Paper Details

Phylogenetic study of disease-resistant genes in silico

Mahsa Mohammad Jani Asrami, Hamid Najafi Zarrini

DOI: https://dx.doi.org/10.12692/ijb/6.2.237-241

Int. J. Biosci. 6(2), 237-241. January, 2015. (PDF)

Abstract:

Despite singnificant advances in plant disease control strategies, but also a large number of pathogens and pests are bringing a lot of damage. By comparing the amino acid sequences of proteins encoded by the resistance genes in plants with different evolutionary origin has been shown that resistance genes based on structural similarity to the protein products of the NBS-LRR (Nucleotide binding Site-Leucine Rich Repeats), LRR extracellular, LRR-kinase receptors are classified. This study investigate the relationship between protein sequences of gene in various plants, their intraction was determined Bioinformatics software. The protein sequence cluster analysis identified which these genes are located in three groups. Arabidopsis thaliana plant containing the resistance gene RLM1 located in a seprate group . Evolutionary distance matrix results showed that most distance (0.99) between the plant Populus trichocarpa and Solanum lypersicum and the minimum distance (0.287) between Solanum lypersicum and Vitis vinifera. The results of the simulated rank protein that resistance genes are far apart and have not a similar origin. Functional results Rlm1 gene in Arabidopsis thaliana revealed that this gene is located on chromosome 1 and united with intercellular or extracellular signals in transmission of signals from a membrane to the other works.