Is antibacterial PNA the answer for combating multidrug resistant bacterial infections?
Paper Details
Is antibacterial PNA the answer for combating multidrug resistant bacterial infections?
Abstract
The emergence of multidrug resistant bacterial infections is a serious problem. Treatment options are limited to patients those are infected with multidrug resistant bacteria. We are in a desperate need of new antibiotics. Antisense oligomers of PNA (Peptide Nucleic Acid) were introduced in late 90’s as antibacterial agents in an intention to create a new class of bacterial specific antibiotic. Followed by several studies have demonstrated that antibacterial PNA oligomers are effective in a verity of pathogenic bacterial strains. Development of PNA-based drugs (PNA antibiotics) will help us to combat infections of drug resistant bacterial strains.
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Anubrata Ghosal, 2017. Is antibacterial PNA the answer for combating multidrug resistant bacterial infections?. Int. J. Biosci., 10(1), 408-410.
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