Maximal oxygen consumption in response to aerobic exercise program and its relation to insulin action in diabetic patients

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Research Paper 01/01/2013
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Maximal oxygen consumption in response to aerobic exercise program and its relation to insulin action in diabetic patients

Eizadi M, Dooaly H, Kiani F, Khorshidi F
J. Bio. Env. Sci.3( 1), 110-115, January 2013.
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Obesity is related to chronic diseases such as syndrome metabolic and type II diabetic. The aims of present study were 1) to evaluate effect long term aerobic exercise on physical fitness and some marker indicator of type II diabetic in healthy obese men, 2) to determine relation between the change pattern of aerobic capacity and the other mentioned variables in response to this aerobic exercise program. For this purpose, a total thirty adult obese males participated in this study and were randomly divided into experimental or control groups. The experimental group subjects were participated in an aerobic exercise program (3 months / 3 times weekly) and control group did not participate in any exercise session. Aerobic capacity, fasting insulin and glucose were measured in two separate occasions in each 2 groups (before and after aerobic program). Insulin resistance was calculated with fasting glucose and insulin. Statistical analysis was performed using an independent paired t-test. Pearson correlation was used to establish the relationship between the changes pattern between variables in response to exercise program. Aerobic training program resulted in significant increase in aerobic capacity (VO2max) and significant decrease in insulin resistance and fasting glucose in experimental group. The change in VO2max was inversely associated with the change in fasting glucose and directly associated with the change in beta cell function. These data highlight that cardiovascular or physical fitness response to aerobic exercise training is independent of glucose homeostasis and insulin action in obese subjects. Further studies are needed to clarify possible mechanisms between these variables in response to exercise training.


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