Welcome to International Network for Natural Sciences | INNSpub

Paper Details

Research Paper | February 1, 2011

| Download

Observational study of new treatment proposal for severe intrauterine adhesion

Umme Salma, Dabao Xu, M Sayed Ali Sheikh

Key Words:

Int. J. Biosci.1(1), 43-56, February 2011


IJB 2011 [Generate Certificate]


To present the experience with intrauterine adhesiolysis under observational study of new treatment proposal for severe intrauterine adhesion to prevent the formation of adhesion and it is comparison with the review articles. Sixty patients for whom operative hysteroscopy were indicated referred to the hysteroscopic unit of University-affiliated Xiang ya 3rd hospital, Hunan, china. The adhesions were divided hysteroscopically by using scissors or electrode needle under direct vision. A second look hysteroscopy was performed after one month. Total five operative procedures were performed in 59 cases; one patient did not continue her treatment. One was mild adhesion, two were moderate adhesions and 56 were normal cavity after final treatment. The staging mean score of intrauterine adhesion was evaluated, patients showed a significant decrease in severity of adhesion at 1.69% (stage I mild adhesions), and 3.38% (stage II moderate adhesions).At one month follow-up hysteroscopic adhesiolysis significantly reduce the development of intrauterine adhesions postoperatively and its use is likely to be associated with a reduction of severe adhesions.


Copyright © 2011
By Authors and International Network for
Natural Sciences (INNSPUB)
This article is published under the terms of the Creative
Commons Attribution Liscense 4.0

Observational study of new treatment proposal for severe intrauterine adhesion

Acunzo G, Guida M, Pellicano M, Tommaselli GA, Di Spiezio Sardo A,Bifulco G. 2003. Effectiveness of auto-cross-linked hyaluronic acid gel in Bifulco G the prevention of intrauterine adhesions after, after hysteroscopic adhesiolysisl a prospective, randomized, controlled study. Hum. Repro. 18, 1918–21.

Capella-Allouc S, Morsad F, Rongieres-Bertrand C,Taylor S, Fernandez H. 1999.Hysteroscopic treatment of severe Asherman’s syndrome and subsequent fertility. Hum. Repro. 14, 1230–3.

Comninos AC, Zourlas PA. 1996. Treatment of uterine adhesions (Asherman’s syndrome). Am. J. Obstet. Gynecol. 105, 862–5.

Dan Yu, Yat-May Wong, Ying Cheong, EnlanXia, Tin-ChiuLi. 2008.Asherman syndrome—one century later a Hysteroscopic Center, Fu Xing Hospital, Capital Medical University, Beijing, People’s Republic of China; b Department of Obstetrics and Gynecology, Jessop Wing, Royal Hallamshire Hospital, Sheffield, United Kingdom; and c Private Practice, Kular Lumpar, Malaysia.

Diamond MP, Freeman ML. 2001.Clinical implications of postsurgical adhesions. Hum. Repro. Update 7, 567–76.

Diamond MP. 2000. Incidence  of  postsurgical  adhesions.  In  diZerega  G  (Ed.). Peritoneal Surgery (Sprinter-Verlag, New York) pp, 217–20.

Doyle  MB,  Lavy  G.  1991.  Intrauterine  synechiae  and  pregnancy  loss.  Infertil. Repro. Med. Clin. North. Am. 2, 91-103.

Duffy S, Reid PC, Sharp F. 1992. In-vivo studies of uterine electrosurgery. Br. J. Obstet. Gynaecol. 99, 579–82.

Farhi J, Bar-Hava I, Homburg R, Ben-Rafael Z. 1993.Induced regeneration of endometrium following curettage for abortion: a compa study. Hum. Repro. 8, 11434.

Friedler S, Margalioth EJ, Kafka I, Yaffe H. 1993. Incidence of post-abortion intra-uterine adhesions evaluated by hysteroscopy—a prospective study. Hum. Repro. 8, 442–4.

Fayez JA. 1986. Comparison between addominal and hysteroscopic metroplasty. Obstet. Gynecol. 68, 339–41.

Guida M, Acunzo G, Di Spiezio Sardo A, Bifulco G, Piccoli R, Pellicano. 2004. Effectiveness of auto-crosslinked hyaluronic acidgel in the prevention of intrauterine adhesions after hysteroscopi surgery: a prospective, randomized, controlled study. Hum. Repro. 19, 1461–4.

Jehn-Hsiahn Yang, Mei-Jou Chen, Ming-Yih Wu, Kuang-Han Chao, Hong-Nerng Ho, Yu-Shih Yang. 2008.Office hysteroscopic early lysis of intrauterine adhesion after transcervical resection of multiple apposing submucous. Department of Obstetrics and Gynecology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Jewelewicz R, Khalaf S, Neuwirth RS, VandeWiele RL. 1976. Obstetric complications after treatment of intrauterine synechiae (Asherman’s syndrome). Obstet. Gynecol. 47,701–5.

Klein SM, Garcia C-R. 1973. Asherman’s syndrome: a critique and curren view. Fertil. Steril.  24, 722.

Knopman J, Copperman AB. 2007. Value of 3D ultrasound in the management of suspected Asherman’s syndrome. J. Repro. Med. 52, 1016-1022.

Kongnyuy EJ, van den Broek N, wiysonge CS. 2008. A systemic review of randomized controlled trials to reduce hemorrhage during myomectomy for uterine fibroids. Int. J. Gynaecol. Obstet. 10, 4-9.

Louros NC, Danezis JM, Pontifix G. 1968. Use of intrauterine devices in the treatment of intra-uterine adhesions. Fertil. Steril. 19, 509–28.

Lurie S, Appelman Z, Katz Z. 1991. Curettage after midtrimester termination of pregnancy. Is it necessary? J. Repro. Med. 36, 786–788.

Massouras HG. 1973. Intrauterine adhesions: a syndrome of the past, with the use of the ‘‘Massouras’’ Duck’s Foot No. 2 IUD. Am. J. Obstet. Gyneco.116, 576.

Nappi A, Sardo DS, Greco E, Bettocch S, Bifulco G. 2007.Human Reproduction Update Advance Access published online on April 23, 2007 Human Reproduction Update, doi:10.1093/humupd/dml061 Prevention of adhesions in gynaecological endoscopy C.Department of Gynaecology and Obstetrics, and Pathophysiology of Human Reproduction, University of Naples ‘Federico II’, Via Pansini 5, Naples, Italy 3 Department of General and Specialistic Surgical Sciences, Section of Obstetrics and Gynaecology, University of Bari, Italy.

Orhue AAE, Aziken ME, Igbefoh JO. 2003. A comparison of two adjunctive treatments for intrauterine adhesions following lysis. Int. J. Gynecol. Obstet. 8, 49-56.

Pabuccu R, Atay V, Orhon E. 1997. Hysteroscopic treatment of intrauterine adhesions is safe and effective in the restoration of normal menstruation and fertility. Fertil. Steril. 68, 1141–3.

Preutthipan S, Linasmita V. 2000. Reproductive outcome following hysteroscopic lysis of intrauterine adhesions: a result of 65 cases at Ramathibodi Hospital. J. Med. Assoc. Thai. 83, 42–6.

Polishuk WZ, Anteby SO, Weinstein D. 1975. Puerperal endometritis and intrauterine adhesions. Int Surg. 60, 418-20.

Polishuk WZ, Weinstein D. 1976. The Soichet intrauterine device in the treatment of intrauterine adhesions. Acta. Eur. Fertil. 7, 215.

Romer T. 1994. Post-abortion-hysteroscopy—a method for early diagnosis of congenital and acquired intrauterine causes of abortions. Eur. J. Obstet. Gynecol. Repro. Biol. 57, 171–3.

Roge P, Cravello L, D’Ercole C, Broussse M, Broussse M, Boubli L, Blanc B. Intrauterine adhesions  and   fertility:   results   of   hysteroscopic    treatment. Gynaecol. Endosc.  6, 225–8.

Schenker JG, Margalioth EJ. 1982. Intrauterine adhesions: an updated appraisal. Fertility and Sterility 37, 593–610.

Schenker JG. 1996. Etiology of and therapeutic approach to synechia uteri. Eur. J. Obstet. Gynecol. Repro. Biol. 65, 109–13.

Siddiqui S, Zuberi NF, Zafar A, Qureshi RN. 2003. Increased risk of cervical canal infections with intracervical Foley catheter. J. Coll. Physicians Surg. Pak. 13,146–9.

Thomas JA, Leyland N, Durand N, 2002.the use of oral misoprostal as a cervical ripening agent in operative hysteroscopy: a duble-blind, placebo-controlled trial. Am. J. Obstet. Gynecol. 186, 876-879.

Valle RF, Sciarra JJ. 1988. Intrauterine adhesions: hysteroscopic diagnosis, classification, treatment, and reproductive outcome. Am. J. Obstet. Gynecol. 158,1459–70.


Style Switcher

Select Layout
Chose Color
Chose Pattren
Chose Background