Phytochemical property and oral toxicity safety of Chrysophyllum caimito and Psidium guajava extracts

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Research Paper 11/02/2023
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Phytochemical property and oral toxicity safety of Chrysophyllum caimito and Psidium guajava extracts

Roel T. Calagui
J. Bio. Env. Sci.22( 2), 18-25, February 2023.
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The century-old practice of herbal medication in animals still persists in local communities despite the contemporary advances in veterinary health care today. The numerous benefits including convenience of use, accessibility, inexpensiveness and insignificant side effects when compared to synthetic veterinary medicines in which drug resistance and residuals are linked. This research work aimed to elucidate the presence of bioactive components and determine the margin of safety of Chrysophyllum cainito (Caimito) and Psidium guajava (Guava) ethanolic bark extracts which are among the selection of documented herbals reliably utilized for gastro-intestinal sicknesses in farm animals. Qualitative phytochemical screening exemplified the presence of tannins, saponins, terpenoids, xanthoproteins, steroids and coumarin. Avian acute oral toxicity testing denoted that 2000mg/kg dosage was adequate and safe to use in Sasso chickens as substantiated by insignificant effect to body weight, SGOT and uric acid values and the non-appearance of toxicity symptoms including death. The secondary metabolites demonstrated in these plants explicate the pharmacological activities which can be utilized as potential alternatives to current medication strategies in animals.


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