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In vitro antimalarial activity of essential oils of Deverra scoparia Coss. & Dur

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Research Paper 01/01/2018
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In vitro antimalarial activity of essential oils of Deverra scoparia Coss. & Dur

Roukia Hammoudi, Soulaymene Sanon, Mahfoud Hadj Mahammed
J. Bio. Env. Sci.12( 1), 1-4, January 2018.
Certificate: JBES 2018 [Generate Certificate]
Key: ActivityAntimalarialApiaceaeDeverra scopariaEssential oil

Abstract

The essential oils of the plant Deverra scoparia Coss. & Dur. (Apiaceae) used in traditional medicine in Algeria were subjected to testing the antimalarial activity. Their potential ability to inhibit the in vitro proliferation was evaluated in two strains of Plasmodium falciparum; chloroquine-resistant (K1), and chloroquine-sensitive (3d7) strains. The essential oils displayed good antimalarial activity with IC50 values 1.51 ± 0.71 μg/mL and 0.93 ± 0.89 μg/mL against the 3d7 chloroquine-sensitive and the K1 chloroquine-resistantstrains respectively. So, Deverra scoparia presented a potential source of antimalarial molecules.

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