In vitro antifungal activity of Embelia schimperi (Vatke) and Conyza floribunda

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Research Paper 01/09/2018
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In vitro antifungal activity of Embelia schimperi (Vatke) and Conyza floribunda

Elibariki Eliangilisa Kowero, Cecilia Leweri, Musa Chacha
Int. J. Biosci.13( 3), 45-50, September 2018.
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The study aimed to investigate antifungal activity of 2 medicinal plants namely Embelia schimperi and Conyza floribunda used in Tanzania to treat infectious diseases. Micro-dilution method was used to evaluate antifungal activity of plant extracts against Cryptococcus neuformans and Candida albicans. The study revealed that tested extracts have different levels of antifungal activity with minimum inhibition concentration (MIC) range of 0.78 mg/mL to >25 mg/mL. The Conyza floribunda root chloroform extract (CFRC) inhibited both C. albicans and C. neoformans at MIC value of 0.78 mg/mL. Conyza floribunda leaf ethyl acetate (CFLE) and Embelia schimperi stem methanolic extract (ESSM) exhibited antifungal activity at MIC value of 0.78 mg/mL against C. neoformans. The results obtained suggest that CFRC, CFLE and ESSM is a potential source of antifungal secondary metabolites.


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