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Mycochemicals and bioactivities of Aspergillus niger and Rhizomucor pusillus associated with vermicast

Research Paper | September 1, 2018

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Jamile B. Sabado, Eden S. David, Mary Jhane G. Valentino

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Int. J. Biosci.13( 3), 306-313, September 2018

DOI: http://dx.doi.org/10.12692/ijb/13.3.306-313


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This study aimed to determine the mycochemical constituents and biological activities of fungi associated with vermicast namely: Aspergillus niger, Rhizomucor pusillus. Mycochemical screening of A. niger and R. pusillus ethanolic extract and fungal spent revealed the presence of flavonoids and terpenoids. Other bioactive compounds like tannins and alkaloids were only detected in A. niger and R. pusillus ethanolic extracts, respectively. For the antibacterial activity as protectant, at 12 hours and 24 hours of incubation, the least zone of colonization of Staphylococcys aureus and Escherichia coli were recorded in plates treated with A. niger ethanolic extract and R. pusillus ethanolic extracts. Whereas, zone of inhibition at 12 and 24 hours of incubation against the bacterial pathogens were recorded in ethanolic extract of A. niger and R. pusillus. For the DPPH radical scavenging activity, among the four extracts, A. niger ethanolic extract recorded the highest ability to scavenge free radicals. Thus, the aforementioned fungal organisms possess antimicrobial and anti-oxidant properties which can be attributed to their mycochemical components.


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Mycochemicals and bioactivities of Aspergillus niger and Rhizomucor pusillus associated with vermicast

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