Nutritional and lifestyle modifications of polycystic ovary syndrome (pcos) in obesity

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Research Paper 01/12/2019
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Nutritional and lifestyle modifications of polycystic ovary syndrome (pcos) in obesity

Momina Shahid, Maryam Naveed, Sidra Khalid, Muhammad Atif, Tabussam Tufail, Muhammad Zia Shahid, Habibur Rehman, Aimen Wahid, Muhammad Imran, Muzzamal Hussain
Int. J. Biosci.15( 6), 259-272, December 2019.
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Abstract

Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder characterized by polycystic ovaries, chronic anovulation and hyper-androgenism leading to signs of menstrual irregularity, infertility and hirsutism. Insulin resistance, obesity and high levels androgens are linked with PCOS. The contributory factors include lazystandards of living, dietary dissimilarities, lack of exercise and anxiety etc.There appears to be an epidemic of both obesity and polycystic ovary syndrome (PCOS) in the world today. Obesity is not a cause of PCOS, as the high prevalence of PCOS among relatively thin populations demonstrate. However, obesity does worsen many aspects of the phenotype, especially cardiovascular risk factors such as glucose intolerance and dyslipidemia. It is also associated with a poor response to infertility treatment and likely an increased risk for pregnancy complications in those women who do conceive. Although most treatments of obesity, with the exception of bariatric surgery, achieve modest reductions in weight and improvements in the PCOS phenotype, encouraging weight loss in the obese patient remains one of the front-line therapies plus life style modification is also very encouraging. However, new studies are required to identify the best interventions, and the role of lifestyle therapies in women of normal weight with PCOS is uncertain.

VIEWS 28

Ahn J, Choi W, Kim S, Ha T. 2011. Anti-diabetic effect of watermelon (Citrullus vulgaris Schrad) on Streptozotocin-induced diabetic mice. Food science and biotechnology 20, 251-254.

AOAC. 2006. Official methods of analysis of AOAC international, 18th Ed. J. Association of Official Analytical Chemists. USA.

Aqil F, Gupta A, Munagala R, Jeyabalan J, Kausar H, Sharma R, Singh IP, Gupta RC. 2012. Antioxidant and antiproliferative activities of anthocyanin/ ellagitannin-enriched extracts from Syzygiumcumini L. (‘jamun’, the Indian Blackberry). Nutr. Cancer 64, 428-438.

Arun R, Prakash MVD, Abraham SK, Premkumar K. 2011. Role of Syzygiumcumini seed extract in the chemoprevention of in vivo genomic damage and oxidative stress. Journal of ethnopharmacology 134, 329-333.

Baliga MS, Fernandes S, Thilakchand KR, D’souza P, Rao S. 2013. Scientific validation of the antidiabetic effects of Syzygiumjambolanum DC (black plum), a traditional medicinal plant of India. The Journal of Alternative and Complementary Medicine 19, 191-197.

Benherlal PS, Arumughan C. 2007. Chemical composition and in vitro antioxidant studies on Syzygiumcumini fruit. Journal of the Science of Food and Agriculture 87, 2560-2569.

Bhowmik D, Gopinath H, Kumar BP, Kumar K. 2013. Traditional and medicinal uses of Indian black berry. Journal of Pharmacognosy and Phytochemistry 1.

Choudhary RK, Swarnkar PL. 2011. Antioxidant activity of phenolic and flavonoid compounds in some medicinal plants of India. Natural product research 25, 1101-1109.

Coelho EM, De Azevedo LC, Corrêa LC, BordignonLuiz MT, Lima MDS. 2016. Phenolic Profile, Organic Acids and Antioxidant Activity of Frozen Pulp and Juice of the Jambolan (S yzygiumCumini). Journal of Food Biochemistry 40, 211-219.

Dias CN, Rodrigues KA, Carvalho FA. Carneiro SM, Maia JG, Andrade EH, Moraes DF. 2013. Molluscicidal and leishmanicidal activity of the leaf essential oil of Syzygiumcumini (L.) SKEELS from Brazil. Chemistry & biodiversity 10, 1133-1141.

Dias CN, Rodrigues KAF, Carvalho FAA, Carneiro SMP, Andrade EHA, Moraes DFC. 2013. Molluscicidal and leishmanicidal activity of the leaf essential oil of Syzygiumcumini (L.) Skeels from Brazil. Chem. Biodivers 10, 1133-1141.

Grover JK, Vats V, Rathi SS. 2000. Anti-hyperglycemic effect of Eugenia jambolana and Tinosporacordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. Journal of Ethnopharmacology73, 461-470.

Grover JK, Vats V, Rathi SS. 2000. Anti-hyperglycemic effect of Eugenia jambolana and Tinosporacordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. Journal of Ethnopharmacology 73, 461-470.

Jadhav VM, Kamble SS, Kadam VJ. 2009. Herbal medicine: Syzygiumcumini: A review. Journal of Pharmacy Research 2, 1212-1219.

Jagetia GC, Baliga MS. 2002. Syzygiumcumini (Jamun) reduces the radiation-induced DNA damage in the cultured human peripheral blood lymphocytes: a preliminary study. Toxicology letters 132, 19-25.

Koley TK, Barman K, Asrey R. 2011. Nutraceutical properties of jamun (Syzygiumcumini L.) and its processed products. Indian Food Industry 30, 34-37.

Mitra SK, Gopumadhavan S, Muralidhar TS. Anturlikar SD, Sujatha MB. 1995. Effect of D-400, a herbomineral preparation on lipid profile, glycated haemoglobin and glucose tolerance in streptozotocin induced diabetes in rats. Indian J ExpBiol 33, 798-800.

Modak M, Dixit P, Londhe J, Ghaskadbi S, Devasagayam TPA. 2007. Recent advances in Indian herbal drug research guest editor: Thomas Paul AsirDevasagayam Indian herbs and herbal drugs used for the treatment of diabetes. Journal of clinical biochemistry and nutrition 40, 163-173.

Pari L, Saravanan G. 2002. Antidiabetic effect of cogent db, a herbal drug in alloxan-induced diabetes mellitus. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 13, 19-25.

Pepato MT, Folgado VBB, Kettelhut IC.  Brunetti IL. 2001. Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes. Brazilian Journal of Medical and Biological Research 34, 389-395.

Ravi K, Ramachandran B, Subramanian S. 2004. Effect of Eugenia jambolana seed kernel on antioxidant defense system in streptozotocin-induced diabetes in rats. Life sciences 75, 2717-2731.

Raza A. 2015. Antihypercholesterolmic role of ethanolic extract of jamun (syzygiumcumini) fruit and seed in hypercholesterolmic Rats. American-eurasian Journal of Agriculture and Environmental Sciences 15.

Raza ASU, Malook MU, Ali MN, Akram I, Wazir M, Sharif N. 2015. Antihypercholesterolemic role of ethanolic extract of jamun (Syzygiumcumini) fruit and seed in hypyercholesterolemic rats. American-Eurasian Journal of Agricultural & Environmental Sciences 15, 1012-1018.

Rizvi SI, Mishra N. 2013. Traditional Indian medicines used for the management of diabetes mellitus. Journal of diabetes research.

Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. 1999. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free radical biology and medicine 26, 1231-1237.

Shahnawaz M, Nizamani SM, Bhanger MI, Afridi I, Ahmed E. 2012. A study on the determination of mineral elements in jamun fruit (Eugenia jambolana) products. Pakistan Journal of Nutrition 11, 181-186.

Sharma SB, Tanwar RS, Nasir A, Prabhu KM. 2011. Antihyperlipidemic effect of active principle isolated from seed of Eugenia jambolana on alloxan- induced diabetic rabbits. Journal of Medicinal Food 14, 353-359.

Srivastava S. Chandra D. 2013. Pharmacological potentials of Syzygiumcumini: A review. Journal of the Science of Food and Agriculture 93, 2084-93.

Steel RG, Torrie DJH, Dickey D. 1997. Principles and Procedures of Statistics: A Biometrical Approach. 3rd Ed. McGraw Hill Book Co Inc. New York.

Tupe RS, Sankhe NM, Shaikh SA, Phatak DV, Parikh JU, Khaire AA, Kemse NG. 2013. Aqueous extract of some indigenous medicinal plants inhibits glycation at multiple stages and protects erythrocytes from oxidative damages-an in vitro study. Journal of Food Science and Technology 43, 295-304.