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Mollugo oppositifolia leaf tea formulation and its effect against alloxan-induced hyperglycemic male sprague dawley rats

Vian Jethro T. Bariuan, Chasey T. Mabborang, Sheila Mae G. Macanas, Kenneth Christian O. Santiago, Jayvee B. Salomon, Jinky Marie T. Chua, Ramelo B. Ramirez Jr

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Int. J. Biosci.16(4), 71-78, April 2020

DOI: http://dx.doi.org/10.12692/ijb/16.4.71-78


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Hyperglycemia is one of the most prevalent health concerns worldwide which is rapidly increasing in middle and low–income families. Though Mollugo oppositifolia Linn. Is found throughout the Philippines, its blood glucose-lowering activity in its tea form has not been studied. The study was conducted to determine the hypoglycemic effects in tea – bag and spray – dried form on Sprague Dawley rats injected with 150 mg of alloxan prepared in 0.9 sodium chloride. It is noted that both tea forms have no significant difference as the commercial drug (Glibenclamide) in lowering the blood glucose concentration. This study also evaluated the formulated leaves based on its moisture content, ash content, and microbial determination, which are all within the acceptable range. Sensory evaluation was also done, and it was found that the taste, color, and aroma show characteristics expected of a green tea. It is recommended that a histopathological test should be conducted on the liver. Furthermore, that the bitter after-taste be masked.


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Mollugo oppositifolia leaf tea formulation and its effect against alloxan-induced hyperglycemic male sprague dawley rats

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