Organic feed additive Alpha-Bio+ as an alternative to chemical antibiotics: Effect on zootechnical performance and coccidial burden in laying hens Lohmann Brown

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Research Paper 25/09/2025
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Organic feed additive Alpha-Bio+ as an alternative to chemical antibiotics: Effect on zootechnical performance and coccidial burden in laying hens Lohmann Brown

Coulibaly Assetou Ya, Yapi Jean Noel, Kadjo Vincent, Ouattara N’Golo , Yao Kouakou
Int. J. Biosci. 27(3), 221-228, September 2025.
Copyright Statement: Copyright 2025; The Author(s).
License: CC BY-NC 4.0

Abstract

The excessive and uncontrolled use of synthetic antibiotics in poultry farms promotes the emergence of resistant germs, leading to health problems, reduced performance and increased mortality, which results in significant economic losses. This study aims to reduce the use of these antibiotics by proposing natural therapeutic alternatives. More specifically, it aims to evaluate the effect of the organic feed additive Alpha-Bio+ as alternative to chemical antibiotics on zootechnical performance and coccidial load. The study, conducted on 600 Lohmann Brown chicks at Nangui Abrogoua University, compared a control batch (conventional veterinary prophylaxis) with an experimental batch treated with the organic feed additive Alpha-Bio+ as a substitute for antibiotics. All subjects were raised under identical conditions. The evaluated parameters included feed intake (FI), body weight, average daily gain (ADG), feed conversion ratio (FCR), mortality, and parasitic load. The results showed a slight improvement in body weight and ADG in the experimental batch. Furthermore, this batch recorded a significantly better FCR at the end of the rearing period, along with a markedly lower parasitic load, with no observed reinfection, unlike the control batch. Alpha-Bio+ thus proved to be an effective alternative to conventional veterinary treatments, improving both zootechnical performance and digestive health in pullets.

Abou-Elkhair R, Ahmed HA, Selim S. 2014. Effects of black pepper (Piper nigrum), turmeric powder (Curcuma longa) and coriander seeds (Coriandrum sativum) and their combinations as feed additives on growth performance, carcass traits, some blood parameters and humoral immune response of broiler chickens. Asian-Australasan Journal of Animal Sciences 27(6), 847-854. https://dx.doi.org/10.5713/ajas.2013.13644

Awais MM, Akhtar M, Muhammad F, Haq AU, Anwar MI. 2011. Immunotherapeutic effects of some sugar cane (Saccharum officinarum L.) extracts against coccidiosis in industrial broiler chickens. Experimental Parasitology 128(2), 104-110. https://dx.doi.org/10.1016/j.exppara.2011.02.024

Awan ZH, Shah MAA, Zafar MA, Farooq AA, Shoaib M, Kamran M, Iqbal MF, Hussain R, Khan MA, Javid MA, Mukhtar T, Murtaz-ul-Hassan, Mohyuddin SG. 2023. Prevalence and chemotherapy of coccidial infections in broilers in Muzaffarabad. Pakistan Journal of Science 75(1), 44-50.

Blake DP, Knox J, Dehaeck B, Huntington B, Rathinam T, Ravipati V, Ayoade S, Gilbert W, Adebembo AO, Jatau ID, Raman M, Parker D, Rushton J, Tomley FM. 2020. Re-calculating the cost of coccidiosis in chickens. Veterinary Research 51(1), 115. https://doi.org/10.1186/s13567-020-00837-2

Chapman HD. 1977. Biochemical, genetic and applied aspects of drug resistance in Eimeria parasites of the fowl. Avian Pathology 26(2), 221-44. PMID: 18483904.https://dx.doi.org/10.1080/03079459708419208.

Coulibaly AY, Soro OS, Ouattara NG, Nadiara D. 2024. Efficiency of the feed additive ALPHA-BIO+ as an alternative to antibiotics on the eggs production performance of the layer Lohman Brown, International Journal of Innovation and Applied Studies 43(2), 423-430.

Fatoba AJ, Adeleke MA. 2018 Diagnosis and control of chicken coccidiosis: a recent update. Journal of Parasitic Diseases 42, 483-493. https://doi.org/10.1007/s12639-018-1048-1

Giannenas I, Papadopoulos E, Tsalie E, Triantafillou E, Henikl S, Teichmann K, Tontis D. 2012. Assessment of dietary supplementation with probiotics on performance, intestinal morphology and microflora of chickens infected with Eimeria tenella. Veterinary Parasitology 188(1-2), 31-40. https://doi.org/10.1016/j.vetpar.2012.02.017.

Kabir SML. 2009. The role of probiotics in the poultry industry. International Journal of Molecular Sciences 10(8), 3531-3546. https://doi.org/10.3390/ijms10083531

Lee KW, Lillehoj HS, Jang SI, Kim DK, Ionescu C, Bravo D. 2007. Effects of Pediococcus- and Saccharomyces-based probiotic (MitoMax) on coccidiosis in broiler chickens. Comparative Immunology Microbiology and Infectious Diseases 30(4), 261-268. https://doi.org/10.1016/j.cimid.2007.02.002.

Mesa-Pineda C, Navarro L, Lopez SC, Gutiérrez J, Gomez-Osorio LM. 2021. Chicken Coccidiosis: From the Parasite Lifecycle to Control of the Disease. Frontiers in Veterinary Science 8, 787653. https://doi.org/10.3389/fvets.2021.787653.

Mohsin M, Zhang Z, Yin G. 2022. Effect of Probiotics on the Performance and Intestinal Health of Broiler Chickens Infected with Eimeria tenella. Vaccines 10(1), 97. https://doi.org/10.3390/vaccines10010097.

Mountzouris KC, Tsitrsikos P, Palamidi I, Arvaniti A, Mohnl M, Schatzmayr G, Fegeros K. 2010. Effects of probiotic inclusion levels in broiler nutrition on growth performance, nutrient digestibility, plasma immunoglobulins, and cecal microflora composition. Poultry Science 89(1), 58-67. https://doi.org/10.3382/ps.2009-0030.

Patterson JA, Burkholder KM. 2003. Application of prebiotics and probiotics in poultry production. Poultry Science 82(4), 627-631. https://doi.org/10.1093/ps/82.4.627.

Peek HW, Landman WJ. 2011. Coccidiosis in poultry: anticoccidial products, vaccines and other prevention strategies. Veterinary Quarterly 31(3), 143-61. https://doi.org/10.1080/01652176.2011.605247.

Shirley MW, Smith AL, Tomley FM. 2005. The biology of avian Eimeria with an emphasis on their control by vaccination. Advances in Parasitology 60, 285-330. https://doi.org/10.1016/S0065-308X(05)60005-X.

Silué FE, Ouattara H, Méité A, N’Goran KDV, Véronique C, Kati-Coulibay S. 2020. Performances Zootechniques, Économiques et Qualité Physique des Œufs Des Poules Soumises À des Régimes Alimentaires Apportant Différentes Concentrations De Tourteau D’amandes de Noix de Cajou (Côte d’Ivoire). European Scientific Journal 16(3), 472-488. https://doi.org/10.19044/esj.2020.v16n3p472.

Tossou ML., Houndonougbo PV, Akouedegni CG, Houndonougbo MF, Abiola FA, Chrysostome CAAM. 2019. Effet de la souche sur les performances zootechniques et économiques de poulettes élevées au Sud Bénin. Revue Marocaine des Sciences Agronomiques et Vétérinaires 7(4), 544-549.

Yadav S, Jha R. 2019. Stratégies to modulate the intestinal microbiota and their effects on nutrient utilization, performance, and health of poultry. Journal of Animal Science Biotechnology 10, 2. https://doi.org/10.1186/s40104-018-0310-9

Zhang G, Wang H, Zhang J, Tang X, Raheem A, Wang M, Lin W, Liang L, Qi Y, Zhu Y, Jia Y, Shangjin C, Qin T. 2021. Modulatory Effects of Bacillus subtilis on the Performance, Morphology, Cecal Microbiota and Gut Barrier Function of Laying Hens. Animals 11, 1523.https://doi.org/10.3390/ani11061523.

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