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Is antibacterial PNA the answer for combating multidrug resistant bacterial infections?

Anubrata Ghosal

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Int. J. Biosci.10(1), 408-410, January 2017

DOI: http://dx.doi.org/10.12692/ijb/10.1.408-410


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The emergence of multidrug resistant bacterial infections is a serious problem. Treatment options are limited to patients those are infected with multidrug resistant bacteria. We are in a desperate need of new antibiotics. Antisense oligomers of PNA (Peptide Nucleic Acid) were introduced in late 90’s as antibacterial agents in an intention to create a new class of bacterial specific antibiotic. Followed by several studies have demonstrated that antibacterial PNA oligomers are effective in a verity of pathogenic bacterial strains. Development of PNA-based drugs (PNA antibiotics) will help us to combat infections of drug resistant bacterial strains.


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Is antibacterial PNA the answer for combating multidrug resistant bacterial infections?

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