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Impact of chronic exercise training on pro-inflammatory cytokine interleukine-6 in adult men with asthma

Research Paper | February 1, 2014

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Ali Jalalvand, Masoud Moeini, Javad Almasi, Naser Farokhroo

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J. Bio. Env. Sci.4( 2), 358-363, February 2014


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Evidence supports an important contribution of low-grade systemic inflammation in asthma or chronic obstructive pulmonary disease. The objective of present study was to determine whether aerobic training program affect serum IL-6 in males with asthma. For this purpose, fasting blood samples were collected before and at the end of aerobic training (3 months/3 days weekly) in order to measuring serum interleukin-6 in twenty two adult men with chronic asthma that randomly divided into exercise or control groups. Anthropometrical markers were also measured before and after exercise program in two groups. Independent student T test was used for between group’s comparison at baseline and paired T test used for determine significant changes in variables by exercise intervention. Exercise program decreases body weight, body mass index and body fat percentage compared to baseline. There were no significant differences for serum IL-6 [pre, 5.33(3.6); post, 5.65(2.71) pg/ml (p = 0.76)]. These data suggest that long term aerobic training is not associated with an anti-inflammatory property in asthma patients. Further studies are necessary to elucidate the significance of this exercise program on other inflammatory cytokines.


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Impact of chronic exercise training on pro-inflammatory cytokine interleukine-6 in adult men with asthma

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