as compared to the Triple Antibiotic Ointment with Pain Reliever. The mean healing time was 14.06 days for honey while 15.65 days for Triple Antibiotic Ointment. There was an appreciable difference in the reduction of size among the test group at day 5 (p-value of 0.028) and at day 10 (p-value of 0.007). This research demonstrates that honey could be an effective alternative for the treatment of infected skin wounds.


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