Lipid profile and systemic inflammation, their responses to acute cycling in obese men

Paper Details

Research Paper 01/06/2012
Views (376) Download (12)
current_issue_feature_image
publication_file

Lipid profile and systemic inflammation, their responses to acute cycling in obese men

Ahmadi Pezhman, Torabi Mohsen, Aran Ardabili Akbar, Aghazadeh Javad
J. Bio. Env. Sci.2( 6), 67-72, June 2012.
Certificate: JBES 2012 [Generate Certificate]

Abstract

Obesity is known to be associated with low-grade inflammation and insulin resistance. To evaluate of C-reactive protein fat profile markers in response to acute exercise test, these variables were measured before and after a short-time cycling test in nineteen sedentarily obese male subjects aged 35-44 years that participated by accidentally in study. Student’s paired ‘t’ test was applied to compare the pre and post training values. Serum CRP, triglyceride, total cholesterol and low density lipoprotein showed no significant changes by cycling exercise in studied subjects (P≥0.05). A significant increase were observed in high density lipoprotein in response to cycling test (p=0.021). Although cycling exercise for short time is associated with improved high density lipoprotein, but this exercise test can not improve lipid profile parameters and systemic inflammation immediately after test in obese men.

VIEWS 14

Albert CM, Ma J, Rifai N, Stampfer MJ, Ridker PM. 2002. Prospective study of C-reactive protein, homocysteine, and plasma lipid levels as predictors of sudden cardiac death. Circulation 105(22), 2595-9.

Bruun JM, Lihn AS, Verdich C, Pedersen SB, Toubro S, Astrup A, Richelsen B. 2003. Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans. Am J Physiol Endocrinol Metab 285, 527– 33.

Church TS, Barlow CE, Earnest CP. 2002. Associations between cardiorespiratory fitness and C-reactive protein in men. Arterioscler Thromb Vasc Biol 22, 1869- 76.

De Ferranti S, Rifai N. 2002. C-reactive protein and cardiovascular disease: a review of risk prediction and interventions. Clin Chim Acta 317, 1– 15.

Gielen S, Adams V, Mobius-Winkler S, Linke A, Erbs S, Yu J, Kempf W, Schubert A, Schuler G, Hambrecht R. 2003. Anti-inflammatory effects of exercise training in the skeletal muscle of patients with chronic heart failure. J Am Coll Cardiol 42, 861–868.

Grunfeld C, Feingold KR. 1996. Regulation of lipid metabolism by cytokines during host defense, Nutrition 12, 24–26.

Hutchinson WL, Koenig W, Fröhlich M, Sund M, Lowe GD, Pepys MB. 2000. Immunioradiometric assay of ciurculating C-reactive protein: age related values in the adult general population. Clinical Chemistry 46, 934-8.

Ishii T, Yamakita T, Sato T, Tanaka S, Fujii S. 1998. Resistance training improves insulin sensitivity in NIDDM Subjects without altering maximal oxygen uptake. Diabetes Care 21(8), 1353-5.

Khera A, McGuire DK, Murphy SA, Stanek HG, Das SR, Vongpatanasin W. 2005. Race and gender differences in C-reactive protein levels. J Am Coll Cardiol 46, 464-9.

LaMonte MJ, Durstine JL, Yanowitz FG. 2002. Cardiorespiratory fitness and C-reactive protein among a tri-ethnic sample of women. Circulation 106, 403 – 6.

Le Maitre JP, Harris S, Fox KA, Denvir M. 2004. Change in circulating cytokines after 2 forms of exercise training in chronic stable heart failure. Am Heart J 147, 100–105.

Li YP, Chen Y, John J, Moylan J, Jin B, Mann DL, Reid MB. 2005. TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle. FASEB J 19, 362–370.

Marcell TJ, McAuley KA, Traustadóttir T, Reaven PD. 2005. Exercise training is not associated with improved levels of C-reactive protein or adiponectin. Metabolism 54(4), 533-41.

Moldoveanu AI, Shephard RJ, Shek PN. 2000. Exercise elevates plasma levels but not gene expression of IL-1beta, IL-6, and TNF-alpha in blood mononuclear cells. J Appl Physiol. 89(4), 1499-504.

Mullis R, Campbell IT, Wearden AJ, Morriss RK, Pearson DJ. 1999. Prediction of peak oxygen uptake in chronic fatigue syndrome. British Journal of Sports Medicine 33(5), 352-6.

Nicklas BJ, Ambrosius W, Messier SP, Miller GD, Penninx BW, Loeser RF, Palla S, Bleecker E, Pahor M. 2004. Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial. Am J Clin Nutr 79, 544–551.

Nicklas BJ, You T, Pahor M. 2005. Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training. CMAJ 172, 1199–209.

Pfützner A, Schöndorf T, Hanefeld M, Forst T. 2010. High-Sensitivity C-Reactive Protein Predicts Cardiovascular Risk in Diabetic and Nondiabetic Patients: Effects of Insulin-Sensitizing Treatment with Pioglitazone. J Diabetes Sci Technol 4(3), 706-16.

Reamer RR,  Chu H,  Castracane DV.  2000. Leptin and exercise. Exp Biol Med 227, 701–708.

Ridker  PM.  2003.  Clinical  application  of  C- reactive protein for cardio-vascular disease detection and prevention. Circulation 107(3), 363-9.

Schultz DR, Arnold PI. 1990. Properties of four acute  phase  proteins:  C-reactive  protein,  serum amyloid   A   protein,   a1-acid   glycoprotein   and fibrinogen. Semin Arthritis Rheum 20, 129–47.

White  LJ,  Castellano  V,  McCoy  SC.  2006. Cytokine responses to resistance training in people with multiple sclerosis. J Sports Sci 24, 911–914.