Metabolic effect of thyroxine on collagen characteristics in skin tissue of common Indian toad
Paper Details
Metabolic effect of thyroxine on collagen characteristics in skin tissue of common Indian toad
Abstract
The effect of thyroxine on alterations of biochemical parameters like collagen characteristics in both dorsal and ventral skin were investigated in our present study. Thyroxine (T4) treatment decreased the collagen synthesis in dorsal skin at a negligible amount whereas it decreased in ventral skin significantly. Thyroxine induced the crosslinking of collagen fibres by aldimine bonds in both dorsal & ventral skin as compared to the control values. The insoluble collagen decreased in both dorsal & ventral skin preventing intra & intermolecular crosslinking. On administration of thyroxine, there was a decrease in total collagen content in both dorsal & ventral skin as compared to control values.
Antonini D, Sibilio A, Dentice M, Missero C. 2014. An intimate relationship between thyroid hormone and skin: regulation of gene expression. Frontiers in Endocrinology 4, 01-09.
Bauer EA, Uitto J. 1979. Collagen in cutaneous diseases. International Journal of Dermatology 18, 251-270.
Berardi AC, Oliva F, Berardocco M, Rovere ML, Accorsi P, Maffulli N. 2014. Thyroid hormones increase collagen I and cartilage oligomeric matrix protein (COMP) expression in vitro human tenocytes. Muscles, Ligaments and Tendons Journal 4, 285-291.
Bhargava M, Lei J, Ingbar DH. 2009. Nongenomic actions of L‐thyroxine and 3,5,3’‐triiodo‐Lthyronine. Focus on ‘L‐Thyroxine vs. 3,5,3’‐triiodo‐L‐thyronine and cell proliferation: activation of mitogen‐activated protein kinase and phosphatidylinositol 3‐kinase’. American Journal of Physiology Cell Physiology 296, C977-C980.
Brahma KC, Patnaik BK. 1982. Changes in the characteristics of collagen of young male garden lizards following centrophenoxine and lysine treatment. Experimental Gerontology 17, 399-405.
Davison PF, Cannon DJ, Anderson LP. 1972. The effect of acetic acid on collagen cross-links. Connective Tissue Research 1, 205-216.
Dezonne RS, Stipursky J, Araujo AP. 2013. Thyroid hormone treated astrocytes induce maturation of cerebral cortical neurons through modulation of proteoglycan levels. Frontiers in Cellular Neuroscience 7, 1-12.
Diez JJ, Hernanz A, Medina S, Bayon C, Iglesias P. 2002. Serum concentrations of tumour necrosis factor-alpha (TNF-alpha) and soluble TNF-alpha receptor p55 in patients with hypothyroidism and hyperthyroidism before and after normalization of thyroid function. Clinical Endocrinology (Oxford) 57, 515-521.
Drobnik J, Ciosek J, Slotwinska D, Stempniak B, Zukowska D, Marczynski A, Tosik D, Bartel H, Dabrowski R, Szczepanowska A. 2009. Experimental hypothyroidism increases content of collagen and glycosaminoglycans in the heart. Journal of Physiology and Pharmacology 60, 57-62.
Fink CW, Ferguson JL, Smiley JD. 1967. Effect of hyperthyroidism and hypothyroidism on collagen metabolism. The Journal of Laboratory and Clinical Medicine 69, 950-959.
Furlow JD, Neff ES. 2006. A developmental switch induced by thyroid hormone: Xenopus laevis metamorphosis. Trends in Endocrinology and Metabolism 17, 40–47. DOI: 10.1016/j.tem.2006. 01. 007.
Garrity JA, Bahn RS. 2006. Pathogenesis of graves ophthalmopathy: Implications for prediction, prevention, and treatment. American Journal of Ophthalmology 142, 147-153.
Hnilo A. 2017. The thyroid – skin connection: how your thyroid affects skin health. https://alituranaturals.com/the-thyroid-skin-connection-how-your-thyroid-effects-skin-health/
Kivirikko KI, Koivusalo M, Laitinen G, Liesmaa M. 1963. Effect of thyroxine on the hydroxyproline in rat urine and skin. Acta Physiologica 57, 462-467.
Kivirikko KI, Laitinen O, Aer J, Halme J. 1967. Metabolism of collagen in experimental hyperthyroidism and hypothyroidism in the rat. Endocrinology 80, 1051-1061.
Leach AA. 1960. Notes on a Modification of the Neuman & Logan Method for the Determination of the Hydroxyproline. Biochemical Journal 74, 70-71.
Lee JK, Gegg CA, Hu JC, Reddi AH, Athanasiou KA. 2015. Thyroid hormones enhance the biomechanical functionality of scaffold‐free neocartilage. Arthritis Research & Therapy 17, 1-11.
Lima FR, Trentin AG, Rosenthal D, Chagas C, Moura NV. 1997. Thyroid hormone induces protein secretion and morphological changes in astroglial cells with an increase in expression of glial fibrillary acidic protein. Journal of Endocrinology 154, 167-175.
Magnan B, Bondi M, Pierantoni S, Samaila E. 2014. The pathogenesis of Achilles tendinopathy: a systemic review. Foot and Ankle Surgery 20, 154-159.
Mays PK, McAnulty RJ, Campa JS, Laurent GJ. 1991. Age-related changes in collagen synthesis and degradation in rat tissues. Importance of degradation of newly synthesized collagen in regulating collagen production. Biochemical Journal 276, 307-313.
Mendes-de-Aguiar CB, Costa-Silva B, Alvarez-Silva M, Tasca CI, Trentin AG. 2008 Thyroid hormone mediates syndecan expression in rat neonatal cerebellum. Cellular and Molecular Neurobiology 28, 795-801.
Mishra G, Panda B, Pattnaik S, Maharana P. 2018. Impact of thyroid hormone in liver collagen of Duttaphrynus Melanostictus. Indian Journal of Biology 5, 37-43. DOI: http://dx.doi.org/10.21088/ijb.2394.1391.5118.6
Muller PK, Kirsch E, Gauss-Miiller V, Krieg T. 1981. Some aspects of the modulation and regulation of collagen synthesis in vitro. Molecular and Cellular Biochemistry 34, 73-85.
Neuman RE, Logan MK. 1950. The Determination of Hydroxyproline. The Journal of Biological Chemistry 184, 299-306.
Rycker C de, Vandalem JL, Hennen G. 1984. Effects of 3,5,3’-triiodothyronine on collagen cultured human skin fibroblasts. FEBS Letters 174, 34-37.
Singh S, Mishra G. Dixit PK. 2016. Ascorbic acid (vit-c) induced biochemical alternation of collagen characteristics in heart tissues of swiss mice. International Journal of Current Research 8, 37575-37579.
Trentin AG, Gomes FC, Lima FR, Neto VM. 1998. Thyroid hormone acting on astrocytes in culture. In Vitro Cellular & Developmental Biology. Animal 34, 280-282.
Trentin AG. 2006. Thyroid hormone and astrocyte morphogenesis. Journal of Endocrinology 189, 189-197.
Whitney GA, Kean TJ, Fernandes RJ, Waldman S, Tse MY, Pang SC, Mansour JM, Dennis JE. 2017. Thyroxine increases collagen type ii expression and accumulation in scaffold-free tissue-engineered articular cartilage. Tissue Engineering Part A. 24, 369-381. DOI: 10.1089/ten.TEA.2016. 0533.s
Subhasmita Pattnaik, Gitanjali Mishra, 2018. Metabolic effect of thyroxine on collagen characteristics in skin tissue of common Indian toad. Int. J. Biosci., 13(4), 450-456.
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