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Remdesivir-A Possible Therapeutic Measure to Stem the Pandemic Wave

By: Umer Farooq, Aroosh Shabbir, Arsalan Fazal, Maryam Khan, Saba Shamim

Key Words: Coronaviruses, COVID-19, Remdesivir, MERS-CoV, SARS-CoV-2, FDA.

Int. J. Biosci. 18(3), 59-73, March 2021.

DOI: http://dx.doi.org/10.12692/ijb/18.3.59-73

Certification: ijb 2021 0177 [Generate Certificate]

Abstract

The year 2020 will always be recalled in human history as the year of the COVID-19 pandemic. Its crisis at the global level has united scientists all over the world for the development of potential therapeutic drugs for its treatment. Remdesivir remains in limelight owing to its efficacy. The initial clinical trials showed a better benefit-ratio profile ratio. However, its safety is not established yet. The drug is under investigation. The ongoing clinical trials have proposed a better benefit-risk profile of remdesivir as compared to the placebo. Both in vitro and in vivo, remdesivir is one of the potential drugs which has demonstrated its efficacy against the Coronaviruses. It has also shown its promising support as a compassionate use drug for the clinical improvement of patients in the COVID-19 challenge. It is expected from the clinical trials progress that remdesivir will show the outstanding breakthroughs for the global COVID-19 challenge. Moreover, FDA approval has created a hope that the use of remdesivir may be helpful in the mitigation of morbidity, mortality, and the burden on the health care systems due to COVID-19 in the future.

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Remdesivir-A Possible Therapeutic Measure to Stem the Pandemic Wave

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Umer Farooq, Aroosh Shabbir, Arsalan Fazal, Maryam Khan, Saba Shamim.
Remdesivir-A Possible Therapeutic Measure to Stem the Pandemic Wave.
Int. J. Biosci. 18(3), 59-73, March 2021.
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