Influence of L-carnitine on blood values of broiler chickens exposed to 16l:8d and 8l:16d photoperiod regimes

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Research Paper 01/12/2017
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Influence of L-carnitine on blood values of broiler chickens exposed to 16l:8d and 8l:16d photoperiod regimes

Jay P. Picardal
Int. J. Biosci.11( 6), 255-268, December 2017.
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Abstract

Different photoperiod regimes demonstrate promising potential in improving carcass weight and reduction of body fat. However, attaining normal blood values in the presence of feed supplements under a certain photoperiod regime has not been explored yet in broilers. The study investigated the effects of 200 ppm L-carnitine and photoperiod on hematological values of broilers (12-day old, n=60). A 2×2 factorial design in RCBD was carried out to produce four treatment groups (15 replicates/ group); T1 = 16 hours light:8 hours dark without L-carnitine, T2 = 16L:8D with L-carnitine, T3 = 8L:16D with L-carnitine and T4 = 8L:16D without L-carnitine. At 42 days, interaction effects of photoperiod and L-carnitine were significant for RBC count, hemoglobin and packed cell volume (p<0.05). Abdominal fat was lower by 1.66% and 1.51% in L-carnitine-supplemented chickens exposed to 16L:8D and 8L:16D compared to unsupplemented treatment groups (T1 and  T4 ), respectively. Results also show that in all blood parameters studied, RBC (1.57-2.24×106/µL) was found below the reference range (2.5-3.5×106/µL) while lymphocyte differential count was higher (68.5-81.2%) than the reference range (45-70%). Eosinophil and monocyte were also found to be lower than the reference values, while hemoglobin, PCV, MCV, MCH, MCHC, heterophil, basophil, clotting time and bleeding time were within the normal range for chickens. The study concluded that supplementation of L-carnitine improved production performance as evidenced by lower % abdominal fat than an unsupplemented group. L-carnitine works better at a photoperiod of 16L:8D by improving RBC count, hemoglobin and packed cell volume (PCV).

VIEWS 10

Abbas AO, El-Dein AA, Desoky AA, Galal MA. 2008. The effects of photoperiod programs on broiler chicken performance and immune response. International Journal of Poultry Science 7(7), 665-671.

Albarece SC Jr. 1963. Observations on the erythrocytes and leucocyte counts and Packed Cell Volume of the Japanese Quails. Undergraduate Thesis. College of Veterinary Medicine, University of the Philippines, Diliman, Quezon City.

Altan Ö, Settar P, Ünver Y, Çabuk M. 2005. Heritabilities of tonic immobility and leucocytic response in sire and dam layer lines. Turkish Journal of Veterinary and Animal Sciences 29(1), 3-8.

Apeldoorn EJ, Schrama JW, Mashaly MM, Parmentier HK. 1999. Effect of melatonin and lighting schedule on energy metabolism in broiler chickens. Poultry Science 78(2), 223-229. https://doi.org/10.1093/ps/78.2.223

Bieber LL. 1988. Carnitine. Annual Review of Biochemistry 57(1), 261-283. https://doi.org/10.1146/annurev.bi.57.070188.001401

Bremer J. 1983. Carnitine metabolism and functions. Physiology Review 63, 1420-1480. https://doi.org/10.1152/physrev.1983.63.4.1420

del Pilar Lanzarot M, Montesinos A, San Andrés MI, Rodríguez C, Barahona MV. 2001. Hematological, protein electrophoresis and cholinesterase values of free-living nestling peregrine falcons in Spain Journal of Wildlife Diseases 37(1), 172-178. https://doi.org/10.7589/0090-3558-37.1.172

Campbell N. 1996. Biology. 4th Ed. Benjamin-Cummings Publishing Company Inc. CA, USA.1206.

Campbell TW, Coles EH. 1986. Avian Clinical Pathology. In Coles, EH (Ed.), Veterinary Clinical Pathology. 4th Ed. Saunders CO., Philadelphia USA. 279-300.

Campoto E. 2005. Immuno-competence of native chicken (Gallus gallus domesticus) given Virgin Coconut Oil. Proceedings of the 2nd In-house Review for Research, Extension and Production Projects. College of Agriculture and Natural Sciences, Eastern Samar State University, Borongan City, Eastern Samar, Philippines, p 1-10.

Classen HL. 2004. Day length affects performance, health and condemnations in broiler chickens. Proceedings of the Australian Poultry Science Society, University of Sydney, Sydney, NSW.

Classen HL, Riddell C. 1989. Photoperiodic effects on performance and leg abnormalities in broiler chickens. Poultry Science 68(7), 873-879. https://doi.org/10.3382/ps.0680873

Classen HL, Riddell C, Robinson FE. 1991. Effects of increasing photoperiod length on performance and health of broiler chickens. British Poultry Science 32(1), 21-29. https://doi.org/10.1080/00071669108417324

Coles EH. 1974. Veterinary Clinical Pathology. WB Saunders Company.

Coles EH. 1986. Veterinary Clinical Pathology. WB Saunders Company. 4th Ed. Philadelphia, p 486.

Fairchild B. 2003. Fundamentals of light management in broiler production. The Poultry Informed Professional, Issue No. 72. Department of Avian Medicine, Univ. of Georgia, USA.

Feller AG, Rudman D. 1988. Role of carnitine in human nutrition. The Journal of Nutrition 118, 541-547.

Genazzani AR, De Ramundo BM, Criscuolo M, De Gaetani C, Ficarra G, Genazzani AD, Petraglia F, Trentini GP. 1990. Acetyl-l-carnitine restores the daily pattern of hypothalamic β-endorphin in rats exposed to continuous light. European Journal of Pharmacology 186(2-3), 177-180. https://doi.org/10.1016/0014-2999(90)90431-5

Gillespie JR. 1995. Modern Livestock and Poultry Production.5th Ed. International Thomson Publishing Company.

Graczyk S, Pliszczak-Król A, Kotonski B, Wilczek J, Chmielak Z. 2003. Examination of hematological and metabolic changes mechanisms of acute stress in turkeys. Electronic Journal of Polish Agricultural University Veterinary Medicine 6(5), 1-10.

Gross WB. 1989. Factors affecting chicken thrombocyte morphology and the relationship with heterophil: lymphocyte ratios. British Poultry Science 30(4), 919-925. https://doi.org/10.1080/00071668908417218

Gross WB, Siegel SH. 1983. Evaluation of the heterophil / lymphocyte ratio as a measure of stress in chickens. Avian Diseases 27(4), 972-979. https://doi.org/10.2307/1590198

Gross WB, Siegel PB. 1986. Effects of initial and second periods of fasting on heterophil / lymphocyte ratios and body weight. Avian Diseases. 30(2), 345-346. https://doi.org/10.2307/1590539

Guyton AC 1992. Medical Physiology, 7th Ed. Saunders Company, Philadelphia USA., p 900.

Harrison GL, Lightfoot TL. 2006. Clinical Avian Medicine. Spix Publishing, Inc. Palm Beach, Fl., USA., p 1008.

Jain NC. 1993. Essential of Veterinary Hematology, Lea and Febiger, Philadelphia.

Khan AT, Zafar F. 2005. Haematological  study  in  response  of  varying  doses  of  estrogen  in  broiler chicken. International Journal of Poultry Science 4(10), 748-751.

Maala CP, Landicho EF, Solis CD, Borja LF. 2002.  Blood Values, Bleeding Time and Coagulation Time of Blood in Locally Raised Fighting Cocks. Philippine Journal of Veterinary and Animal Sciences 28(2), 68-76.

Mader S. 2004. Human Biology. 8th Ed. McGrawHill, NY USA., p 541.

Maxwell MH, Hocking PM, Robertson GW. 1992. Differential leucocyte responses to various degrees of food restriction in broilers, turkeys and ducks. British Poultry Science 33(1), 177-187. https://doi.org/10.1080/00071669208417455

Merck’s Veterinary Manual. 1986. Editor: Fraser, 6th Edition. Merck and Company, Rahway, NJ, USA.

Neuman SL, Lin TL, Heste PY. 2002.  The effect of dietary carnitine on semen traits of White Leghorn roosters. Poultry Science (4), 495-503. https://doi.org/10.1093/ps/81.4.495

Petek M, Sönmez G, Yildiz HÜ, Baspinar H. 2005. Effects of different management factors on broiler performance and incidence of tibial dyschondroplasia. British Poultry Science 46(1), 16-21. https://doi.org/10.1080/00071660400023821

Phillips KM. 1999. Psittacine blood collection and hematology: Basics for the Veterinary Practitioners. Department of medical microbiology, College of veterinary medicine, University of Georgia, Athens, GA 30602 USA.

Rabie MH, Szilagyi M, Gippert T. 1997a. Effects of dietary L-carnitine supplementation and protein level on performance and degree of meatness and fatness of broilers. Acta Biologica Hungarica 48(2), 221-239. https://doi.org/10.1007/BF03543192

Rabie MH, Szilagyi M, Gippert T, Votisky E, Gerendai D. 1997b. Influence of dietary L-carnitine on performance and carcass quality of broiler chickens. Acta Biologica Hungarica 48(2), 241-252. https://doi.org/10.1007/BF03543193

Rebouche CJ. 1991. Ascorbic acid and carnitine biosynthesis. The American Journal of Clinical Nutrition 54(6), 1147S-52S.

Rebouche CJ, Paulson DJ. 1986. Carnitine metabolism and function in humans. Annual Review of Nutrition 6(1), 41-66. https://doi.org/10.1146/annurev.nu.06.070186.000353

Renden JA, Bilgili SF, Lien RJ, Kincaid SA. 1991. Live performance and yields of broilers provided various lighting schedules. Poultry Science 70(10), 2055-2062. https://doi.org/10.3382/ps.0702055

Ritchie BW, Harrison JG, Harrison RL. 1994. Avian Medicine. Winger’s Publishing, Inc. Florida USA.

Rosskopf W, Woerpel R. 1996. Diseases of cage and aviary birds, 3rd Ed. Williams and Wilkins, Baltimore USA.

Samour J. 2006. Diagnostic value of hematology. In Harrison GL, Lightfoot TL. 2006. Clinical Avian Medicine. Spix Publishing, Inc. Palm Beach, Fl., USA., p 1008.

Sarica S, Corduk M, Kilinc K. 2005. The effect of dietary L-carnitine supplementation on growth performance, carcass traits, and composition of edible meat in Japanese quail (Coturnix coturnix japonica). Journal of Applied Poultry Research 14(4), 709-715. https://doi.org/10.1093/japr/14.4.709

Schneider SH. 1989. Poultry Science and Technology Guide. Extension Poultry Science, North Carolina State University, Raleigh NC, USA.

Shini S. 2003. Physiological responses of laying hens to the alternative housing systems. International Journal of Poultry Science 2(5), 357-360.

Siegel HS. 1995. Stress, Strains and Resistance. British Poultry Science 36, 3-22. https://doi.org/10.1080/00071669508417748

Simaraks S, Chinrasri O, Aengwanich W. 2004. Hematological, electrolyte and serum biochemical values of the Thai indigenous chickens (Gallus domesticus) in northeastern, Thailand. Songklanakarin Journal of Science and Technology 26(3), 425-430.

Sturkie PD. 1965. Avian Physiology 2nd ed. London, Bailliére, Tindall and Cassell.

Svenson JE. 1977. Biology of a Norwegian pheasant population. Meddr. Norsk Viltforsk 3(5), 1-24.

Vleck CM, Vertalino N, Vleck D, Bucher TL. 2000. Stress, corticosterone, and heterophil to lymphocyte ratios in free-living Adélie penguins. The Condor 102(2), 392-400. https://doi.org/10.1093/condor/102.2.392

Yeste M, Sancho S, Briz M, Pinart E, Bussalleu E, Bonet S. 2010. A diet supplemented with L-carnitine improves the sperm quality of Pietrain but not of Duroc and Large White boars when photoperiod and temperature increase. Theriogenology 73(5), 577-586. https://doi.org/10.1016/j.theriogenology.2009.10.013

Zulkifli I, Rasedee A, Syaadoh O, Norma MT. 1998. Daylength effects on stress and fear responses in broiler chickens. Asian-Australasian Journal of Animal Sciences 11(6), 751-754. https://doi.org/10.5713/ajas.1998.751