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In vitro antibacterial activity of Cannabis sativa leaf extracts to some selective pathogenicbacterial strains

Muhammad Naveed, Tahir Ali Khan, Izhar Ali, Adil Hassan, Hamid Ali, Zaheer Ud Din, Zohaib Hassan, Shumaila Tabassum, Saqib, Abdul Majid, Mujaddad Ur Rehmanndiram Dhumal, Gorakh Pondhe

DOI: https://dx.doi.org/10.12692/ijb/4.4.65-70

Int. J. Biosci. 4(4), 65-70. February, 2014. (PDF)

Abstract:

Plant materials are important for animal and human health care and also important for microbial controlling program. This present stud  has been attempt to determine the antibacterial activit  of Cannabis sativa leaf extract to some selective pathogenic  bacterial strains such as Staph lococcus aureus,  Escherichia coli, Pseudomunas aeruginosa, Enterococcus faecalis, Salmonella t phi and Klebsiella b using leaf ethanol extract and Hot water extract. Antibacterial activit  of Cannabis  sativa was evaluated b well diffusion methods. The highest zone of inhibition produced b   ethanol extract. The leaf of Cannabis Sativa exerted pronounced antibacterial activit  (24.1mm) against  Staph lococcus aureus, (10.3mm) against Pseudomonas aeruginosa, (22.2mm) against Escherichia coli, (18.1mm) against Enterococcus faecalis respectivel  and inactive against the two strains, Salmonella t phi and Klebsiella. The minimum inhibitor effect of C. sativa leaf extract is due to certain compounds present in the C. Sativa. Further research should be done to identif  the compounds responsible for its activit  which can be used as medicines to control a wide range of disease in the world.